Robust Luminescent Pyrene-Based Metal-Organic Framework Hydrogel as a pH-Responsive Fluorescence Emitter for Sensitive Immunoassay of Cardiac Troponin I.

Despite many luminescent advantages including outstanding absorption coefficient and high quantum yield, pyrene and its derivatives have been suffering from a dramatic aggregation-caused quenching (ACQ) effect. Although the dramatic ACQ effect of pyrene-based fluorophores has been restrained in pyrene-doped metal-organic frameworks (MOFs), the low loading of fluorescent (FL) units substantially impedes the improved luminescent behaviors. Herein, pyrene-based MOFs hydrogel was synthesized with a high loading of pyrene as the unique organic linker blocks instead of a dopant in MOFs.

Design and Synthesis of Mandelic Acid Derivatives for Suppression of Virulence T3SS against Citrus Canker.

Citrus canker, a highly contagious bacterial disease caused by subsp. (), poses a substantial threat to citrus crops, leading to serious reductions in fruit yield and economic losses. Most commonly used bactericides against lead to the rapid development of resistant subpopulations.

Layer Growth Inhibiting Strategy for Superior-Loading Atomic Metal Sites on Ultrathin Layered Double Hydroxides as the Efficient Chemiluminescence Probes.

Owing to the remarkable catalytic attributes, single-atom catalysts (SACs) have exhibited promising application prospects as the substitutes of natural enzymes. However, the low loading amount of atomic sites on typical SACs (no more than 5 wt %) significantly restricts their increased capability. Hereby, a layer growth inhibitor protocol was attempted to optimize anchoring isolated Co atoms efficiently on ultrathin monolayer layered double hydroxides (LDHs).

CoN-supported CoN metal clusters for developing sensitive chemiluminescent immunochromatographic assays.

In view of the optimal catalytic efficiency (∼100%), single-atom site catalysts are being widely exploited in a range of areas including organic synthesis, energy conversion, environmental remediation, biotherapy, etc. However, low loading ratio of the unitary active sites on single-atom site catalysts dramatically hinders the remarkable improvement of their catalytic activity. Hereby, a facile low-temperature reduction protocol was adopted for synthesizing CoN-supported CoN metal clusters on graphitic carbon nitride, which show the remarkably superior chemiluminescent (CL) catalytic capacity than some reported pure single-atom site catalysts.

Defective Site Modulation Strategy for Preparing Single Atom-Dispersed Catalysts as Superior Chemiluminescent Signal Probes.

Single atom-dispersed catalysts (SADCs) with highly exposed active sites can be used as sensitive signal probes because of their superior catalytic efficiency. However, the dispersed atoms tend to aggregate, restricting the loading capacity of metal atoms. Herein, the defective sites on Zr-oxo clusters of metal-organic frameworks (MOFs) UiO-66-NH were modulated by excessive acetic acid and utilized for confining metal atoms with high loading capacity.

Synergetic Dual-Site Atomic Catalysts for Sensitive Chemiluminescent Immunochromatographic Test Strips.

In view of the outstanding catalytic efficiency, single-atom catalysts (SACs) have shown great promise for the construction of sensitive chemiluminescent (CL) platforms. However, the low loading amount of active sites dramatically obstructs the improved catalytic activity of these metal SACs. Benefiting from the exceedingly unique catalytic properties of the metal-metal bonds, atomic clusters may give rise to enhancing the catalytic properties of SACs based on the synergistic effects of dual atomic-scale sites.

Highly Sensitive Chemiluminescent Immunoassay of Mycotoxins Using ZIF-8-Derived Yolk-Shell Co Single-Atom Site Catalysts as Superior Fenton-like Probes.

Superior to traditional nanoscale catalysts, single-atom site catalysts (SASCs) show such merits as maximal catalysis efficiency and outstanding catalytic activity for the construction of analytical methodological platforms. Hereby, an in situ etching strategy was designed to prepare yolk-shell Co SASCs derived from ZIF-8@SiO nanoparticles. On the basis of direct chemical interactions between precursors and supports, the Co element with isolated atomic dispersion was anchored on ZIF-8@SiO nanoparticles.

Emitter-Quencher Pair of Single Atomic Co Sites and Monolayer Titanium Carbide MXenes for Luminol Chemiluminescent Reactions.

A facile, one-step doping protocol was adopted to synthesize Co single atomic site catalysts (SASCs) in UiO-66 metal-organic frameworks. In view of highly uniform active sites of Co-O moieties, the SASCs specifically contribute to catalyzing the generation of a large amount of singlet oxygen instead of superoxide or hydroxyl radicals, which endows Co SASCs with a the remarkable enhancement effect (∼3775 times) on luminol chemiluminescent (CL) emission. Interestingly, monolayer titanium carbide MXenes can drastically quench the CL signal of the Co SASC-boosted luminol reaction by ∼94.