Publications by authors named "Jiaying Zong"
High-mobility group box 1 protein is involved in the protective effect of Saquinavir on ventilation-induced lung injury in mice.
Acta Biochim Biophys Sin (Shanghai)
October 2017
Article Synopsis
- * A study with C57BL/6 mice examined the effects of SQV on lung injury caused by high tidal volume ventilation (HTV), revealing that HTV led to significant lung damage and activation of inflammatory markers like TNF-α and IL-6.
- * SQV pretreatment was found to reduce lung inflammation and damage, suggesting its protective effect is linked to the inhibition of harmful inflammatory pathways such as NF-κB activation and HMGB1 expression.
Background: The increasing use of the transversus abdominis plane (TAP) block, as a form of pain relief after laparoscopic surgery, warrants evaluation of its effectiveness, when compared with other analgesic techniques.
Methods: We searched online databases of MEDLINE, EMBASE, Google scholar and The Cochrane Database of Systematic Review. Mean differences (MD) were formulated for continuous data; odds ratios (OR) were calculated for dichotomous data.
Background: Ketamine is traditionally avoided in sedation management of patients with risk of intracranial hypertension. However, results from many clinical trials contradict this concern. We critically analyzed the published data of the effects of ketamine on intracranial pressure (ICP) and other cerebral hemodynamics to determine whether ketamine was safe for patients with hemodynamic instability and brain injuries.
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