Discovering the antibacterial activity of tryptanthrin derivatives for controlling kiwifruit canker and tobacco wilt disease.

Background: Plant bacterial diseases have severely affected the yield and quality of agricultural products, among which kiwifruit canker and bacterial wilt disease, caused by Pseudomonas syringae pv. actinidiae (Psa) and Ralstonia solanacearum (Rs), respectively, seriously restrict the development of the related industry. However, there are few effective green agents available to target these diseases.

Strengths, weaknesses, opportunities, and threats analysis of combination therapy for inflammatory bowel disease.

Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, manifests as a chronic, recurrent, and refractory intestinal inflammatory condition significantly impacting patients' quality of life. Despite ongoing research, its etiology and pathogenesis remain incompletely understood. Recent advancements in medical research highlight the critical role of drug combination therapies in managing IBD.

Tuina alleviates the muscle atrophy induced by sciatic nerve injury in rats through regulation of PI3K/Akt signaling.

Background: Tuina is an effective treatment for the decrease of skeletal muscle atrophy after peripheral nerve injury. However, the underlying mechanism of action remains unclear. This study aimed to explore the underlying mechanisms of tuina in rats with sciatic nerve injury (SNI).