Problem-solving ability and future time perspective among the Chinese nursing interns: The mediating role of future work self.

Background: The significance of problem-solving ability has been confirmed in numerous studies worldwide, highlighting its role in enhancing the skills of nursing interns and reducing psychological pressure. However, existing research indicates that the problem-solving ability of nursing interns urgently needs to be further improved. Limited research has been conducted on the problem-solving ability of nursing interns, and the correlations among problem-solving ability, future time perspective, and future work self of Chinese nursing interns are unclear.

Berberine-doped montmorillonite nanosheet for photoenhanced antibacterial therapy and wound healing.

Bacterial infections pose a substantial threat to human health, particularly with the emergence of antibiotic-resistant strains. Therefore, it is essential to develop novel approaches for the efficient treatment of bacterial diseases. This study presents a therapeutic approach involving BBR@MMT nanosheets (NSs), wherein montmorillonite (MMT) was loaded with berberine (BBR) through an ion intercalation reaction to sterilize and promote wound healing.

Innovative behavior and organizational innovation climate among the Chinese clinical first-line nurses during the Omicron pandemic: The mediating roles of self-transcendence.

Background: During the Omicron pandemic, clinical first-line nurses played a crucial role in healthcare. Their innovative behavior enhanced the quality of nursing and served as a vital factor in driving the sustainable development of the nursing discipline and healthcare industry. Many previous studies have confirmed the significance of nurses' innovative behavior worldwide.

Immunisation with the glycolytic enzyme enolase inhibits dissemination of Treponema pallidum in C57BL/6 mice.

Treponema pallidum (T. pallidum), an obligate extracellular bacterium, is the causative agent of sexually transmitted bacterial diseases. In this study, the glycolytic enzyme enolase (Tp Eno) of T.

Corrigendum: Genome-Wide Identification and Expression Profiling of Germin-Like Proteins Reveal Their Role in Regulating Abiotic Stress Response in Potato.

[This corrects the article DOI: 10.3389/fpls.2021.

Genome-Wide Identification and Expression Profiling of Germin-Like Proteins Reveal Their Role in Regulating Abiotic Stress Response in Potato.

Germin and germin-like proteins (GLPs) perform a significant role in plants against biotic and abiotic stress. To understand the role of GLPs in potato, a comprehensive genome-wide analysis was performed in the potato genome. This study identified a total of 70 genes in the potato genome, distributed among 11 chromosomes.

Genome-Wide Identification and Expression Profiling of DUF221 Gene Family Provides New Insights Into Abiotic Stress Responses in Potato.

The domain of the unknown function 221 proteins regulate several processes in plants, including development, growth, hormone transduction mechanism, and abiotic stress response. Therefore, a comprehensive analysis of the potato genome was conducted to identify the deafness-dystonia peptide (DDP) proteins' role in potatoes. In the present study, we performed a genome-wide analysis of the potato domain of the unknown function 221 (DUF221) genes, including phylogenetic inferences, chromosomal locations, gene duplications, gene structures, and expression analysis.

Expression profiling of pathogenesis-related Protein-1 (PR-1) genes from Solanum tuberosum reveals its critical role in phytophthora infestans infection.

Pathogen-related (PR) proteins are an integral part of plants' defense mechanisms against various types of biotic and abiotic stresses. A little is known about the importance of these PR proteins in potato defense mechanisms. In the current study, a total of 22 pathogenesis-related 1 genes were identified in the potato genome.

Intelligent photothermal dendritic cells restart the cancer immunity cycle through enhanced immunogenic cell death.

Dendritic cells (DCs) play a pivotal role in initiating antigen-specific tumor immunity. However, the abnormal function of DCs owing to the immunosuppressive tumor microenvironment (TME) and the insufficient number of tumor infiltrating DCs could promote immune tolerance and tumor immune escape. Thus, there is great potential to employ DCs to induce efficient antitumor immunity.

Small Peptide-Doxorubicin Co-Assembly for Synergistic Cancer Therapy.

Design of elaborated nanomaterials to improve the therapeutic efficacy and mitigate the side effects of chemotherapeutic anticancer drugs, such as Doxorubicin (Dox), is significant for cancer treatment. Here, we describe a co-assembled strategy, where amphiphile short peptides are co-assembled with Doxorubicin to form nanoscale particles for enhanced delivery of Dox. Two kinds of short peptides, Fmoc-FK (FK) and Fmoc-FKK (FKK), are synthesized.

Noninvasive monitoring of intracellular pH change induced by drug stimulation using silica nanoparticle sensors.

We have synthesized and applied a nanoparticle-based pH sensor for noninvasive monitoring of intracellular pH changes induced by drug stimulation. The pH sensor is a two-fluorophore-doped nanoparticle sensor (2DFNS) that contains a pH-sensitive indicator (fluorescein isothiocyanate, FITC) and a reference dye (tris(2,2'-bipyridyl)dichlororuthenium(II) hexahydrate, RuBPY). The nanoparticles have an average diameter of 42 +/- 3 nm and can easily be taken up by cells for noninvasive intracellular pH measurement.

Identification of live liver cancer cells in a mixed cell system using galactose-conjugated fluorescent nanoparticles.

Bio-functioned fluorescent silica nanoparticles have been synthesized for cell labeling and cell differentiation and have shown great promise as novel fluorescent probes. The galactose-conjugated fluorescent nanoparticles (GCFNPs) have been obtained by the conjugation of amino-modified fluorescent silica nanoparticles with lactobionic acid (LA) through EDAC linkage. The GCFNPs retain excellent biological activity and can be used in bioanalysis as an immunofluorescence assay.

An antisense oligonucleotide carrier based on amino silica nanoparticles for antisense inhibition of cancer cells.

Antisense oligonucleotides (anti-ODNs), which are able to interfere with gene expression at the mRNA level, have potential activity in the treatment of viral infections or cancer. However, the application of therapies based on anti-ODNs is hampered by their instability to cellular nuclease and their weak intracellular penetration. Among the many efforts to increase their stability and cellular penetration have been modifications of ODNs and introduction of particulate carriers.

Uptake of silica-coated nanoparticles by HeLa cells.

Nanoparticles have seen wide applications in cellular research and development. One major issue that is unclear is the uptake of nanoparticles by cells. In this study, we have investigated the uptake of silica-coated nanoparticles by HeLa cells, employing rhoadime 6G isothiocyanate (RITC)-doped nanoparticles as a synchronous fluorescent signal indicator.

Influence of anions on the formation and properties of chitosan-DNA nanoparticles.

Chitosan-DNA nanoparticles were prepared by using different anions (such as chloride, sulfate, citrate, and tripolyphosphate) as mediation agents. The research suggested that the formation and morphological characteristics of chitosan-DNA nanoparticles largely depended on concentration, molecular size, charge number, and chemical structure of anions, as well as chitosan/DNA ratio. The observation by atom force microscopy showed that chitosan-DNA nanoparticles mediated by four anions (in their appropriate range of concentration) had a spherical shape, narrow size distribution, and good monodispersivity.