Publications by authors named "Jiarui Guo"

Article Synopsis
  • This study investigates the relationship between changes in microbial communities in the lungs and gut of a rat model for idiopathic pulmonary fibrosis (IPF) to understand how these changes may relate to disease mechanisms.
  • Researchers found significant differences in microbial composition in the lung and gut of IPF model rats when compared to control rats, indicating a potential link between microbial shifts and IPF.
  • Mediation analysis identified specific physiological indices, such as hydroxyproline and mean corpuscular volume, that connect lung and gut microbial genera, revealing complex interactions that could contribute to IPF pathology through the "gut-lung axis."
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All-inorganic metal halide perovskites (MHPs) have attracted increasing attention because of their high thermal stability and band gap tunability. Among them, CsPbCl is considered a promising semiconductor material for visible-ultraviolet dual-band photodetectors because of its excellent photoelectric properties and suitable band gap value. In this work, we fabricated a visible-ultraviolet dual-band photodetector based on a CsPbCl/p-GaN heterojunction using the spin coating method.

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  • Varicose veins (VV) are a widespread venous disease that affects patients' quality of life and places a financial strain on healthcare systems, prompting a study to identify genes and drug targets for treatment.
  • The research utilized Mendelian randomization and other statistical analyses on genetic data, ultimately screening 12 candidate genes to find four with significant causal links to VV.
  • The identified genes display varying relationships with the disease, with three associated with an increased risk and one linked to a decreased risk, suggesting potential targets for future VV therapies.
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Solar-blind photodetectors based on wide bandgap semiconductors have recently attracted a lot of interest. Nickel-containing spinel phase oxides, such as NiAlO, are stable p-type semiconductors. This paper describes a multifunctional solar-blind photodetector based on a NiAlO/4H-SiC heterojunction that utilizes photovoltaic effects.

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Cholesterol homeostasis is crucial for cellular and systemic function. The disorder of cholesterol metabolism not only accelerates the onset of cardiovascular disease (CVD) but is also the fundamental cause of other ailments. The regulation of cholesterol metabolism in the human is an extremely complex process.

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  • Congenital cataract, primarily caused by crystallin mutations, is a significant contributor to childhood blindness, with over 40% of cases linked to gene mutations.
  • The research identified a novel R114C mutation in a Chinese family causing bilateral cataract and found that this mutation affects the structural integrity and solubility of βA3-crystallin, making it more susceptible to environmental stresses like UV and heat.
  • The study highlights how the R114C mutation disrupts hydrogen bonds and structural stability, providing insights into the mechanisms of cataract formation and potentially guiding future treatment developments.
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Two-dimensional (2D) organic-inorganic hybrid perovskites (OIPs) have exhibited ideal prospects for perovskite photodetectors (PDs) owing to their remarkable environmental stability, tunable band gap, and structural diversity. However, most perovskites face the great challenge of a narrow spectral response. Integrating 2D OIPs with a suitable wide band gap semiconductor gives opportunities to broaden the response spectra.

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We have designed a metal-semiconductor-metal (MSM) solar-blind ultraviolet (UV) photodetector (PD) by utilizing AlGaN/AlGaN/AlGaN heterostructures. The interdigital Ni/Au metal stack is deposited on the AlGaN layer to form Schottky contacts. The AlGaN hetero-epilayers with varying Al content contribute to the formation of a two-dimensional electron gas (2DEG) conduction channel and the enhancement of the built-in electric field in the AlGaN absorption layer.

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Objective: To investigate the effect of body mass index (BMI) on the short-term effectiveness of high tibial osteotomy (HTO) in the treatment of varus knee arthritis.

Methods: The clinical data of 84 patients (84 knees) with varus knee arthritis treated with HTO between May 2016 and August 2020 were retrospectively analyzed. According to BMI, the patients were divided into normal group (32 patients in group A, BMI<25 kg/m ), overweight group (27 patients in group B, BMI>30 kg/m ), and obese group (25 patients in group C, BMI>30 kg/m ).

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Objective: To investigate the effectiveness of a novel lateral tibial plateau annular plate (hereinafter referred to as the novel plate) fixation via fibular neck osteotomy approach for posterolateral tibial plateau fractures.

Methods: Between January 2015 and December 2018, 22 patients with posterolateral tibial plateau fractures were treated. There were 10 males and 12 females with an average age of 39.

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Membrane fouling markedly influences the service life and performance of the membrane during the using process. Herein, hydrophilic polyvinylidene fluoride (PVDF) nanocomposite (P-GO-DAA) membranes with antifouling and anti-biofouling characteristics were fabricated by employing graphene oxide (GO) and different concentrations of D-Tyrosine. The structural properties of the prepared nanocomposite membranes as well as pure PVDF membranes were characterized using FTIR, XPS, SEM, AFM, and contact angle analysis.

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Article Synopsis
  • The ability to create 2D and 3D metallic structures using low melting point metals like gallium has significant implications for flexible electronics, displays, sensors, and antennas due to its excellent electrical properties.
  • Challenges in 3D printing gallium arise from its high surface tension and density, making large-scale production difficult.
  • The article introduces a novel electrochemically enabled embedded 3D printing method (3e-3DP) that allows for the creation of freestanding gallium structures and demonstrates its application in making flexible conductors and pressure sensors, offering a cost-effective solution for future electronics.
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  • The study introduces a magnetic liquid metal droplet (MLMD) that can stretch both horizontally and vertically in free space, made from a combination of liquid metals, iron particles, and electrolytes.
  • This droplet exhibits unique properties such as reversible and long-lasting stretching, with its strength attributed to a surface oxide layer, enabling it to act as an intelligent scalable conductor for electrical connections in 3D space.
  • The MLMD mimics the movement of upright walking amphibians, allowing for precise and contactless control via magnetic fields, suggesting future applications in dynamic soft robotics and multi-freedom actuation.
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N-heterocyclic carbene-palladium(ii)-catalyzed cross-coupling of benzylammonium salts with arylboronic acids for the synthesis of diarylmethane derivatives C-N bond activation has been developed. Notably, in the presence of the easily prepared and bench-stable Pd-PEPPSI precatalyst, the Csp-N bond activation of the benzylammonium salt even proceeded smoothly in isopropanol at room temperature.

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In this study, an electric field was used to regulate and control pseudopodia-like extensions of a liquid metal-Al (LM-Al) droplet in certain directions. The results suggest that in certain electric fields, the LM-Al droplets tend to generate extensions perpendicular to the electric field; the underlying mechanism arises from the specific surface tension imbalance induced by the electric field. The influence of varying electric field intensity and Al content on the LM-Al transformations was also evaluated; the LM-Al droplets displayed specific and distinct behaviors according to each experimental configuration; this further proved the feasibility of using electric fields for controlling LM-Al transformations.

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A novel pillar-layer porous lanthanide metal-organic framework [Tb(ODA)(BPDC)Na]·G (UTSA-222, G = guest molecules) was constructed from an organic ligand [1,1'-biphenyl]-4,4'-dicarboxylate (BPDC) and a lanthanide metalloligand [Tb(ODA)] (HODA = oxydiacetic acid). The UTSA-222 contains two-dimensional intersecting channels with the Brunauer-Emmett-Teller surface area and pore volume of 703 m g and 0.344 cm g, respectively, for the activated sample.

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To assess whether global and regional myocardial strains from three-dimensional speckle tracking echocardiography (3D-STE) correlate with myocardial infarction size (MIS) detected by single photon emission computed tomography (SPECT). Fifty-seven patients with a history of ST-segment elevation myocardial infarction (MI) within 3-6 months were enrolled, alongside 24 healthy volunteers. Left ventricular (LV) global area strain, global longitudinal strain (GLS), global radial strain, global circumferential strain, left ventricular ejection fraction (LVEF) and wall motion score index (WMSI) were measured and compared with the corresponding SPECT-detected MISs.

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Synopsis of recent research by authors named "Jiarui Guo"

  • - Jiarui Guo's recent research encompasses advancements in both photodetector materials and healthcare applications, demonstrating a strong focus on harnessing novel materials like metal halide perovskites and nickel-containing oxides for efficient photodetection across various wavelengths, as seen in articles about dual-band and solar-blind photodetectors.
  • - Additionally, Guo has explored biomedical applications, particularly identifying potential drug targets for chronic venous conditions such as varicose veins, merging genetic analysis with clinical data to uncover pathogenic mechanisms and treatment options.
  • - His work also investigates the impact of biochemical factors, such as cholesterol metabolism, on disease emergence, emphasizing the complexity of physiological regulation and its implications for populations prone to cardiovascular conditions.