Interleukin-27 Promotes the Generation of Myeloid-derived Suppressor Cells to Alleviate Graft-versus-host Disease.

Background: Stimulation of myeloid-derived suppressor cell (MDSC) formation represents a potential curative therapeutic approach for graft-versus-host disease (GVHD), which significantly impacts the prognosis of allogeneic hematopoietic stem cell transplantation. However, the lack of an effective strategy for inducing MDSC production in vivo has hindered their clinical application. In our previous study, MDSC expansion was observed in interleukin (IL)-27-treated mice.

Simple fluorescence "turn-off" assay for Congo red using commercial 2-aminophthalic acid.

In this work, the fluorescence properties of 2-aminophthalic acid (NH-BDC) were studied. NH-BDC possessed excellent optical properties including bright blue emission with maximum emission at 425 nm, a high quantum yield of 38.49% and excellent photostability.

Improving the surface area of metal organic framework-derived porous carbon through constructing inner support by compatible graphene quantum dots.

Metal-organic frameworks (MOFs) have emerged as promising precursors to prepare porous carbons due to their unique coordination structure with abundant pores and various chemical compositions. However, the structural collapse and pore shrinkage during pyrolysis severely decrease the surface area of the prepared porous carbons. Herein, we propose an inner support strategy to prepare MOF-derived carbons with improved surface area using graphene quantum dots (GQDs) as the compatible frameworks.

Prognostic value of LAT-1 status in solid cancer: A systematic review and meta-analysis.

Background: The expression of the L-type amino acid transporter 1 (LAT1) plays a significant role in tumor progression. However, it remains unclear whether high LAT1 expression correlates with poor prognosis of solid tumor patients. Here, we conducted a meta-analysis to assess the potential of LAT1 in predicting the prognosis of tumor patients.

Graphene Quantum Dot Reinforced Electrospun Carbon Nanofiber Fabrics with High Surface Area for Ultrahigh Rate Supercapacitors.

High surface area, good conductivity, and high mechanical strength are important for carbon nanofiber fabrics (CNFs) as high-performance supercapacitor electrodes. However, it remains a big challenge because of the trade-off between the strong and continuous conductive network and a well-developed porous structure. Herein, we report a simple strategy to integrate these properties into the electrospun CNFs by adding graphene quantum dots (GQDs).

Understanding the structural transformation of carbon black from solid spheres to hollow polyhedra during high temperature treatment.

Understanding the structural transformation of carbon black during high temperature treatment and the underlying mechanism are very important because of the correlation with nanocarbon species such as fullerenes and carbon onions. Herein, we find that carbon black nanoparticles exhibit a solid skin-core structure constructed from small graphene flakes. The skin shows a more ordered structure than the core.

Predicting the Prognosis of Gastric Cancer by Albumin/Globulin Ratio and the Prognostic Nutritional Index.

Albumin-to-globulin ratio (AGR) and the prognostic nutrition index (PNI) are used to assess the nutritional status and severity of disease for a cancer patient. However, the clinical significance of combining these two predictors in gastric cancer (GC) remains unclear. This study evaluated the prognostic value of pretreatment serum AGR and the PNI for GC.

Characterization of two odorant binding proteins in Spodoptera exigua reveals functional conservation and difference.

As the first biochemical step of olfactory reception and recognition, odorant binding proteins (OBPs) have been demonstrated to be essential. Considering functional diversities of OBPs within a single species, we here extended the characterization of two other OBPs from Spodoptera exigua, belonging to insect Classic OBPs. With a combination of transcriptome and Rapid Amplification of cDNA End (RACE) approaches, two OBP genes in S.

Putative pathway of sex pheromone biosynthesis and degradation by expression patterns of genes identified from female pheromone gland and adult antenna of Sesamia inferens (Walker).

The general pathway of biosynthesis and degradation for Type-I sex pheromones in moths is well established, but some genes involved in this pathway remain to be characterized. The purple stem borer, Sesamia inferens, employs a pheromone blend containing components with three different terminal functional groups (Z11-16:OAc, Z11-16:OH, and Z11-16:Ald) of Type-I sex pheromones. Thus, it provides a good model to study the diversity of genes involved in pheromone biosynthesis and degradation pathways.