Publications by authors named "Jiapei Shi"
Successful bone regeneration requires close cooperation between bone marrow mesenchymal stem cells (BMSCs) and macrophages, but the low osteogenic differentiation efficiency of stem cells and the excessive inflammatory response of immune cells hinder the development of bone repair. It is necessary to develop a strategy that simultaneously regulates the osteogenic differentiation of BMSCs and the anti-inflammatory polarization of macrophages for accelerating the bone regeneration. Herein, calcium-chlorogenic acid nanoparticles (Ca-CGA NPs) are synthesized by combining the small molecules of chlorogenic acid (CGA) with Ca.
View Article and Find Full Text PDFObjective: It is imperative to popularize the tertiary prevention of chronic obstructive pulmonary disease (COPD) and to improve the diagnosis and treatment.
Methods: COPD patients were divided into mild ( = 18), moderate ( = 20), severe ( = 24), and extremely severe ( = 22) groups for performing high-resolution computed tomography (HRCT) and pulmonary function test. Serum procalcitonin (PCT) and high-sensitivity C-reactive protein (hs-CRP) were detected, and the occurrence rate of acute exacerbation COPD (AECOPD) was recorded during a 12-months follow-up period.
Article Synopsis
- Glioblastoma is a highly aggressive brain tumor with challenging treatment options due to the blood-brain barrier and high recurrence rates following surgery.
- This study investigates molecular drivers of glioblastoma progression by analyzing gene expression profiles and identifying six key hub genes linked to disease progression.
- The research highlights two upregulated genes with potential clinical significance, evaluates gene expression differences across glioblastoma subtypes, and uses survival analysis to suggest that some identified genes may serve as predictive biomarkers for patient outcomes.