High-entropy doping in NASICON cathodes: Activating the V/V redox couple and inducing a reversible single solid-solution phase reaction for advanced sodium ion batteries.

NaV(PO) (NVP) with typical NASICON structure is highly regarded as one of the most appealing cathodes for sodium-ion batteries (SIBs) for their excellent structural stability; however, the poor electronic conductivity and irreversible phase transition at high voltage (∼4 V) for the material result in poor rate capabilities and significant capacity degradation during electrochemical reactions. Herein, the high-entropy doping strategy of introducing six types of metal ions into the V-sites in NaV(PO) is used to design a high-performance cathode of NaV(Mn, Ca, Mg, Al, Zr)Nb(PO) (HE-NVP) for SIBs. After the high-entropy doping, a reversible V/V redox pair is activated at high voltage of ∼4 V, which significantly contributes to the enhancement of energy density and operating voltage.

Tribological metamaterial: how feathers reduce drag and friction through hidden energy dissipation structures.

The lateral moving resistance of a liquid droplet on a solid surface generally increases with velocity and is dominated by the non-viscous wetting line friction. Many superhydrophobic man-made and biological surfaces have minimal, nevertheless speed-sensitive, water droplet friction, limiting their potential to reduce drag at high speeds in natural situations. Using an surface force apparatus, we demonstrated low and remarkably speed-insensitive (over 300-fold) water bridge sliding friction on a goose feather vane.

Effect of dexmedetomidine on postoperative delirium in patients undergoing type A aortic dissection surgery: a prospective cohort study.

Background: Postoperative delirium (POD) is a common neurocognitive complication after type A aortic dissection (TAAD), which seriously affects the recovery of patients, and the current intervention timing and treatment methods are still uncertain. This prospective observational cohort study aimed to discuss the effect of dexmedetomidine on POD in patients undergoing TAAD surgery.

Methods: Between February 2022 and March 2023, 167 eligible patients aged 18 to 85 years who underwent TAAD surgery participated in this study.

Comparison of fluoride level between mother's milk and infant formula milk - a global systematic review and dental fluorosis risk assessment.

Dental Fluorosis (DF) is one of the negative outcomes of excessive fluoride (F) intake through food sources. This systematic review aimed to compare F content in two important food sources for infants, Mother's Milk (MoM) and Infant Formula (IF), and then evaluate the risk of DF related to F in those two types of food. For this purpose, 181 studies were initially found by searching the relevant keywords in widely recognized databases, including Google Scholar, Scopus, Science Direct, and PubMed.

5,7-Dihydroxyflavone acts on eNOS to achieve hypotensive effects in spontaneously hypertensive rats.

Hypertension is one of the most serious chronic diseases. This study will focus on the systemic antihypertensive mechanisms of 5,7-dihydroxyflavone from in silico simulations to in vivo validations. In-silico studies were applied by network pharmacology, molecular docking, and molecular dynamic simulation.

Coronary artery bypass grafting in dialysis patients: a propensity score-matched analysis.

Background: Patients undergoing dialysis treatment have long been recognized as having an elevated risk of developing coronary artery disease necessitating coronary artery bypass grafting (CABG). However, the prognostic implications of CABG in dialysis-dependent patients remain underexplored. This study aimed to comprehensively assess both short- and long-term outcomes in dialysis-dependent patients undergoing CABG.

Significant lead isotope 'fractionation' in maize records plant lead uptake, transfer, and detoxification mechanisms.

Lead isotope analysis is the main method to trace the sources and cycling of Pb in the biosphere system. The linchpin of such application hinges on the assumption that there is negligible or no biologically mediated isotopic fractionation of Pb occurs in the environment. However, recent measurements by high-precision multi-collector mass spectrometry revealed that biological isotope fractionation of heavy mass elements is a prevalent phenomenon.

New magnetic proxies to reveal source and bioavailability of heavy metals in contaminated soils.

Environmental magnetism plays an important role in monitoring heavy metal pollution, but most studies are confined to indicating only the levels of heavy metals using magnetic parameters. This study established new magnetic proxies for accurately depicting the sources and bioavailability of heavy metals in contaminated soils. We observed different relationships between χ and SIRM in the soils contaminated by non-ferrous metal smelting compared to those polluted by coal combustion and steel smelting.

Meta-analysis of the adoption of omalizumab in the treatment of pediatric allergic diseases.

Introduction: Allergic diseases are common chronic conditions in children, omalizumab has a wide range of adoptions in various diseases. A meta-analysis was implemented to demonstrate the efficacy of omalizumab in the therapy of pediatric allergic diseases.

Materials And Methods: English databases were searched.

Knowledge, attitudes, and practices towards Kawasaki disease from caregivers of children with Kawasaki disease: a cross-sectional study.

Purpose: To examine the knowledge, attitudes, and practices (KAP) of caregivers of children with Kawasaki disease toward Kawasaki disease.

Methods: This cross-sectional study was conducted at four hospitals in China from March 2023 to June 2023. The KAP scores were evaluated using a self-designed questionnaire (Cronbach's α = 0.

Application and development of a TaqMan-based real-time PCR assay for rapid detection of snakehead vesiculovirus.

Snakehead vesiculovirus (SHVV) is one of the primary pathogens responsible for viral diseases in the snakehead fish. A TaqMan-based real-time PCR assay was established for the rapid detection and quantification of SHVV in this study. Specific primers and fluorescent probes were designed for phosphoprotein (P) gene, and after optimizing the reaction conditions, the results indicated that the detection limit of this method could reach 37.

Increasing tropical cyclone intensity in the western North Pacific partly driven by warming Tibetan Plateau.

The increase in intense tropical cyclone (TC) activity across the western North Pacific (WNP) has often been attributed to a warming ocean. However, it is essential to recognize that the tropical WNP region already boasts high temperatures, and a marginal increase in oceanic warmth due to global warming does not exert a significant impact on the potential for TCs to intensify. Here we report that the weakened vertical wind shear is the primary driver behind the escalating trend in TC intensity within the summer monsoon trough of the tropical WNP, while local ocean surface and subsurface thermodynamic factors play a minor role.

Origin traceability of Cordyceps sinensis based on trace elements and stable isotope fingerprints.

Cordyceps sinensis is a kind of valuable Chinese herbal medicine, and its quality and price depend on the place of origin. Building a traceability system for Cordyceps sinensis products is an effective way to protect Cordyceps sinensis geographical indication products and consumers. In this study, concentrations of 45 trace elements and stable C, N, and Pb isotopes were used to distinguish Cordyceps sinensis samples from different habitats and different varieties (natural and artificial).

Exosomal EIF5A derived from Lewis lung carcinoma induced adipocyte wasting in cancer cachexia.

Cancer cachexia is a systemic inflammation-driven syndrome, characterized by muscle atrophy and adipose tissue wasting, with progressive weight loss leading to serious impairment of physiological function. Extracellular vesicles (EVs) derived from cancer cells play a significant role in adipocyte lipolysis, yet the mechanism remain uneclucidated. In this study, EVs derived from Lewis lung carcinoma (LLC) cells were extracted and characterized.

The Prognostic Value of Johns Hopkins Hospital Nutrition Support Score in Older Patients Undergoing Cardiovascular Surgery.

Objectives: Clarify the prognostic value of the Johns Hopkins Hospital Nutrition Support (JHHNS) score on clinical outcomes in older patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB).

Design: A retrospective observational study.

Setting: A teaching and university hospital and tertiary referral center.

Gas-to-ionic liquid partition: QSPR modeling and mechanistic interpretation.

The present work was devoted to explore the quantitative structure-property relationships for gas-to-ionic liquid partition coefficients (log K ). A series of linear models were first established for the representative dataset (IL01). The optimal model was a four-parameter equation (1Ed) consisting of two electrostatic potential-based descriptors ( and V ), one 2D matrix-based descriptor (J_D/Dt) and dipole moment (μ).

LncRNA CASC2 Regulate Cell Proliferation and Invasion by Targeting miR-155/SOCS1 Axis in Hepatocellular Carcinoma.

Long noncoding RNAs (lncRNAs) have been reported to be involved in the development and progression of various human malignancies. However, the role of lncRNA CASC2 in hepatocellular carcinoma (HCC) remains mostly unknown. The aim of this study was to investigate the potential roles and underlying mechanisms of CASC2 in HCC progression.

Spatial Distribution, Pollution, and Ecological Risk Assessment of Metal(loid)s in Multiple Spheres of the Shennongjia Alpine Critical Zone, Central China.

The development of Earth's critical zone concept has strengthened the capacity of environmental science to better solve real-world problems, such as metal(loid) pollution in the remote alpine areas. The selected metal(loid) contents in soil, moss, and water were investigated to explore the geochemical distribution patterns, pollution levels, and potential ecological risks of metal(loid)s in the Shennongjia (SNJ) alpine critical zone of central China. The distribution of metal(loid)s in different spheres had horizontal and vertical differences.

Application of Pb Isotopes and REY Patterns in Tracing Heavy Metals in Farmland Soils from the Upper-Middle Area of Yangtze River.

Farmland heavy metal pollution-caused by both human activity and natural processes-is a major global issue. In the current study, principal component analysis (PCA), cluster analysis (CA), rare earth elements and yttrium (REY) analysis, and isotope fingerprinting were combined to identify sources of heavy metal pollution in soil from different farmland types in the upper-middle area of the Yangtze River. The concentrations of Zn and Cu were found to be higher in the vegetable base and tea plantation soil compared with their concentrations in the orangery soil.

Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway.

Background: Cytokines secreted in the tumor microenvironment function in cancer cachexia (CC), a common clinicopathological syndrome associated with adipocyte wasting and skeletal muscle atrophy. Extracellular vesicles (EVs) secreted by cancer cells actively engage in inter-tissue communication; EVs and enclosed cytokines are largely undefined in CC adipocytes wasting.

Methods: EVs derived from Lewis lung carcinoma (LLC) and colorectal cancer C26 cells were extracted and characterized.

Ascorbic acid-induced fiber-scrolling of titanium carbide TiCT MXene.

Changing the morphology of two-dimensional materials often offers an efficient and effective means to exploit their electronic and mechanical properties. Two-dimensional materials such as graphene can be scrolled into one-dimensional fibers simple sonication. Unfortunately, scrolling MXene nanosheets into fibers is quite challenging, especially TiCT composed of three layers of titanium atoms and two layers of carbon atoms.

Characterization of the pathogenesis and immune response to a highly virulent Edwardsiella tarda strain responsible for mass mortality in the hybrid snakehead (Channa maculate ♀ × Channa argus ♂).

Edwardsiella tarda is reported as the causative agent of the systemic disease Edwardsiellosis in fish, which lead to huge economic losses in aquaculture. The pathogenicity and immune response to a highly virulent E. tarda isolate responsible for mass mortality in hybrid snakehead were performed.

Circular RNA circ-RCCD promotes cardiomyocyte differentiation in mouse embryo development via recruiting YY1 to the promoter of MyD88.

Congenital heart disease (CHD) is the most common birth defect, affecting approximately 1% of live births. Genetic and environmental factors are leading factors to CHD, but the mechanism of CHD pathogenesis remains unclear. Circular RNAs (circRNAs) are kinds of endogenous non-coding RNAs (ncRNAs) involved in a variety of physiological and pathological processes, especially in heart diseases.