Publications by authors named "Jianyou Zhu"

In order to develop uniform diagnostic standards and reporting terminology, the International Academy of Cytology and the American Society of Cytopathology have recommended the establishment of the International System for Reporting Serous Fluid Cytopathology (ISRSFC). ISRSFC has 5 diagnostic categories: non-diagnostic (ND), negative for malignancy (NFM), atypia of unknown significance (AUS), suspicious for malignancy (SFM), and malignant (MAL). So far, very few studies have evaluated the risk of malignancy (ROM) and performance characteristics (sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy) of different categories.

View Article and Find Full Text PDF
Article Synopsis
  • MiR-27 shows significant expression in heart development and its role in myocarditis is unclear, prompting a study to explore its biological characteristics in injured heart cells (H9c2).
  • The research involved treating H9c2 cells with LPS to induce damage, and then manipulating miR-27 levels to assess effects on cell viability and apoptosis, while evaluating its interaction with ICAM1 through various assays.
  • Results indicated that low miR-27 levels due to LPS treatment increased cell death, whereas restoring miR-27 enhanced cell survival and reduced apoptosis, suggesting miR-27 protects against injury by modulating ICAM1 and NF-κB pathway activities.
View Article and Find Full Text PDF

Recent data indicate that the tight junction proteins are abnormally regulated in several human cancers and the expression of these proteins is involved in the etiology and progression of cancer. To explore the expression distinction of the tight junction proteins claudin-5, -7, -8 and -9 in the adjacent non-neoplastic tissues and cervical carcinoma tissues, 72 cervical carcinoma tissues and the samples of non-neoplastic tissues adjacent to the tumors were examined for expression of claudin-5, -7, -8 and -9 by streptavidin-perosidase immunohistochemical staining method. The positive expression rates of claudin-5 in cervical carcinoma tissues and adjacent non-neoplastic tissues were 31.

View Article and Find Full Text PDF

The aim of this study was to assess the effect of infection and drug therapy on functional dyspepsia (FD) symptoms and gastrointestinal eosinophil count. In this study, 215 continuous FD patients fulfilling Rome III criteria were enrolled. The patients were divided into a -positive group and a -negative group.

View Article and Find Full Text PDF