Background: A reduction in biodiversity and alterations in the microbiota composition are relevant to allergic diseases. However, combined analyses of the skin, nasal and gut microbiotas are lacking in the literature. In addition, in previous studies, microbiota were detected mainly by V3-V4 sequencing, but other sequences might be missed with this technique.
View Article and Find Full Text PDFBackground: This study aimed to develop a clinical-radiomics model using hyperattenuated imaging markers (HIM), characterized by hyperattenuation on head non-contrast computed tomography immediately after thrombectomy, to predict the risk of hemorrhagic transformation (HT) in patients undergoing endovascular mechanical thrombectomy (MT).
Methods: A total of 159 consecutive patients with HIM were screened immediately after MT for inclusion. The datasets were randomly divided into training and test cohorts at a ratio of 8:2.
The Chinese white pear (Pyrus bretschneideri) is an economically significant fruit crop worldwide. Previous versions of the P. bretschneideri genome assembly contain numerous gaps and unanchored genetic regions.
View Article and Find Full Text PDFPhysiol Mol Biol Plants
February 2025
Single-cell transcriptomics overcomes the limitations of conventional transcriptome methods by isolating and sequencing RNA from individual cells, thus capturing unique expression values for each cell. This technology allows unprecedented precision in observing the stochasticity and heterogeneity of gene expression within cells. However, single-cell RNA sequencing (scRNA-seq) experiments often fail to capture all cells and genes comprehensively, and single-modality data is insufficient to explain cell states and systemic changes.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
January 2025
In this paper, we assess the visualization literacy of two prominent Large Language Models (LLMs): OpenAI's Generative Pretrained Transformers (GPT), the backend of ChatGPT, and Google's Gemini, previously known as Bard, to establish benchmarks for assessing their visualization capabilities. While LLMs have shown promise in generating chart descriptions, captions, and design suggestions, their potential for evaluating visualizations remains under-explored. Collecting data from humans for evaluations has been a bottleneck for visualization research in terms of both time and money, and if LLMs were able to serve, even in some limited role, as evaluators, they could be a significant resource.
View Article and Find Full Text PDFBackground: Malignant cerebral edema (MCE) is a significant complication following endovascular thrombectomy (EVT) in the treatment of acute ischemic stroke. This study aimed to develop and validate a deep learning-assisted diagnosis model based on the hyperattenuated imaging marker (HIM), characterized by hyperattenuation on head non-contrast computed tomography immediately after thrombectomy, to facilitate radiologists in predicting MCE in patients receiving EVT.
Methods: This study included 271 patients, with 168 in the training cohort, 43 in the validation cohort, and 60 in the prospective internal test cohort.
World J Gastrointest Surg
January 2025
Background: Postpancreatectomy hemorrhage is one of the most severe and life-threatening complications after pancreaticoduodenectomy. We present four cases of gastrointestinal bleeding patients to clarify its appropriate treatment and prevention.
Case Summary: The main symptoms included black stool, hematochezia, haematemesis, blood in the nasogastric tube, and hemorrhagic shock.
genes can evolve "from scratch" from noncoding sequences, acquiring novel functions in organisms and integrating into regulatory networks during evolution to drive innovations in important phenotypes and traits. However, identifying genes is challenging, as it requires high-quality genomes from closely related species. According to the comparison with nine closely related genomes, we determined at least 178 genes in "baifeng".
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
September 2024
Biological visual systems have evolved to process natural scenes. A full understanding of visual cortical functions requires a comprehensive characterization of how neuronal populations in each visual area encode natural scenes. Here, we utilized widefield calcium imaging to record V4 cortical response to tens of thousands of natural images in male macaques.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
June 2024
We examine visual representations of data that make use of combinations of both 2D and 3D data mappings. Combining 2D and 3D representations is a common technique that allows viewers to understand multiple facets of the data with which they are interacting. While 3D representations focus on the spatial character of the data or the dedicated 3D data mapping, 2D representations often show abstract data properties and take advantage of the unique benefits of mapping to a plane.
View Article and Find Full Text PDFTransl Pediatr
February 2024
Background: Influenza A is the most common viral pathogen isolated from pediatric clinics during influenza seasons. Some young patients with influenza manifest rapid progression with high fever and severe sequelae, such as pneumonia and meningitis. Therefore, early diagnosis and prompt treatment are highly important.
View Article and Find Full Text PDFThe Chinese white pear (Pyrus bretschneideri) fruit carries a high proportion of stone cells, adversely affecting fruit quality. Lignin is a main component of stone cells in pear fruit. In this study, we discovered that a pear MYB transcription factor, PbMYB80, binds to the promoters of key lignin biosynthesis genes and inhibits their expression.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
April 2024
We visualize the predictions of multiple machine learning models to help biologists as they interactively make decisions about cell lineage-the development of a (plant) embryo from a single ovum cell. Based on a confocal microscopy dataset, traditionally biologists manually constructed the cell lineage, starting from this observation and reasoning backward in time to establish their inheritance. To speed up this tedious process, we make use of machine learning (ML) models trained on a database of manually established cell lineages to assist the biologist in cell assignment.
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