Confused subcutaneous nodules in children: Differential diagnosis of pilomatricoma in children.

Background: Pilomatricoma is a common but easily misdiagnosed tumor in children.

Aims: To differentiate pilomatricoma from other common subcutaneous nodules in children.

Patients/methods: Misdiagnosed subcutaneous nodules in four children were recorded.

[Misdiagnosis of 3 cases lymphoma due to misjudgement of immunohistochemistry].

Objective: To recognize the importance of analyzing the result of immunohistochemical staining correctly.

Method: Review of the three misdiagnosed cases lymphoma and exploring the causes of misdiagnosis through reviewing their clinics, histopathology and immunohistochemistry.

Results: Case 1 of lymphocyte rich classical Hodgkin's lymphoma (LRCHL) was misdiagnosed as follicular lymphoma (FL) initially, the RS cells were overlooked morphologically and wrongly determined BCL-2 and CD20-positive cells as tumor cells immunohistochemically; also once misdiagnosed as nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) because the CD20-negative RS misjudged cells as the positives.

[Clinical features of 16 cases of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia].

In order to investigate the clinical manifestations, diagnosis, therapy and prognosis of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM), 16 patients with LPL/WM were analyzed retrospectively. The results showed that the average age of 16 patients with LPL/WM was 65.1 years old, the most common syndromes were anemia and hyperviscosity syndrome, bone marrows were composed of small lymphocyte, admixed with variable numbers of plasma cells and plasmacytoid lymphocytes.