Publications by authors named "Jiaomei Zhang"

Background: Potatoes, a major economic crop, are significantly impacted by Fusarium dry rot, a prevalent postharvest disease. Despite the broad-spectrum antimicrobial properties of cinnamaldehyde, a naturally-derived plant substance, its efficacy against the causal pathogen of potato dry rot (Fusarium oxysporum) and the underlying mechanisms have not been extensively studied.

Results: Our study demonstrates that cinnamaldehyde effectively inhibits the growth of Fusarium oxysporum, the pathogen responsible for potato dry rot, and increases its sensitivity to environmental stress factors such as extreme temperatures and high salt stress.

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Article Synopsis
  • Brain tumors, such as gliomas and brain metastases, are challenging to treat due to their ability to block effective drug delivery through the blood-brain barrier (BBB) and blood-brain tumor barrier (BTB).
  • Magnetic nanoparticles (MNPs) are emerging as promising drug delivery vehicles due to their unique properties, allowing enhanced targeting and treatment options like magnetic thermal therapy.
  • Recent research highlights advancements in utilizing MNPs for targeted drug delivery and other therapeutic methods, while also addressing the clinical applications and limitations that hinder their wider use.
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TGA transcription factors (TFs), belonging to the D clade of the basic region leucine zipper (bZIP) family, exhibit a specific ability to recognize and bind to regulatory elements with TGACG as the core recognition sequence, enabling the regulation of target gene expression and participation in various biological regulatory processes. In plant growth and development, TGA TFs influence organ traits and phenotypes, including initial root length and flowering time. They also play a vital role in responding to abiotic stresses like salt, drought, and cadmium exposure.

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Pathogenic oomycetes infect a wide variety of organisms, including plants, animals, and humans, and cause massive economic losses in global agriculture, aquaculture, and human health. Salicylic acid (SA), an endogenous phytohormone, is regarded as an inducer of plant immunity. Here, the potato late blight pathogen was used as a model system to uncover the inhibitory mechanisms of SA on pathogenic oomycetes.

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Background: As a highly prevalent epidemic disease of potato, late blight caused by Phytophthora infestans poses a serious threat to potato yield and quality. At present, chemical fungicides are mainly used to control potato late blight, but long-term overuse of chemical fungicides may lead to environmental pollution and human health threats. Endophytes, natural resources for plant diseases control, can promote plant growth, enhance plant resistance, and secrete antifungal substances.

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, the notorious pathogen of potato late blight, leads to a severe decline in potato yields and even harvest failure. We isolated 201 endophytic isolates from healthy root tissues of potatoes, among which 41 showed strong antagonistic activity against . Further, the tolerance to stress and the potential application against potato late blight of these antagonistic isolates were tested.

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Article Synopsis
  • Potato late blight is a disease that makes potatoes grow poorly and lose value.
  • A natural compound called DATS can help fight this disease by stopping its growth and making potatoes healthier.
  • Researchers found that DATS boosts a specific enzyme in potatoes and affects many genes, showing it may help control potato late blight in an important way.
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Recurrent spontaneous abortion (RSA) is a highly heterogeneous complication of pregnancy with the underlying mechanisms remaining uncharacterized. Dysregulated decidualization is a critical contributor to the phenotypic alterations related to pregnancy complications. To understand the molecular factors underlying RSA, we explored the role of longnoncoding RNAs (lncRNAs) in the decidual microenvironment where the crosstalk at the fetal-maternal interface occurs.

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To analyze the pathogenic bacteria, feature of drug resistance and the efficacy of dexamethasone as the auxiliary medication in pediatric refractory purulent meningitis (PM). The 190 refractory PM child patients were selected for the culture of pathogenic bacteria and analysis of drug resistance. In total, 190 pathogenic bacteria were detected, consisting of gram-positive bacteria (77.

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