Consumption of ultra-processed foods raises the possibility of cardiovascular disease - A meta-analysis.

Aim: the purpose of this study was to assess the connection among ultra-processed food consumption and the likelihood of cardiovascular disease, with the intention of establishing a basis for future research.

Methods: this meta-analysis adheres to the reporting principles recommended in the PRISMA framework. PubMed, Embase, and Web of Science bibliographic databases were searched in January 2023.

Application of Amorphous and Nanocrystalline Soft Magnetic Materials in Balanced-Force-Type Electromagnetic Relay.

The magnetic properties of soft magnetic materials, including their saturation magnetic induction strength and permeability, significantly affect the dynamic characteristics of electromagnetic relays. However, the soft materials most commonly used for relays in the magnetic conductive components of electromagnetic systems, such as electrical pure iron, limit further relay design improvement and optimization to a certain extent. Thus, this paper proposes the use of amorphous and nanocrystalline soft magnetic materials with good high-frequency magnetic properties in magnetic circuits.

The role of retinal glial cells and related factors in macular edema.

Macular edema (ME) has emerged as a leading cause of visual impairment, representing a critical clinical manifestation and complication associated with many eye diseases. In the occurrence and development of ME, retinal glial cells like Müller cells and microglial cells play vital roles. Moreover, growth factor and cytokines associated with them, such as vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), hypoxia-inducible factor-1α (HIF-1α), angiopoietin-like protein 4 (ANGPTL4), interleukin-6(IL-6), interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1), prostaglandin, etc.

GTransU-CAP: Automatic labeling for cyclic alternating patterns in sleep EEG using gated transformer-based U-Net framework.

Cyclic alternating pattern (CAP) sequences are composed of cycles of alternate activation phases (A-phases) and background phases. CAP A-phases can be further divided into three subtypes, which act as important bio-markers of sleep instability and are also associated with identifiable sleep pathologies. Thus, its accurate detection and identification is of great clinical interest and significance.

SpindleU-Net: An Adaptive U-Net Framework for Sleep Spindle Detection in Single-Channel EEG.

The sleep spindles in EEG have become one type of biomarker used to assess cognitive abilities and related disorders, and thus their detection is crucial for clinical research. This task, traditionally performed by sleep experts, is time-consuming. Many methods have been proposed to automate this process, yet an increase in performance is still expected.

Multiple Bioinformatics Analyses of Integrated Gene Expression Profiling Data and Verification of Hub Genes Associated with Diabetic Retinopathy.

BACKGROUND Diabetic retinopathy (DR) is a serious complication of diabetes that can lead to blindness. This study aimed to identify the core genes and molecular functions involved in DR through multiple bioinformatics analyses. MATERIAL AND METHODS The mRNA gene profiles of human DR tissues from the GSE60436 and GSE53257 datasets were assessed with R software and integrated to identify the co-expressed differentially expressed genes (DEGs).

Autophagy, lysosome dysfunction and mTOR inhibition in MNU-induced photoreceptor cell damage.

Progressive photoreceptor death is the main cause of retinal degeneration diseases. Determining the underlying mechanism of this process is essential for therapy improvement. Autophagy has long been considered to be involved in neuronal degeneration diseases, and the regulation of autophagy is thought to have potential implications for neurodegenerative disease therapies.

Production of xylooligosaccharides and monosaccharides from hydrogen peroxide-acetic acid-pretreated poplar by two-step enzymatic hydrolysis.

The severe pretreatment of poplar makes xylan difficult to utilize efficiently. In this work, poplar was pretreated by hydrogen peroxide-acetic acid (HPAC) with HSO as catalyst to remove lignin, and the solid residues were used to produce xylooligosaccharides (XOS) and monosaccharides by two-step xylanase and cellulase hydrolysis. The results indicated that higher HSO concentrations in the HPAC pretreatment of poplar afforded stronger lignin removal ability.