Publications by authors named "Jiaqin Gao"
Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global health. It is a critical pre‑stage condition of severe hepatopathy, characterized by excessive accumulation of extracellular matrix components and ongoing chronic inflammation. To date, early prevention of liver fibrosis remains challenging.
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- Viral infections pose a significant global health threat, causing hundreds of thousands of deaths each year; understanding the viral replication and infection processes is key to developing new control strategies.
- Long non-coding RNAs (lncRNAs) play essential roles in both viral reproduction and the host's immune response, with many host lncRNAs aiding antiviral efforts during infections.
- However, research on lncRNAs expressed by viruses is still limited, despite their involvement in the viral life cycle and ability to enhance viral pathogenicity, suggesting a need for further exploration to identify these viral lncRNAs as potential therapeutic targets.