Publications by authors named "Jianyong Yan"

Bracts are the metamorphic non-flower organ in angiosperm plants. The variation of the color and shape of bracts was found to be neo-functionalized (i.e.

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. Thiopental is an anesthetic drug related to the condition of controlling the area of neurological contexts. This study is related to the analysis of effectiveness for the condition of thiopental application on spontaneously hypertensive rats.

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Background: Propofol acts as an intravenous anesthetic cure which is widely used as a therapy for the craniocerebral injury that comprised surgical anesthesia as well as the sedation done in the intensive care units. Propofol is one of the most commonly used and efficient anesthetics where the painful effects are followed by an injection of propofol. In many cases, patients experience pain followed by anxiety, boredom, fear, and even myocardial ischemia.

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Article Synopsis
  • Osteosarcoma is a prevalent bone cancer primarily affecting children and adolescents, and this study examines how gas anesthetics impact the behavior of osteosarcoma cells, particularly focusing on invasion, metastasis, and response to chemotherapy.
  • Isoflurane and sevoflurane significantly inhibit osteosarcoma cell migration and proliferation at clinically relevant doses, while desflurane is less effective; all anesthetics enhance the effects of chemotherapeutic drugs.
  • The research concludes that gas anesthetics influence the survival, movement, growth, and sensitivity to chemotherapy in osteosarcoma cells, potentially by affecting specific cellular pathways like PI3K/AKT and IGF-1.
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Dexmedetomidine (Dex) possesses analgesic and anaesthetic values and reported being used in cerebral ischaemic injury therapeutics. Accumulating studies have determined the effect of microRNAs (miRNAs) on the cerebral ischaemic injury. Thus, the present study aimed to unravel the molecular mechanism of miR-381 and Dex in cerebral ischaemic injury.

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Hypoxic-ischemic brain damage (HIBD) is a common neurological disorder. Emerging reports reveal that long non-coding RNAs and microRNAs (miRs) are implicated in the progress of HIBD. In this study we tried to ascertain whether lncRNA MALAT1, with the involvement of miR-429 and WNT1, affects HIBD.

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