[Different Echinococcus granulosus antigens induced indoleamine 2,3-dioxygenase expression in dendritic cells].

Objective: To observe the expression of indoleamine 2, 3-dioxygenase (IDO) in dendritic cells (DCs) via different Echinococcus granulosus antigens in vitro.

Methods: Bone Marrow DCs generated from bone marrow precursor cells of C57BL/6 mice and cultured in the presence of recombinant mouse GM-CSF (rmGM-CSF). Then, DCs were induced with 15 microg/ml recombinant antigen B (rAgB), 5 mg/ml mouse hydatid fluid (MHF), 1,000 U/ml IFN-gamma (as positive control), and RPMI 1640 complete medium (as negative control), respectively.

[Clinical effect and safety of liposomal-albendazole and tablet-albendazole for the treatment of human cystic echinococcosis].

Objective: To explore and compare the clinical effect and safety of liposomal albendazole (L-ABZ) and tablet-albendazole (T-ABZ) in the treatment of cystic echinococcosis (CE1, CE2, and CE3).

Methods: A total of 269 cases treated with cystic echinococcosis (CE) in Xinjiang Medical University the First Affiliated Hospital from 1998 to 2008 were reviewed. 51 cases were excluded and 218 cases were enrolled in this research by retrospective case-control method.

[Echinococcus granulosus recombinant antigen B induced IDO expression in mouse bone marrow-derived dendritic cells in vitro].

Objective: To observe the expression of indoleamine 2,3-dioxygenase (IDO) in mouse bone marrow-derived dendritic cells (DCs) after adding Echinococcus granulosus recombinant antigen B (rAgB) in vitro.

Methods: CD11c+ DCs generated from bone marrow precursor cells of C57BL/6 mice and cultured in the presence of recombinant mouse GM-CSF (rmGM-CSF). The morphology of DCs was observed by inverted microscope and scanning electronic microscope.