Simultaneous regulation of grain size and interface of single-crystal ultrahigh-nickel LiNiCoMnO via one-step LiZrO coating.

Single-crystal ultrahigh-nickel LiNiCoMnO (NCM) materials are recognized for significant potential in the development of high-performance lithium-ion batteries, primarily owing to their higher energy density and superior cycling performance compared to polycrystalline counterparts. However, these materials require high calcination temperatures, suffer from significant lithium/nickel mixing, and face challenges in composition control. Although high-activity oxide precursors prepared via spray pyrolysis can reduce calcination temperatures, the smaller particle size of the resulting NCM materials intensifies interfacial side reactions.

Silica Confinement for Stable and Magnetic Co-Cu Alloy Nanoparticles in Nitrogen-Doped Carbon for Enhanced Hydrogen Evolution.

Ammonia borane (AB) with 19.6 wt % H content is widely considered a safe and efficient medium for H storage and release. Co-based nanocatalysts present strong contenders for replacing precious metal-based catalysts in AB hydrolysis due to their high activity and cost-effectiveness.

Modulating Electronic Metal-Support Interactions to Boost Visible-Light-Driven Hydrolysis of Ammonia Borane: Nickel-Platinum Nanoparticles Supported on Phosphorus-Doped Titania.

Ammonia borane (AB) is a promising material for chemical H storage owing to its high H density (up to 19.6 wt %). However, the development of an efficient catalyst for driving H evolution through AB hydrolysis remains challenging.

Indicators of Oxidative Stress in the Prediction of Coronary Artery Lesions in Patients With Kawasaki Disease.

Objectives: The aim of this study was to examine the clinical significance of oxidative stress (OS)-related indices, including inflammatory markers and lipid and platelet (PLT) parameter, in coronary artery lesions (CALs) in Kawasaki disease (KD).

Methods: Clinical data of 952 KD patients diagnosed between January 2019 and March 2022 were collected and divided into CAL and NCAL groups. All the KD patients were randomly divided into training set and verification set.

Effects of laccase and cellulase on saccharification of barley malt.

Improving saccharification of barley malt is beneficial to promoting economic benefits of beer brewers, but there are few detailed reports on the application of cellulase and laccase in barley malt. So, barley malt was pretreated by cellulase and laccase, and the malt wort and brewer's spent grains were analyzed by HPLC, FTIR and SEM in this study. The concentration of malt wort was increased significantly to 8.

Characterization of Modification Patterns, Biological Function, Clinical Implication, and Immune Microenvironment Association of mA Regulators in Pancreatic Cancer.

N-methyladenosine (mA) modification may modulate various biological processes. Nonetheless, clinical implications of mA modification in pancreatic cancer are undefined. Herein, this study comprehensively characterized the mA modification patterns in pancreatic cancer based on mA regulators.

Highly-Dispersed Submicrometer Single-Crystal Nickel-Rich Layered Cathode: Spray Synthesis and Accelerated Lithium-Ion Transport.

For conventional polycrystalline Ni-rich cathode material consisting of numerous primary particles in disordered orientation, the crystal anisotropy in charge/discharge process results in the poor rate capability and rapid capacity degradation. In this work, highly-dispersed submicron single-crystal LiNi Co Al O (SC-NCA) cathode is efficiently prepared by spray pyrolysis (SP) technique followed by a simple solid-state lithiation reaction. Porous Ni Co Al O precursor prepared via SP exhibits high chemical activity for lithiation reaction, enabling the fabrication of single-crystal cathode at a relatively low temperature.

Crustal Density Structure of the Jiuzhaigou Ms7.0 Earthquake Area Revealed by the Barkam-Jiuzhaigou-Wuqi Gravity Profile.

The Barkam-Jiuzhaigou-Wuqi gravity profile extends across the Jiuzhaigou Ms7.0 earthquake (in 2017) zone and passes through several historical big earthquakes' zones. We have obtained Bouguer gravity anomalies along the profile composed of 365 gravity observation stations with Global Positioning System (GPS) coordinates, analyzed the observed data and inverted subsurface density structure.

Urate crystal deposition in hyperuricemic children: a dual energy computed tomography study.

Introduction: The incidence of hyperuricemia (HUA) at younger ages is increasing along the coastal regions of China. This study aimed to compare the frequency of dual energy CT (DECT) urate crystal deposition between symptomatic hyperuricemic children and asymptomatic hyperuricemic children.

Material And Methods: Fifty-six hyperuricemic children were divided into a Joint Group ( = 33) and an Asymptomatic Group ( = 23) according to whether they had a history of arthritis symptoms, which includes rapid onset monoarthritis with intense pain and swelling.

Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.

Lysine succinylation (Ksucc) is an evolutionarily conserved and widespread post-translational modification. Histone acetyltransferase 1 (HAT1) is a type B histone acetyltransferase, regulating the acetylation of both histone and non-histone proteins. However, the role of HAT1 in succinylation modulation remains unclear.

IFN-α confers epigenetic regulation of HBV cccDNA minichromosome by modulating GCN5-mediated succinylation of histone H3K79 to clear HBV cccDNA.

Background: Hepatitis B virus covalently closed circular DNA (HBV cccDNA) is assembled by histones and non-histones into a chromatin-like cccDNA minichromosome in the nucleus. The cellular histone acetyltransferase GCN5, displaying succinyltransferase activity, is recruited onto cccDNA to modulate HBV transcription in cells. Clinically, IFN-α is able to repress cccDNA.

Chronic ethanol consumption and HBV induce abnormal lipid metabolism through HBx/SWELL1/arachidonic acid signaling and activate Tregs in HBV-Tg mice.

Chronic ethanol consumption as a public health problem worldwide boosts the development of chronic liver diseases in hepatitis B virus (HBV)-infected patients. Arachidonic acid metabolite prostaglandin E2 (PGE2) activates regulatory T cells (Tregs) function. Here, we aim to investigate the underlying mechanism by which chronic ethanol consumption enriches the HBV-induced abnormal lipid metabolism and Tregs.

IFN-α2b inhibits the ethanol enriched-HBV cccDNA through blocking a positive feedback loop of HBx/MSL2/cccDNA/HBV/HBx in liver.

Hepatitis B virus (HBV) is a major risk factor for liver diseases, in which HBV covalently closed circular DNA (cccDNA), as the genomic form that templates viral transcription, plays crucial roles in sustaining viral persistence. Clinically, the excessive ethanol intake accelerates the progression of liver diseases with HBV infection. Here, we supposed that ethanol might trigger HBV cccDNA in the liver.

Insight into the preparation of the 2016 M6.4 Menyuan earthquake from terrestrial gravimetry-derived crustal density changes.

Geophysical processes of the pre-earthquake activities are difficult to be determined since less pre-seismic signal is observed directly. Crustal density changes derived from the periodical terrestrial gravimetry may provide meaningful deep information for the pre-earthquake cue. In this study, the crustal density changes following the 2016 M6.

SPIN1 triggers abnormal lipid metabolism and enhances tumor growth in liver cancer.

Abnormal lipid metabolism plays crucial roles in the development of cancer. Spindlin 1 (SPIN1) involving the process of spindle organization and chromosomal stability serves as an important player in the carcinogenesis. In this study, we try to identify the new function of SPIN1 in lipid metabolism of liver cancer.

Effect of glycerol on the physicochemical properties of films based on legume protein concentrates: A comparative study.

The overall goal of this research was to examine the mechanical, water vapor barrier properties and opacity of films prepared using legume protein concentrates (faba bean, pea, lupin, lentil, and soy) as a function of glycerol concentration (50, 75, or 100% [wt/wt]-relative to the protein weight). Overall, tensile strength (TS) decreased with increasing glycerol concentration, whereas tensile elongation (TE) and water vapor permeability (WVP) increased with increasing glycerol concentration. Film opacity was independent of glycerol concentration.

Identification and Characterization of Gastrointestinal-Resistant Angiotensin-Converting Enzyme Inhibitory Peptides from Egg White Proteins.

Egg proteins are recognized as excellent sources of bioactive peptides, such as angiotensin-converting enzyme inhibitory (ACEi) peptides. Oral administration of a thermolysin-digested egg white hydrolysate (T-EWH) caused a significant blood pressure reduction in spontaneously hypertensive rats; a further ACEi assay implied that its ACEi activity was enhanced after in vitro gastrointestinal (GI) digestion. These results indicated that T-EWH contained ACEi peptides resisting GI digestion and/or being further released during GI digestion.

Purification and characterization of antioxidant peptides from cooked eggs using a dynamic in vitro gastrointestinal model in vascular smooth muscle A7r5 cells.

Antioxidant peptides derived from food sources are considered as safer alternatives to commercially available antioxidant drugs. As one of the most abundant protein sources, hen's egg proteins were extensively used to produce antioxidant peptides by enzymatic hydrolysis. Our previous work indicated that gastrointestinal digestion of cooked eggs significantly increased the antioxidant activity due to hydrolysis of egg proteins.

Elevated Interleukin 1β and Interleukin 6 Levels in the Serum of Children With Hyperuricemia.

Purposes: The aim of this study was to investigate the serum levels and clinical significance of interleukin 1β (IL-1β) and IL-6 in children with hyperuricemia (HUA).

Methods: We included 71 children with HUA and 71 children with no HUA as control subjects. Children with HUA were divided into groups I and II according to whether they had a history of acute gout-like attacks (including sudden monoarthritis of rapid onset with intense pain and swelling).

[Values of fat saturation sequence in MRI for juvenile arthritis].

To explore the values of fat saturation sequence in MRI for juvenile arthritis.
 Methods: A total of 1 131 cases with juvenile arthritis and 1 601 with symptomatic arthritis were examined by MRI normal T1 weighted imaging (T1WI) and T2 weighted imaging (T2WI) sequence and spectral presaturation attenuatedinversion recovery (SPAIR) T2 fat saturation sequence. All the images were independently evaluated by two senior doctors from the Department of Radiology and the Department of Pediatric Rheumatology and Immunology respectively to confirm the types and degree of pathological changes of joint tissues.

Elevated urinary monocyte chemoattractant protein-1 levels in children with Henoch-Schonlein purpura nephritis.

Background: Chemokine monocyte chemoattractant protein-1 (MCP-1) has been proved as a potential urinary biomarker in nephropathies. The aim of this study was to investigate the urinary monocyte chemoattractant protein-1 (MCP-1) levels and clinical significance in Henoch-Schonlein purpura (HSP) children with and without nephritis and determine the association of MCP-1 with proteinuria.

Methods: A total of 261 HSP children-with or without nephritis-and 84 healthy control children were enrolled in this study.

Urinary Macrophage Migration Inhibitory Factor as a Noninvasive Biomarker in Pediatric Henoch-Schönlein Purpura Nephritis.

Purposes: The aims of this study were to investigate urinary macrophage migration inhibitory factor (MIF) levels and their clinical significance in Henoch-Schönlein purpura (HSP) children with or without nephritis (N) and to assess the influence of steroid treatment on the urine MIF levels of HSPN patients.

Methods: Group I comprised 35 children with HSPN who were examined twice (A before treatment and B after steroid treatment). Group II comprised 41 children with HSP.

An improved method to extract and purify cystatin from hen egg white.

Hen egg white cystatin, an inhibitor of cysteine proteinase, may have wide applications for improving human health. However, its pricy cost associated with extraction and preparation has hurdled its further utilization. The objective was to develop an improved method to extract and purify cystatin from egg white.

Sensing mechanism for biothiols chemosensor DCO: roles of excited-state hydrogen-bonding and intramolecular charge transfer.

The biothiols sensing mechanism of (E)-7-(diethylamino)-3-(2-nitrovinyl)-2H-chromen-2-one (DCO) has been investigated using the density functional theory (DFT) and time-dependent DFT methods. The theoretical results indicate that the excited-state intermolecular hydrogen bonding (H-B) plays an important role for the biothiols sensing mechanism of the fluorescence sensor DCO. Multiple H-B interaction sites exist in DCO and in its Michael addition product DCOT, which then induce the formation of the H-B complexes with water molecules, DCOH2 and DCOTH4.

Steady-state and time-resolved spectroscopic investigations on the existence of stable methanol/AOT/n-heptane reverse micelles.

In this work, we have reported our study on the controversial issue whether methanol molecules can be effectively encapsulated by surfactant AOT to form true reverse micelles. We compared the different photophysical properties of coumarin 153 (C153) in methanol/AOT/n-heptane reverse micelles and methanol/n-heptane binary mixture by means of steady-state absorption, fluorescence and time-resolved fluorescence spectroscopies. In the reverse micelles, the fluorescence emission spectra of C153 were dependent on the excitation wavelength, while in binary mixtures, the excitation wavelength dependence was not observed.