Identification of Candidate Genes for Hypoxia Tolerance in Rice by Genome-Wide Association Analysis and Transcriptome Sequencing.

Direct-seeded rice has gained increasing popularity due to its advantage of lower labor costs. Flooding/hypoxia is an important abiotic stress with severe negative impacts on the germination and emergence of direct-seeded rice. Hence, improving the hypoxic germination tolerance of rice is an important way to promote the further development of direct-seeded rice.

A remarkable and durable response to tislelizumab treatment of an anaplastic thyroid carcinoma without targetable genomic alterations: a case report.

Anaplastic thyroid carcinoma (ATC) is a rare and highly aggressive malignancy characterized by a poor prognosis, with a median survival time of approximately 3 to 4 months. In this report, we present a case involving a 59-year-old patient diagnosed with ATC, who experienced swift local recurrence and pulmonary metastasis following radical thyroidectomy. Comprehensive Sanger sequencing of the resected tumor tissue revealed no mutations in the TERT promoter or the BRAF V600E gene.

The Inflammatory Mechanism of Parkinson's Disease: Gut Microbiota Metabolites Affect the Development of the Disease Through the Gut-Brain Axis.

Parkinson's disease is recognized as the second most prevalent neurodegenerative disorder globally, with its incidence rate projected to increase alongside ongoing population growth. However, the precise etiology of Parkinson's disease remains elusive. This article explores the inflammatory mechanisms linking gut microbiota to Parkinson's disease, emphasizing alterations in gut microbiota and their metabolites that influence the disease's progression through the bidirectional transmission of inflammatory signals along the gut-brain axis.

A Green Computing Business Aggregation Strategy for Low Earth Orbit Satellite Networks.

This paper proposes a green computing strategy for low Earth orbit (LEO) satellite networks (LSNs), addressing energy efficiency and delay optimization in dynamic and energy-constrained environments. By integrating a Markov Decision Process (MDP) with a Double Deep Q-Network (Double DQN) and introducing the Energy-Delay Ratio (EDR) metric, this study effectively quantifies and balances energy savings with delay costs. Simulations demonstrate significant energy savings, with reductions of up to 47.

Agent-based simulation of trust networks and opportunistic behaviours of hydraulic infrastructure project participants.

Opportunistic behaviour has become a research hotspot in hydraulic infrastructure project management owing to its serious damage to the cooperation efficiency of all participants in a project. The trust networks formed by each participant can restrain opportunistic behaviour, but due to the dynamic evolution of the networks, its research should adopt a dynamic paradigm. The structure and evolution of trust networks can be simulated using computer simulations and modelling.

Genome-wide identification of rice gene family and mining of alleles for potential application in rice improvement.

Carboxylesterases (CXE, EC 3.1.1.

Two-temperature thermochemical nonequilibrium model based on the coarse-grained treatment of molecular vibrational states.

Although the high-fidelity state-to-state (StS) model accurately describes high-temperature thermochemical nonequilibrium flows, its practical application is hindered by the prohibitively high computational cost. In this paper, we develop a reduced-order model that leverages the widely used two-temperature (2T) framework and a coarse-grained treatment of molecular vibrational states to achieve accuracy comparable to the StS model while ensuring computational efficiency. We observe that the multigroup coarse-grained model (CGM), lumping vibrational energy levels into several groups, yields results close to the StS model for the high-temperature postshock oxygen flows, even using only two groups.

Analysis of the Rice Raffinose Synthase (OsRS) Gene Family and Haplotype Diversity.

Based on the genome information of rice (Nipponbare), this study screened and identified six raffinose synthase (RS) genes and analyzed their physical and chemical properties, phylogenetic relationship, conserved domains, promoter cis-acting elements, and the function and genetic diversity of the gene-CDS-haplotype (gcHap). The results showed that these genes play key roles in abiotic stress response, such as , whose expression in leaves changed significantly under high salt, drought, ABA, and MeJA treatments. In addition, the OsRS genes showed significant genetic variations in different rice populations.

Drug Use Behaviors and the Risk of HIV Infection Among Drug Users in China Between 2014 and 2021: Cross-Sectional Study.

Background: Drug users are a high-risk group for HIV infection and are prominent HIV carriers. Given the emergence of new drugs, we explored current drug-using behaviors, HIV infections, and the correlation between drug-using behaviors and HIV infection risk among drug users from 2014 to 2021.

Objective: We aimed to identify the prevalence of HIV infection risk among drug users and explore drug use behaviors based on the updated data, which could provide evidence for the precision of HIV prevention strategies among drug users.

Quantification and visual inspection of adipic dihydrazide in textile using a xanthylium-based ratiometric fluorescent probe.

Residual adipic dihydrazide (ADH) in textiles may react with formaldehyde to form hydrazone, which is a source of the formaldehyde pollutant indoors. In this paper, a xanthylium-based ratiometric fluorescent probe SH-Py was developed for ADH detection. The emission of SH-Py at 680 nm decreased, whereas that at 463 nm increased upon the addition of ADH in pure DMSO.

Tuning Iron Active Sites of FeOOH via Al and Heteroatom Doping-Induced Asymmetric Oxygen Vacancy Electronic Structure for Efficient Alkaline Water Splitting.

Oxygen evolution reaction is the essential anodic reaction for water splitting. Designing tunable electronic structures to overcome its slow kinetics is an effective strategy. Herein, the molecular ammonium iron sulfate dodecahydrate is employed as the precursor to synthesize the C, N, S triatomic co-doped Fe(Al)OOH on Ni foam (C,N,S-Fe(Al)OOH-NF) with asymmetric electronic structure.

Fast detection of sodium dithionite in sugar using a xanthylium-based fluorescent probe.

Dithionite remained in the foodstuff may pose a great threat to the health of consumers. Three xanthylium-based probes were synthesized and their responses to dithionite were explored. Probe SH-1 could respond to dithionite selectively in PBS buffer (15% DMSO, 10 mM, pH = 7.

Sludge dewaterability improvement with microbial fuel cell powered electro-Fenton system (MFCⓅEFs): Performance and mechanisms.

Throughout the entire process of sludge treatment and disposal, it is crucial to explore stable and efficient techniques to improve sludge dewaterability, which can facilitate subsequent resource utilization and space and cost savings. Traditional Fenton oxidation has been widely researched to enhance the performance of sludge dewaterability, which was limited by the additional energy input and the instabilities of Fe and HO. To reduce the consumption of energy and chemicals and further break the rate-limiting step of the iron cycle, a novel and feasible method that constructed microbial fuel cell powered electro-Fenton systems (MFCⓅEFs) with ferrite and biochar electrode (MgFeO@BC/CF) was successfully demonstrated.

Identification and Regulation of Hypoxia-Tolerant and Germination-Related Genes in Rice.

In direct seeding, hypoxia is a major stress faced by rice plants. Therefore, dissecting the response mechanism of rice to hypoxia stress and the molecular regulatory network is critical to the development of hypoxia-tolerant rice varieties and direct seeding of rice. This review summarizes the morphological, physiological, and ecological changes in rice under hypoxia stress, the discovery of hypoxia-tolerant and germination-related genes/QTLs, and the latest research on candidate genes, and explores the linkage of hypoxia tolerance genes and their distribution in indica and japonica rice through population variance analysis and haplotype network analysis.

Recent Advances in Fluorescent Nanoprobes for Food Safety Detection.

Fluorescent nanoprobes show similar fluorescence properties to traditional organic dyes, but the addition of nanotechnology accurately controls the size, shape, chemical composition, and surface chemistry of the nanoprobes with unique characteristics and properties, such as bright luminescence, high photostability, and strong biocompatibility. For example, modifying aptamers or antibodies on a fluorescent nanoprobe provides high selectivity and specificity for different objects to be tested. Fluorescence intensity, life, and other parameters of targets can be changed by different sensing mechanisms based on the unique structural and optical characteristics of fluorescent nanoprobes.

Constructing Oxygen Vacancies via Engineering Heterostructured Fe C/Fe O Catalysts for Electrochemical Ammonia Synthesis.

Electrocatalytic nitrogen reduction reaction (NRR) under ambient conditions provides an intriguing pathway to convert N into NH . However, significant kinetic barriers of the NRR at low temperatures in desirable aqueous electrolytes remain a grand challenge due to the inert N≡N bond of the N molecule. Herein, we propose a unique strategy for in situ oxygen vacancy construction to address the significant trade-off between N adsorption and NH desorption by building a hollow shell structured Fe C/Fe O heterojunction coated with carbon frameworks (Fe C/Fe O @C).

Designed Tetranuclear Iron-oxo Clusters with Redox Activity for High-Performance Lithium Storage.

Polyoxometalates (POMs) are considered as promising catalysts with unique redox activity at the molecular level for energy storage. However, eco-friendly iron-oxo clusters with special metal coordination structures have rarely been reported for Li-ion storage. Herein, three novel redox-active tetranuclear iron-oxo clusters have been synthesized using the solvothermal method with different ratios of Fe and SO .

Insights into the multirole CoAl layered double hydroxide on boosting photoelectrochemical activity of hematite: Application to hydrogen peroxide sensing.

As an important compound in many industrial and biological processes, hydrogen peroxide (HO) would cause harmfulness to human health at high concentration level. It thus is urgent to develop highly sensitive and selective sensors for practical HO detection in the fields of water monitoring, food quality control, and so on. In this work, CoAl layered double hydroxide ultrathin nanosheets decorated hematite (CoAl-LDH/α-FeO) photoelectrode was successfully fabricated by a facile hydrothermal process.

On the Robustness of Average Losses for Partial-Label Learning.

Partial-label learning (PLL) utilizes instances with PLs, where a PL includes several candidate labels but only one is the true label (TL). In PLL, identification-based strategy (IBS) purifies each PL on the fly to select the (most likely) TL for training; average-based strategy (ABS) treats all candidate labels equally for training and let trained models be able to predict TL. Although PLL research has focused on IBS for better performance, ABS is also worthy of study since modern IBS behaves like ABS in the beginning of training to prepare for PL purification and TL selection.

A novel photocurable pullulan-based bioink for digital light processing 3D printing.

Digital light processing has significant advantages, such as high repeatability, low failure rate, and no extrusion shear force. To make it possible to print complex structures with high resolution, the consecutive development of photocurable ink materials is indispensable. In this work, photo-functionalized pullulan (Pul-NB) was prepared by introducing norbornene groups into pullulan chains, and an ink material suitable for photocurable printing was prepared by thiol-ene click reaction.

Importance of amylose chain-length distribution in determining starch gelatinization and retrogradation property of wheat flour in the presence of different salts.

Although starch gelatinization and retrogradation properties of wheat flour have been studied with respect to their relations to starch structures, it remains less understood how starch structure and salt (a common food additive) together determine these properties. Gelatinization and retrogradation properties of seven wheat flours with distinct starch structures were thus investigated after adding different salts. NaCl most efficiently increased starch gelatinization temperatures, while KCl showed highest efficiency in retarding the retrogradation degree.

Learning With Proper Partial Labels.

Partial-label learning is a kind of weakly supervised learning with inexact labels, where for each training example, we are given a set of candidate labels instead of only one true label. Recently, various approaches on partial-label learning have been proposed under different generation models of candidate label sets. However, these methods require relatively strong distributional assumptions on the generation models.

N, F Codoped FeOOH Nanosheets with Intercalated Carbonate Anions Rich in Oxygen Defects for Enhanced Alkaline Electrocatalytic Water Splitting.

Alkaline water splitting is a highly efficient and clean technology for hydrogen energy generation. However, in alkaline solutions, most catalysts suffer from extreme instability. Herein, a cross-nanostructured N, F, and CO codoped iron oxyhydroxide composite (N,F-FeO(OH)-CO-NF) rich in oxygen defects is designed for water splitting in the alkaline solution.