Anti-HBc mirrors the activation of HBV-specific CD8 T cell immune response and exhibits a direct effect on HBV control.

Background: Hepatitis B core antibody (anti-HBc) is commonly present in patients with chronic hepatitis B virus (HBV) infection and serves as a marker of humoral immunity. Herein, we aim to investigate the correlation between anti-HBc and antiviral immune response and its putative role in HBV control.

Methods: Quantitative anti-HBc and levels of anti-HBc subtypes were measured in chronic hepatitis B (CHB) patients.

Assessment of severity of leukoaraiosis: a diffusional kurtosis imaging study.

Objective: The objective was to investigate the capabilities of diffusional kurtosis imaging (DKI) in detection of age-related white matter (WM) changes in elderly patients with leukoaraiosis.

Material And Methods: Fractional anisotropy (FA), kurtosis, and diffusion parameters in the frontal lobe and parietal lobe were compared between 14 patients at Fazekas scale 0 and 1, and 15 patients at Fazekas scale 2 and 3.

Results: FA and DKI parameters were significantly altered in the ischemic lesions vs normal regions of WM in the severe patients.