Publications by authors named "Jiapei Liao"
Article Synopsis
- Catharanthus roseus, a plant used in Chinese folk medicine, contains valuable secondary metabolites, but its polysaccharides, which may aid in immunotherapy, have been under-explored.
- Two novel polysaccharides, CRPS-1 and CRPS-2, were isolated and characterized, revealing distinct structures and molecular weights, with CRPS-2 being lighter.
- CRPS-2 notably improved immune cell functions and activated important signaling pathways, indicating its potential for developing health-promoting functional foods.
Aims: Fungi-derived exosome-like nanovesicles (ENs) are emerging as a highly promising class of nanoparticles, particularly noted for their cost-effective production. However, their impact on immune regulation and their potential as anti-tumor agents need further exploration. Our study specifically focused on the investigation of the immunomodulatory and anti-tumor properties of ENs derived from Cordyceps militaris, an edible fungus that had achieved large-scale commercial production, referred to as CMDENs.
View Article and Find Full Text PDFBackground: Plant-derived exosomes-like nanovesicles (PDENs) have been found to be advantageous in disease treatment and drug delivery, but research on their biogenesis, compositional analysis, and key marker proteins is still in its infancy, which limits the standardized production of PDENs. Efficient preparation of PDENs continues to be a major challenge.
Results: Novel PDENs-based chemotherapeutic immune modulators, Catharanthus roseus (L.