Unveiling the Origin of Oxygen Framework Stability in Ultra-High Nickel Layered Oxide Cathodes.

Ultra-high nickel layered oxides are recognized as promising cathode candidates for high-energy-density lithium-ion batteries due to their enhanced overall capacity and elevated operating voltage. However, the interlayer sliding of transition metal-oxygen octahedra (TMO6) and the instability of lattice oxygen at high voltages for ultra-high nickel oxide cathodes pose significant challenges to their development. Herein, the origin of oxygen framework stability is investigated by incorporating high-covalent element Mo in both bulk and surface using a one-step integrated method for ultra-high nickel cathode material LiNiCoO.

A nomogram to predict sarcopenia in middle-aged and older women: a nationally representative survey in China.

Background: Sarcopenia is a disease characterized by losing muscle mass, strength, and function with age. Studies have shown that sarcopenia is generally higher in women than in men. Therefore, this study used the 2015 China Health and Retirement Longitudinal Study (CHARLS) data to explore further the risk factors associated with sarcopenia in middle-aged and older Chinese women.

Small-Angle Neutron Scattering for Lithium-Based Battery Research: Progress and Perspective.

Lithium-based batteries have become the mainstream energy storage system due to their high energy density and long cycle life, driving rapid advancements in smart electronics and electric vehicles. However, the development of lithium-based batteries has encountered several difficult technical challenges, including safety issues and capacity degradation, which result from uncontrollable dendrite growth, complex interface reactions, and volume expansion. There is an urgent need to develop in situ characterization techniques to elucidate the complex evolution processes during battery operation.

Primary duodenal T/histiocyte-rich large B-cell lymphoma complicated with obstructive jaundice: A case report and review of literature.

Background: T/histiocyte-rich large B-cell lymphoma (T/HRBCL) is a highly aggressive subtype of diffuse large B-cell lymphoma characterized histologically by the presence of a few neoplastic large B cells amidst an abundant background of reactive T lymphocytes and/or histiocytes. T/HRBCL commonly affects the lymph nodes, followed by extranodal sites, such as the spleen, liver, and bone marrow, with rare occurrences in the gastrointestinal tract. Primary gastrointestinal T/HRBCL lacks specific clinical and endoscopic manifestations, and it is difficult to differentiate from inflammatory diseases, nodular lymphocyte predominant Hodgkin lymphoma, and other diseases on a histological basis, thereby hindering early diagnosis.

ApWD40a, a Member of the WD40-Repeat Protein Family, Is Crucial for Fungal Development, Toxin Synthesis, and Pathogenicity in the Ginseng Alternaria Leaf Blight Fungus .

, the primary pathogen that causes ginseng Alternaria leaf blight disease, can lead to a 20-30% reduction in ginseng yield. WD40 repeat-containing proteins are evolutionarily conserved proteins with diverse functions between different organisms. In this study, we characterized the roles of a WD40 repeat-containing protein in .

Anti-inflammatory and antioxidant properties of oleuropein in human keratinocytes characterized by bottom-up proteomics.

Oleuropein is a phenolic compound commonly found in cosmetic ingredients including olive leaves and jasmine flowers with various skin-beneficial effects. Here, we evaluated oleuropein's anti-inflammatory and antioxidant activities in human skin cells. In a cell-based inflammasome model with human monocytes (THP-1 cells), oleuropein (12-200 µM) reduced proinflammatory cytokine interleukin (IL)-6 by 38.

Cellular Senescence Contributes to Colonic Barrier Integrity Impairment Induced by Toxoplasma gondii Infection.

Toxoplasma gondii (T. gondii) induces gut barrier integrity impairment, which is crucial to the establishment of long-term infection in hosts. Cellular senescence is an imperative event that drives disease progression.

Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential.

The fungal Bromodomain and Extra-Terminal (BET) protein Bdf1 is a potential antifungal target against invasive fungal infections. However, the need to selectively inhibit both Bdf1 bromodomains (BDs) over human orthologs and the lack of molecular tools to assess on-target antifungal efficacy hamper efforts to develop Bdf1 BD inhibitors as antifungal therapeutics. This study reports a phenyltriazine compound that inhibits both Bdf1 BDs from the human fungal pathogen Candida glabrata with selectivity over the orthologous BDs from the human BET protein Brd4.

Improvement in Compatibility and Drug Release Performance of Hot-Melt Pressure-Sensitive Adhesives by Physical Blending Technique.

Background: Hot-melt Pressure-sensitive Adhesives (HMPSA) are eco-friendly pressuresensitive adhesives, with the potential of being used as substrates for transdermal patches. However, due to the low hydrophilicity of HMPSA, the application is limited in the field of Traditional Chinese Medicine (TCM) plasters.

Methods: Three modified HMPSA were prepared with acrylic resin EPO, acrylic resin RL100, and Polyvinylpyrrolidone (PVP) as the modifying materials.

Complete genome sequence of strain SOCE 003, a marine bacterium isolated from the surface seawater of Dapeng Bay.

is a heterotrophic bacterium commonly found in diverse marine environments. Here, we report the complete genome sequence of strain SOCE 003, which is 5,154,101 bp long, encoding 5,524 annotated protein-coding genes, 39 tRNAs, and 8 rRNAs. This genome information will help us understand the ecology of .

Liquid Metal Elastomer-Based U-Shaped Electrode Flexible Strain Sensors with Enhanced Stability and Sensitivity.

Soft and stretchable strain sensors are crucial for applications in human-machine interfaces, flexible robotics, and electronic skin. Among these, capacitive strain sensors are widely used and studied; however, they face challenges due to material and structural constraints, such as low baseline capacitance and susceptibility to external interference, which result in low signal-to-noise ratios and poor stability. To address these issues, we propose a U-shaped electrode flexible strain sensor based on liquid metal elastomer (LME).

Photovoltaic Array Fault Diagnosis and Localization Method Based on Modulated Photocurrent and Machine Learning.

Photovoltaic arrays are exposed to outdoor conditions year-round, leading to degradation, cracks, open circuits, and other faults. Hence, the establishment of an effective fault diagnosis system for photovoltaic arrays is of paramount importance. However, existing fault diagnosis methods often trade off between high accuracy and localization.

HandFI: Multilevel Interacting Hand Reconstruction Based on Multilevel Feature Fusion in RGB Images.

Interacting hand reconstruction presents significant opportunities in various applications. However, it currently faces challenges such as the difficulty in distinguishing the features of both hands, misalignment of hand meshes with input images, and modeling the complex spatial relationships between interacting hands. In this paper, we propose a multilevel feature fusion interactive network for hand reconstruction (HandFI).

Dual-Anion-Rich Polymer Electrolytes for High-Voltage Solid-State Lithium Metal Batteries.

Solid polymer electrolytes (SPEs) are promising candidates for lithium metal batteries (LMBs) owing to their safety features and compatibility with lithium metal anodes. However, the inferior ionic conductivity and electrochemical stability of SPEs hinder their application in high-voltage solid-state LMBs (HVSSLMBs). Here, a strategy is proposed to develop a dual-anion-rich solvation structure by implementing ferroelectric barium titanate (BTO) nanoparticles (NPs) and dual lithium salts into poly(vinylidene fluoride) (PVDF)-based SPEs for HVSSLMBs.

Development of multiple genome-wide proteome microarrays comprised wafer substrate-based chip and its scanner: An advanced high-throughput and sensitivity for molecular interactions studies.

Proteome microarray technology enables high-throughput analysis of protein interactions with all kinds of molecules. Wafer (6-inch) substrates offer a promising alternative to conventional glass (2.6 × 7.

Dissolving microneedle synergistic rocaglamide-loaded liposome to regulate abnormal neutrophils for anti-psoriasis.

Psoriasis seriously affects the physical and mental health of patients. Rocaglamide (RocA), derived from Aglaia odorata, exhibits potent pharmacological activities. Although its efficacy in psoriasis is unclear, RocA could be a promising therapeutic drug.

Glutamatergic neurons of basolateral amygdala mediate increased exploratory behaviors produced by mildly chronic restraint stress in adolescent mice.

In response to stressors, individuals manifest varied behavioral responses directed toward satisfying physiological survival needs. Although the enduring effects of adolescent stress on both humans and animals are well-documented, the underlying mechanisms remain insufficiently elucidated. Utilizing immunofluorescence, viral injections, and brain slice electrophysiological recordings, we have delineated that heightened excitability among glutamatergic neurons in the basolateral amygdala (BLA) is responsible for inducing heightened exploratory behaviors in adolescent mice subjected to mild, chronic restraint stress.

Rational design and characterization of enhanced alcohol-inducible synthetic promoters in .

The C1 and C2 alcohols hold great promise as substrates for biomanufacturing due to their low cost and rich resources. is considered a preferred host for methanol and ethanol bioconversion due to its natural utilization of methanol and ethanol. However, the scarcity of strong and tightly regulated alcohol-inducible promoters limits its extended use.

Greater neural pattern similarity to the native language is associated with better novel word learning.

Introduction: Previous neuroimaging studies on bilingualism revealed that individuals tend to apply their native-language (L1) neural strategies to second language (L2) learning and processing. Nevertheless, it is still unclear how the utilization of the L1 neural strategies affects visual word learning in a new language.

Methods: To address this question, the present study scanned native Chinese speakers while performing implicit reading tasks before 9-day form-meaning learning in Experiment 1 and before 12-day comprehensive word learning in Experiment 2.

Development of RT-dPCR method and reference material for rotavirus G3P8 and G9P8.

The rotavirus (RV) is the predominant causative pathogen associated with acute gastroenteritis in children aged below 5 years, leading to an annual mortality rate of 200,000 infants globally. Despite the development of a vaccine, it exacerbates the medical burden around the world. Here, we have developed reverse transcription digital PCR (RT-dPCR) methods for precise and absolute quantification of nucleic acid in rotavirus G3P8 and G9P8.

Identifying subgroups benefiting from intensive glycaemic treatment to improve renal outcomes in type 2 diabetes: Insights from the ACCORD trial.

Aims: The ACCORD trial showed that intensive glucose-lowering therapy has a limited impact on renal function decline. We aimed to identify subgroups in the ACCORD population that might derive renal benefits from intensive glucose-lowering therapy.

Materials And Methods: The primary renal outcome included a ≥50% decline in baseline estimated glomerular filtration rate or end-stage renal disease (ESRD).

CeO as Electron Donor in CoCeO Solid Solution Boosts Alkaline Water Splitting.

Optimizing the electronic structure with increasing intrinsic stability is a usual method to enhance the catalysts' performance. Herein, a series of cerium dioxide (CeO) based solid solution materials is synthesized via substituting Ce atoms with transition metal (Co, Cu, Ni, etc.), in which CoCeO shows optimized band structure because of electron transition in the reaction, namely Co (3d4s) + Ce (4f5d 6s) → Co (3d4s) + Ce (4f5d6s), with more stable electronic configuration.

YAP1 preserves tubular mitochondrial quality control to mitigate diabetic kidney disease.

Renal tubule cells act as a primary site of injury in diabetic kidney disease (DKD), with dysfunctional mitochondrial quality control (MQC) closely associated with progressive kidney dysfunction in this context. Our investigation delves into the observed inactivation of yes-associated protein 1 (YAP1) and consequential dysregulation of MQC within renal tubule cells among DKD subjects through bioinformatic analysis of transcriptomics data from the Gene Expression Omnibus (GEO) dataset. Receiver operating characteristic curve analysis unequivocally underscores the robust diagnostic accuracy of YAP1 and MQC-related genes for DKD.

Manufacturing enterprises move towards sustainable development: ESG performance, market-based environmental regulation, and green technological innovation.

The traditional extensive development of the manufacturing industry has caused significant environmental damage. Consequently, the manufacturing sector urgently needs a green transformation to achieve sustainable development. The primary goal of current research is to examine the extent to which green technological innovation (GTI) impacts enterprises' environmental, social, and governance (ESG) performance.