The AhR ligand phthiocol and vitamin K analogs as quorum sensing inhibitors.

The aryl hydrocarbon receptor (AhR) protein senses microbial-secreted metabolites to trigger the host's innate immune system. The quinolone signal (PQS) and (MTb) metabolite phthiocol (Pht) are both ligands of AhR with similar chemical structures. As PQS is an essential quorum-sensing molecule that regulates a wide range of virulence factors in , we hypothesized that Pht and its analogs are potential quorum-sensing inhibitors (QSIs) with immune-modulating functions.

Metabolomics analysis and membrane damage measurement reveal the antibacterial mechanism of lipoic acid against .

is a pathogenic microorganism that can cause food-borne diseases. Lipoic acid (LA) has been used as an antioxidant against bacteria, but its antibacterial mechanism is rarely reported. This study aims to explore the antibacterial mechanism of LA and its effect on the metabolites of through membrane damage and metabolomics analysis.

Sex-Specific Differences in the Clinical Profile Among Patients with Tracheobronchial Tuberculosis: A Hospital-Based Cross-Sectional Study in Shenzhen, China.

Purpose: Tracheobronchial tuberculosis (TBTB) has been proposed to occur more commonly in female patients. However, to date, studies that systematically delineate differences between female and male patients with TB infection are lacking. We aimed to comprehensively assess the sex-specific differences in clinical manifestation, bronchoscopy performance, bacteriological examination, and imaging of TBTB in Shenzhen, China.

Evaluation of gallic acid on membrane damage of Yersinia enterocolitica and its application as a food preservative in pork.

This study was aimed to examine the membrane damage mechanism of gallic acid (GA) on Yersinia enterocolitica BNCC 108930, and to explore whether GA can prolong the shelf life of pork. The minimal inhibitory concentration (MIC) of GA against Y. enterocolitica was determined by adopting the broth microdilution method.

Downregulation of CASTOR1 Inhibits Heat-Stress-Induced Apoptosis and Promotes Casein and Lipid Synthesis in Mammary Epithelial Cells.

Heat stress is one of the most important factors limiting the milk yields of dairy animals. This decline can be attributed to the heat-stress-induced apoptosis of mammary epithelial cells (MECs). The cytosolic arginine sensor for mTORC1 subunit 1 (CASTOR1) is a crucial upstream regulator of the mechanistic target of rapamycin complex 1 (mTORC1) signaling, which has close connections with apoptosis.

Processing and characterization of phosphate glass fiber/polylactic acid commingled yarn composites for commercial production.

This study investigated the production of phosphate glass fiber/polylactic acid (PGF/PLA) commingled yarns, textiles and composites for biomedical applications. The PGF volume contents of the composites investigated were 25% and 40%. Plain weave textiles with yarn counts of 10 warp/cm and 6 weft/cm were produced using a commercial weaving machine.

Effects of temperature, oxygen and steam on pore structure characteristics of coconut husk activated carbon powders prepared by one-step rapid pyrolysis activation process.

Activated carbon powders made from coconut husk (CHCs) were prepared by one-step rapid pyrolysis activation process. Effects of temperature, oxygen and steam on the pore structure of CHCs were investigated. Results showed that high temperature, oxygen and steam all motivated the development of the CHCs pore structure.

Effect of CSA concentration on the ammonia sensing properties of CSA-doped PA6/PANI composite nanofibers.

Camphor sulfonic acid (CSA)-doped polyamide 6/polyaniline (PA6/PANI) composite nanofibers were fabricated using in situ polymerization of aniline under different CSA concentrations (0.02, 0.04, 0.

Laccase biosensor based on electrospun copper/carbon composite nanofibers for catechol detection.

The study compared the biosensing properties of laccase biosensors based on carbon nanofibers (CNFs) and copper/carbon composite nanofibers (Cu/CNFs). The two kinds of nanofibers were prepared by electrospinning and carbonization under the same conditions. Scanning electron microscopy (SEM), X-ray diffraction (XRD) and Raman spectroscopy were employed to investigate the morphologies and structures of CNFs and Cu/CNFs.

Design of large-bandwidth single-mode operation waveguides in silicon three-dimensional photonic crystals using two guided modes.

We report on the design of silicon three-dimensional (3D) photonic crystal (PC) waveguides with a combination of acceptor-type and donor-type line defects. Tuning the width of the acceptor-type line defect allows the waveguide to support two guided modes, which enable single-mode propagation over 98.7% of the complete photonic bandgap (cPBG).

Sonochemical synthesis of ordered SnO₂/CMK-3 nanocomposites and their lithium storage properties.

In this study, we successfully prepare SnO(2) nanoparticles inside the pore channels of CMK-3 ordered mesoporous carbon via sonochemical method. The content of SnO(2) is 17 wt % calculated according to the energy-dispersive X-ray spectroscopy (EDS) result. CMK-3 with 17 wt % loading of SnO(2) nanoparticles has a large specific surface area and pore volume.