Effect of Moxibustion Combined With Cisplatin on Tumor Microenvironment Hypoxia and Vascular Normalization in Lewis Lung Cancer Mice.

Purpose: This study was developed to evaluate the effects of moxibustion on tumor microenvironmental hypoxia in a murine model of Lewis lung carcinoma (LLC).

Methods: Twenty-four tumor-bearing mice were randomized into tumor group (T), tumor + cisplatin group (TC), tumor + moxibustion group (TM), and tumor + cisplatin + moxibustion group (TMC) (n = 6/group). Six age-matched C57BL/6 mice were employed as control group (Ctrl).

Lateral hypothalamic orexin neurons mediate electroacupuncture-induced anxiolytic effects in a rat model of post-traumatic stress disorder.

The lateral hypothalamus' orexinergic system has been associated with anxiety-related behaviors, and electroacupuncture (EA) modifies orexin neurons to control the anti-anxiety process. However, in a rat model of post-traumatic stress disorder (PTSD), the important role of LH orexin neurons (OXNs) in the anxiolytic effects induced by EA has not been explored. In this study, rats underwent modified single prolonged stress (MSPS) for seven days before developing EA.

[Non-linear characteristic of acupoint resistance and its application].

Acupoint specificity is a key scientific issue in acupuncture and moxibustion. Acupoint electric resistance is a commonly-used biophysical index to study the functional specificity of acupoints. The non-linear characteristics of acupoint electric resistance have great impacts on the measured values, but it has been greatly ignored.

The characteristics of registered acupuncture clinical trials enrolling cancer patients.

Purpose: This study sought to explore and summarize the global state of acupuncture clinical trials enrolling cancer patients included in international registries to date.

Methods: All relevant trials evaluating acupuncture-related interventions for the treatment of cancer that were registered in 16 trial registries from January 1, 2001, through December 31, 2020, were identified. Subsequent publications related to these trials were additionally retrieved from the PubMed, Cochrane Library, Embase, CNKI (China National Knowledge Infrastructure), VIP (China Science and Technology Journal Database), and Wanfang databases.

Exploring the perceptions of the educational environment in online acupuncture learning during the COVID-19 pandemic.

Objective: Students have had to adapt to a "new normal" of online education at home during the COVID-19 pandemic. This poses a considerable challenge to the conduct of online acupuncture courses. Here, we provide our experience and guidance for conducting an online experimental acupuncture course during the COVID-19 pandemic.

Laser Moxibustion Alleviates Knee Osteoarthritis Pain by Inhibiting Spinal Microglial Activation-Mediated Neuroinflammation in Rats.

Central sensitization driven by glial activation-mediated neuroinflammation is recognized as a key mechanism in pain processing. Laser moxibustion using low-intensity laser irradiation of corresponding acupoints significantly relieves knee osteoarthritis (KOA) pain. However, the underlying mechanism of its effects on KOA pain is still not completely understood.

The Effects of Laser Moxibustion on Knee Osteoarthritis Pain in Rats.

Although chronic pain affects the quality of life of patients with osteoarthritis, current medical treatments are either ineffective or have long-term side effects. Recently, low-intensity laser irradiation of corresponding acupoints was demonstrated to alleviate pain. The aim of the present study was to investigate the effects of 10.

Research on the Characteristics of Infrared Radiation Spectra at Zigong Acupoint within Menstrual Cycle of Healthy Female.

The purpose of this study was to observe the characteristics of infrared radiation spectrum of Zigong acupoint (EX-CA1) within the menstrual cycle of healthy female. We used highly sensitive infrared radiation spectrum detection system and phase-locked amplification technology to detect and analyse the infrared radiation spectrum from 1.5m to 18m of 32 healthy female before, during, and after menstruation at EX-CA1 and control points.

Effects of infrared laser moxibustion on cancer-related fatigue in breast cancer survivors: Study protocol for a randomized controlled trial.

Background: Cancer-related fatigue (CRF) is the most common and distressing symptom associated with cancer treatment that breast cancer survivors (BCS) experience. We previously found that laser moxibustion may be efficacious for CRF. The primary aim of this study is to determine the specific efficacy of 10.

Besides Photothermal Effects, Low-Level CO Laser Irradiation Can Potentiate Skin Microcirculation Through Photobiomodulation Mechanisms.

Improvement of microcirculation is one of the important mechanisms of low-level laser therapy (LLLT) to treat some diseases such as wound healing. Most previous studies have been carried out with multiple lasers other than the 10,600-nm CO laser. Recently, the CO laser has been used not only as a tool for excision of soft tissues but also for therapeutic applications.

Examination of the cellular mechanisms of leukocyte elevation by 10.6 μm and 650 nm laser acupuncture-moxibustion.

To investigate the cell cycle and cellular mechanisms of leukocyte elevation by laser acupuncture in rats with cyclophosphamide (CTX)-induced leukopenia. Sixty-six rats were randomized into six groups: normal, model control group, sham treatment group, 10.6 μm laser treatment group, 650 nm laser treatment group, and 10.

Effects of infrared laser moxibustion on cancer-related fatigue: A randomized, double-blind, placebo-controlled trial.

Background: Fatigue is the most common symptom negatively affecting the quality of life of patients with cancer. The objective of the current study was to evaluate the preliminary efficacy and safety of 10.6-μm infrared laser moxibustion for cancer-related fatigue (CRF).

Heat induces adenosine triphosphate release from mast cells in vitro: a putative mechanism for moxibustion.

Objective: To investigate the role of adenosine tri-phosphate (ATP) purinergic signaling in mast cells (MCs) modulated by heat to further understand the molecular mechanisms of moxibustion.

Methods: Skin temperatures induced by monkshood cake moxibustion were evaluated by measuring the Neiguan acupoint (PC 6) from 31 participants with a digital thermocouple thermometer. Temperatures of 43 °C and 52 °C were applied to cultured human leukemia mast cell line HMC-1 in vitro.

Research on nonlinear feature of electrical resistance of acupuncture points.

A highly sensitive volt-ampere characteristics detecting system was applied to measure the volt-ampere curves of nine acupuncture points, LU9, HT7, LI4, PC6, ST36, SP6, KI3, LR3, and SP3, and corresponding nonacupuncture points bilaterally from 42 healthy volunteers. Electric currents intensity was increased from 0 μA to 20 μA and then returned to 0 μA again. The results showed that the volt-ampere curves of acupuncture points had nonlinear property and magnetic hysteresis-like feature.

The effect of electroacupuncture on extinction responding of heroin-seeking behavior and FosB expression in the nucleus accumbens core.

Augmentation of extinction with learning enhancing therapy may offer an effective strategy to combat heroin relapse. Our lab previously found that electroacupuncture (EA) not only significantly reduced cue-induced reinstatement of heroin seeking but also exhibited a promoting effect on the ability of learning and memory. In the present study, we further investigated the effects of EA on the extinction of heroin-seeking behavior in rats with a history of intravenous heroin self-administration.

The infrared radiation spectrum of acupoint taiyuan (LU 9) in asthma patients.

Objective: To analyze the distinctive pathological characteristics in the spectrums of spontaneous infrared radiation at the Taiyuan (LU 9) acupoint in patients with asthma.

Methods: A highly sensitive infrared spectrum detecting device was used to detect the spectrums of spontaneous infrared radiation at Taiyuan (LU 9) in 37 asthma patients and 34 healthy volunteers.

Results: Asthma patients had significantly lower infrared intensity than that of the healthy volunteers (P>0.

Infrared radiation spectrum of acupuncture point on patients with coronary heart disease.

The objective of this study was to compare the acupoint infrared radiation spectrums of patients and healthy volunteers to show whether those of coronary heart disease (CHD) patients carry distinctive pathological information. PHE201, using a highly sensitive infrared spectrum detection device applied to the acupoint Neiguan (PC6) and to a control point on 50 CHD patients and 47 healthy adults. A total of 73 wavelength spots were detected.

[Investigation of pathway and mechanism of heat stimulating action of sandwiched moxibustion].

Based on the literature review and theories of biophysical theory, the pathway and mechanism of the heat of sandwiched moxibustion stimulating acupoints are analyzed. It is concluded that the heat of sandwiched moxibustion is transferred to the skin of acupoints by heat conduction and thermal radiation. The heat conduct from the skin to deep tissues and other parts was carried out through the biological heat conduction systems.

[Effect of infrared laser on pituitrin-induced bradycardia in rabbits].

Objective: To observe the effect of infrared laser stimulation on Neiguan (PC 6) for bradycardia of rabbits induced by injection of pituitrin.

Methods: 10.6 microm CO(2) infrared laser, 650 nm semiconductor red laser and the compound laser of their aggregation were sent out by a compound laser sanatory instrument to stimulate Neiguan (PC 6) respectively for the purpose of analyzing the differences of the effects exerted by infrared laser and red laser as well as the changes of the effects after their aggregation.

An infrared radiation study of the biophysical characteristics of traditional moxibustion.

Objectives: Moxibustion has been a part of acupuncture practice for thousands of years. Traditionally, it includes direct moxibustion, in which moxa sticks are burned at acupuncture points on the skin, and indirect moxibustion, in which monkshood cakes or ginger or garlic slices are used to insulate the skin from burning moxa cones. Recently randomised clinical trials and clinical observations suggest that moxibustion can enhance physiological and immune functions, but there has been little investigation of the scientific basis of these traditional techniques.

[The resistance of acupoint and its measurement].

We have analysed the significance of acupoint resistance and some probable problems in its measurement according to biophysics theories and we believe that the skin resistance plays an important role in acupoint resistance. The Volt-ampere curve should be used to describe acupoint resistance, and only when the measurements are under the same condition should the results be compared, because acupoint resistance is nonlinear. The acupoint resistance could be detected only in vivo.

[Observation on the characters of infrared radiation spectrum of acupoints in normal humans and CHD patients].

In this experiment the data of the infrared radiation spectrum of acupoints in human body were obtained through an ingenious device. In thirty-one healthy volunteer subjects and thirty-one patients suffering from coronary heart disease, we detected the infrared radiation spectra from some acupoints and compared them with those of the healthy subjects. The curves of patients showed more differences.

[Volt-ampere characteristics of Yuan points of three yin channels of hand in women before, during and after menstruation].

Objective: To observe the changes of volt-ampere characteristics of Yuan-Primary acupoints in women before, during and after menstruation, and to find out the relationships between Qi-blood in human body and volt-ampere characteristics of acupoints, so as to develop a new method for quantitative analysis on changes of Qi-blood.

Methods: A high-sensitive detection system of volt-ampere characteristics of acupoint was applied to detecting the volt-ampere characteristics of Taiyuan (LU 9), Daling (PC 7) and Shenmen (HT 7) in healthy women before, during and after menstruation.

Results: The resistances on LU 9, PC 7 and HT 7 with some certain scan currents were quite different among the women before, during and after menstruation.

Effect of different LLLT on pituitrin-induced bradycardia in the rabbit.

The objective of this paper was to observe the effect of low-level combined- or single-laser irradiation on bradycardia produced by pituitrin in rabbits. A combined-laser apparatus was made. A 10.