Publications by authors named "Jiao-Jiao Hui"
Front Aging Neurosci
April 2023
Article Synopsis
- This study investigates how the effectiveness and safety of selegiline, a drug used for Parkinson's disease (PD), varies over time with different treatment durations.*
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- Researchers analyzed data from multiple databases, included 27 randomized controlled trials (RCTs) and 11 observational studies, and found that longer treatment with selegiline resulted in greater reductions in PD symptoms as measured by various rating scales.*
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- While selegiline was more effective than a placebo, it also posed a higher risk of adverse events, particularly neuropsychiatric disorders, indicating a trade-off between its efficacy and safety profile.*
