Applicability of wheat brewer's spent grain in steamed bread-making based on physicochemical and visual profiles assessment of doughs and breads.

Brewer's spent grain (BSG), one of the main byproducts of brewing, has been widely used in the food industry due to its high nutritional components of dietary fiber, proteins, polysaccharides, and polyphenols. This study investigated the influence of wheat brewer's spent grain (WBSG) on the physicochemical properties of dough and steamed bread-making performance. The incorporation of WBSG in wheat flour significantly increased water absorption, development time, and degree of softening while decreasing the stability time of blending dough.

Innovative Clinical Scenario Simulator for Step-by-Step Microsurgical Training.

Background:  Microsurgical training should be implemented with consideration of operative difficulties that occur in actual clinical situations. We evaluated the effectiveness of a novel clinical scenario simulator for step-by-step microsurgical training that progressed from conventional training to escalated training with additional obstacles.

Methods:  A training device was designed according to multiple and intricate clinical microsurgery scenarios.

Interfacial construction of SnS/ZnCdS nanopolyhedron heterojunctions for enhanced photocatalytic hydrogen evolution.

ZnCdS, a metal chalcogenide solid solution, has attracted significant attention. However, two primary challenges hinder its widespread application in photocatalytic hydrogen evolution: the rapid recombination rate of photogenerated carriers and susceptibility to photo-oxidation in the aqueous environments. In this article, a facile hydrothermal route was employed for the first time to uniformly assemble SnS nanoparticles onto the surface of ZnCdS (ZCS) nanopolyhedra.

Effects of graphene oxide nanosheets on the ultrastructure and biophysical properties of the pulmonary surfactant film.

Graphene oxide (GO) is the most common derivative of graphene and has been used in a large range of biomedical applications. Despite considerable progress in understanding its cytotoxicity, its potential inhalation toxicity is still largely unknown. As the pulmonary surfactant (PS) film is the first line of host defense, interaction with the PS film determines the fate of the inhaled nanomaterials and their potential toxicity.

Physicochemical properties of nanoparticles regulate translocation across pulmonary surfactant monolayer and formation of lipoprotein corona.

Interaction with the pulmonary surfactant film, being the first line of host defense, represents the initial bio-nano interaction in the lungs. Such interaction determines the fate of the inhaled nanoparticles and their potential therapeutic or toxicological effect. Despite considerable progress in optimizing physicochemical properties of nanoparticles for improved delivery and targeting, the mechanisms by which inhaled nanoparticles interact with the pulmonary surfactant film are still largely unknown.