Publications by authors named "Jianzhang Feng"

Background: Awareness of hypertension, as well as its prevalence, treatment, and control status, has not been comprehensively investigated in Macau Special Administrative Region (SAR), China.

Methods: A survey was conducted on a randomly sampled population of 1,410 participants (n = 638 men) aged 18-93 years in 2012. Blood pressure was individually measured twice.

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Chinese populations are known to be at risk for vitamin D deficiency, with some evidence that this is due to lack of exposure to sunlight. Vitamin D deficiency and/or low sun exposure have been associated with higher incidence of hypertension in Caucasians. Thus, we investigated these associations in a Chinese population with a high rate of hypertension.

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Background: The evaluation of patients with acute chest pain is time consuming and complicated. In the present study, the role of the bedside troponin T (TnT) test was prospectively investigated for predicting the risk of death and acute heart failure (AHF) in patients with acute chest pain.

Methods: Five hundred two consecutive patients admitted in the 24 h after the onset of chest pain were enrolled in the study.

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Objective: To investigate the effects of C-type natriuretic peptide (CNP) gene transduction on neointimal hyperplasia and endothelial function after angioplasty.

Methods: Eighty-four rabbits were divided into 3 equal groups, namely normal control group, alkaline phosphatase gene transduction group and CNP gene transduction group. The rabbits in the latter two groups were given high-cholesterol diet 7 d before the experiment, followed by establishment of restenosis models by injuring the iliac artery and the specified gene transfer via retroviral vectors.

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Objective: To induce the differentiation of rabbit bone marrow mesenchymal stem cells (MSCs) into myogenic cells in vitro, and to investigate the expression of vascular endothelial growth factor (VEGF) gene in AdTrackCMV-hVEGF165- transfected MSCs.

Methods: Twenty rabbits were divided equally into control group and experimental group, and MSCs were isolated and purified from their bone marrow by Percoll (1.073 g/ml) followed by cell culture in low-glucose DMEM supplemented with 10% fetal bovine serum.

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Article Synopsis
  • The study aimed to evaluate how transferring phVEGF165 affects vascular remodeling following balloon injuries in rabbits.
  • Ninety rabbits were divided into three groups and monitored for changes in artery structure after receiving a hypercholesterol diet and different treatments over various time intervals.
  • Results showed that group receiving phVEGF165 had significantly smaller neointimal areas and better lumen conditions compared to the other groups, suggesting that this gene transfer positively influences vascular healing and could help prevent restenosis.
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We evaluated the effect of basic fibroblast growth factor (bFGF) on the extent of atherosclerosis and balloon injury-induced vasoproliferation in atherosclerotic animals with acute myocardial infarction (AMI). Fifty-six rabbits were fed a 1% cholesterol diet. Balloon injury of iliac arteries and experimental acute myocardial infarction were induced in the same animals.

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