Regulating the Electronic Band Structure of the Ti-Based Metal-Organic Framework toward Boosting Light-Driven Hydrogen Evolution.

The photocatalytic H evolution rate on the isomorphic nanosheet-based Ti metal organic-frameworks (MOFs) is regulated through changing the length of aromatic carboxylate ligands. For the series of Ti-MOFs, when increasing the length of organic linkers, the band gaps between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) narrow based on density functional theory (DFT) calculation, accompanied by a degree of increase of organic ligand involvement in the LUMO. When increasing the linker length, both the intensities of photoluminescence (PL) and electron paramagnetic resonance (EPR) signals related to Ti gradually decrease, which are opposite to their photocatalytic performance, where the longer the linkers, the higher the hydrogen evolution rate.

Synergistic Modulation of Electronic Interaction to Enhance Intrinsic Activity and Conductivity of Fe-Co-Ni Hydroxide Nanotube for Highly Efficient Oxygen Evolution Electrocatalyst.

The large-scale hydrogen production and application through electrocatalytic water splitting depends crucially on the development of highly efficient, cost-effective electrocatalysts for oxygen evolution reaction (OER), which, however, remains challenging. Here, a new electrocatalyst of trimetallic Fe-Co-Ni hydroxide (denoted as FeCoNiO H ) with a nanotubular structure is developed through an enhanced Kirkendall process under applied potential. The FeCoNiO H features synergistic electronic interaction between Fe, Co, and Ni, which not only notably increases the intrinsic OER activity of FeCoNiO H by facilitating the formation of *OOH intermediate, but also substantially improves the intrinsic conductivity of FeCoNiO H to facilitate charge transfer and activate catalytic sites through electrocatalyst by promoting the formation of abundant Co .

Manipulating the Reaction Pathway of CO Photoreduction via the Microenvironment of a Re Molecular Catalyst.

Re molecular complexes incorporated into two metal-organic frameworks were investigated to disclose the host-guest interaction by infrared and H nuclear magnetic resonance and to explore the microenvironment around the Re complex by absorption and photoluminescence spectra. ZIF-8 provides a confined space to isolated Re via an electrostatic interaction, while UiO-66 exerts a relaxed space to accessible Re via a coordination interaction. For CO two-electron photoreduction to CO, the turnover number of 28.

Co-Fe-P Nanosheet Arrays as a Highly Synergistic and Efficient Electrocatalyst for Oxygen Evolution Reaction.

The rational design and synthesis of highly efficient electrocatalysts for oxygen evolution reaction (OER) is of critical importance to the large-scale production of hydrogen by water electrolysis. Here, we develop a bimetallic, synergistic, and highly efficient Co-Fe-P electrocatalyst for OER, by selecting a two-dimensional metal-organic framework (MOF) of Co-ZIF-L as the precursor. The Co-Fe-P electrocatalyst features pronounced synergistic effects induced by notable electron transfer from Co to Fe, and a large electrochemical active surface area achieved by organizing the synergistic Co-Fe-P into hierarchical nanosheet arrays with disordered grain boundaries.

Revisiting the Environment Effect on Mass Transfer for Heterogenized Pd Ru Metal-Organic Cage Photocatalyst Confined within 3D Matrix.

Artificial light-driven splitting of water into hydrogen involves multiple links to emulate natural photosynthesis, including light absorption, electron or energy transfer, surface catalysis et al., in which, the mass transportation of sacrificial reagent and reactant is always ignored. Metal-organic cage (MOC) of Pd Ru (MOC-16), assembling multiple photosensitive Ru and catalytic Pd concomitant with directional electron transfer between them, provides an opportunity to explore the environmental effects from the view point of mass transportation without disturbance of other links.

Medication reconciliation role and value in Alzheimer's disease treatment.

Background: With the continuous increase of Alzheimer's disease (AD), it is also imminent to treat patients with AD for medication reconciliation.

Objective: To explore the role and value of medication reconciliation in AD treatment.

Methods: 100 patients over 65 years of age diagnosed with AD were randomly separated into two groups: conventional treatment and medication reforming.

Charge State of Au(SG) Nanoclusters Induced by Interaction with a Metal Organic Framework Support and Its Effect on Catalytic Performance.

We investigated the charge transfer between Au(SG) nanoclusters and metal-organic framework (MOF) supports including Mil-101-Cr, Mil-125-Ti, and ZIF-8 by an X-ray photoemission technique and discussed the influence of resulted charge states of supported Au(SG) nanoclusters on the 4-nitrophenol reduction reaction. Charge transfer from Au(SG) to Mil-101-Cr induces positive charge Au (0 < δ < 1) while charge transfer from ZIF-8 to Au(SG) generates negative charge Au due to different metal-support interactions. Au(SG) on Mil-125 shows metallic Au, similar to unsupported Au(SG), due to negligible charge transfer.

Correction: Efficient photocatalytic hydrogen evolution over hydrogenated ZnO nanorod arrays.

Correction for 'Efficient photocatalytic hydrogen evolution over hydrogenated ZnO nanorod arrays' by Xihong Lu et al., Chem. Commun.

A robust photocatalyst of Au@ZIF-8@TiO-ReP with dual photoreductive sites to promote photoelectron utilization in HO splitting to H and CO reduction to CO.

Sustaining long-term chemical or photochemical stability of a homogeneous molecular catalyst remains a significant challenge. We report a remarkable improvement of the activity and stability of a Au25@ZIF-8@TiO2-ReP catalyst via composition engineering with double redox active sites of Au25 NCs and a Re(i) complex for H2 and CO evolution to promote electron utilization.

Heterogenization of Photochemical Molecular Devices: Embedding a Metal-Organic Cage into a ZIF-8-Derived Matrix To Promote Proton and Electron Transfer.

Application of a molecular catalyst in artificial photosynthesis is confronted with challenges such as rapid deactivation due to photodegradation or detrimental aggregation in harsh conditions. In this work, a metal-organic cage [Pd(RuL)] (MOC-16), characteristic of a photochemical molecular device (PMD) concurrently integrating eight Ru light-harvesting centers and six Pd catalytic centers for efficient homogeneous H production, is successfully heterogenized through incorporation into a metal-organic framework (MOF) of ZIF-8 and then transformed into a carbonate matrix of Zn(MeIm)(CO) (CZIF), leading to hybridized MOC-16@CZIF. This MOC@MOF integrated photocatalyst inherits a highly efficient and directional electron transfer in the picosecond domain of MOC-16 and possesses one order increased microsecond magnitude of the triplet excited-state electron in comparison to that of the primitive MOC-16.

Protective Effects of Reduced Beta 2 Glycoprotein I on Liver Injury in Streptozotocin (STZ)-Diabetic Rats by Activation of AMP-Activated Protein Kinase.

BACKGROUND Protective effects of reduced beta 2 glycoprotein I (Rb2GPI) against vascular injury of diabetes mellitus have been extensively investigated. However, the effects of Rb2GPI on liver injury in diabetic animals have not been reported. MATERIAL AND METHODS A diabetic rat model of was produced by systemic injection of streptozotocin (STZ).

Fabrication of Au (SG) -ZIF-8 Nanocomposites: A Facile Strategy to Position Au (SG) Nanoclusters Inside and Outside ZIF-8.

Multifunctional composite materials are currently highly desired for sustainable energy applications. A general strategy to integrate atomically precise Au (SG) with ZIF-8 (Zn(MeIm) , MeIm = 2-methylimidazole), is developed via the typical Zn-carboxylate type of linkage. Au (SG) are uniformly encapsulated into a ZIF-8 framework (Au (SG) @ZIF-8) by coordination-assisted self-assembly.

Association of Thyroid-Stimulating Hormone Levels with Microvascular Complications in Type 2 Diabetes Patients.

BACKGROUND Subclinical hypothyroidism (SCH) is typically featured by elevated serum concentration of thyroid-stimulating hormone (TSH). This study aimed to determine the relationship between TSH levels and microvascular complications in type 2 diabetes patients. MATERIAL AND METHODS A total of 860 type 2 diabetes patients were enrolled in this cross-sectional study.

Serum adipocyte fatty acid-binding protein levels are associated with peripheral arterial disease in women, but not men, with type 2 diabetes mellitus.

Background: Adipocyte fatty acid-binding protein (A-FABP) has been recognized as an important player in macrophage cholesterol trafficking and inflammation, and may promote the development of atherosclerosis. To further elucidate the role of A-FABP in atherosclerosis in diabetes, we investigated the relationship between serum A-FABP concentrations and peripheral arterial disease (PAD) in patients with type 2 diabetes mellitus (T2DM).

Methods: In all, 488 inpatients with T2DM were enrolled in the study (254 men, 234 women; mean (±SD) age 57.

A metal-organic cage incorporating multiple light harvesting and catalytic centres for photochemical hydrogen production.

Photocatalytic water splitting is a natural but challenging chemical way of harnessing renewable solar power to generate clean hydrogen energy. Here we report a potential hydrogen-evolving photochemical molecular device based on a self-assembled ruthenium-palladium heterometallic coordination cage, incorporating multiple photo- and catalytic metal centres. The photophysical properties are investigated by absorption/emission spectroscopy, electrochemical measurements and preliminary DFT calculations and the stepwise electron transfer processes from ruthenium-photocentres to catalytic palladium-centres is probed by ultrafast transient absorption spectroscopy.

Completely <001> oriented anatase TiO2 nanoarrays: topotactic growth and orientation-related efficient photocatalysis.

A TiO2 film has been facilely grown on a Ti foil via a general and simple acid vapor oxidation (AVO) strategy. Based on detailed characterization by using X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM), we found that the TiO2 film was composed of anatase nanoarrays highly oriented along their <001> direction, resulting in a large exposed {001} top surface on the film. The growth mechanism based on a topotactic transformation was proposed according to a careful study of time-dependent experimental results.

Genome-wide association study identifies variants in PMS1 associated with serum ferritin in a Chinese population.

Only a small proportion of genetic variation in serum ferritin has been explained by variant genetic studies, and genome-wide association study (GWAS) for serum ferritin has not been investigated widely in Chinese population. We aimed at exploring the novel genetic susceptibility to serum ferritin, and performed this two stage GWAS in a healthy Chinese population of 3,495 men aged 20-69 y, including 1,999 unrelated subjects in the first stage and 1,496 independent individuals in the second stage. Serum ferritin was measured with electrochemiluminescence immunoassay, and DNA samples were collected for genotyping.

Duration of exercise as a key determinant of improvement in insulin sensitivity in type 2 diabetes patients.

Exercise duration and intensity are important parameters in exercise prescription and play a major role in improving insulin sensitivity (including transient and persistent improvement effects following cessation of training) in patients with type 2 diabetes mellitus (T2DM). However, whether duration or intensity of exercise is the more important factor has yet to be established. Therefore, we aimed to determine whether exercise prescriptions differing in duration and intensity differ in their ability to aid T2DM patients to retain insulin sensitivity following the conclusion of a period of training.

Efficient photocatalytic hydrogen evolution over hydrogenated ZnO nanorod arrays.

Hydrogenated ZnO nanorod arrays (NRAs) grown on F-doped SnO(2) (FTO) glass substrates yield a benchmark specific hydrogen production rate of 122,500 μmol h(-1) g(-1), and exhibit excellent stability and recyclability.

Sterically stable liposomes improve the therapeutic effect of hepatic stimulator substance on fulminant hepatic failure in rats.

Background And Aims: Few drugs have been confirmed to be effective for fulminant hepatic failure (FHF). The purpose of this study was to prepare sterically stable liposomes (SSL) encapsulating hepatic stimulator substance (HSS) and determine their therapeutic effect on FHF.

Methods: HSS were encapsulated into SSL (HSS-SSL).

Visible emission characteristics from different defects of ZnS nanocrystals.

Various sized ZnS nanocrystals were prepared by treatment under H(2)S atmosphere. Resonance Raman spectra indicate that the electron-phonon coupling increases with increasing the size of ZnS. Surface and interfacial defects are formed during the treatment processes.

Trap states and carrier dynamics of TiO(2) studied by photoluminescence spectroscopy under weak excitation condition.

Anatase and rutile TiO(2) were investigated with photoluminescence techniques under the weak excitation condition, where trap states play a vital role in carrier dynamics. The visible emission of anatase and near-infrared (NIR) emission of rutile both exhibit extremely long lifetimes up to milliseconds. The decay processes can be well described by the power-law decay which corresponds to the trapping-detrapping effect.

[Comparative study on clinical and pathological changes of liver fibrosis with diffusion-weighted imaging].

Objective: To evaluate the clinical practical value of apparent diffusion coefficient (ADC) measurements based on diffusion-weighted MR imaging (DWI) for quantification of liver fibrosis and inflammation for hepatitis viral infection.

Methods: Diffusion-weighted MRI with parallel imaging was prospectively performed on 85 patients with chronic hepatitis and on 22 healthy volunteers within a single breath-hold using a single-shot spin-echo echo-planar sequence at b values of 100, 300, 500, 800 and 1000 s/mm2 respectively. ADC values of liver were measured with five different b values.

A new concept of desulfurization: the electrochemically driven and green conversion of SO2 to NaHSO4 in aqueous solution.

A new concept of desulfurization was developed by designing a series of electrochemical reactions to drive an SO2 absorption-and-conversion process in aqueous solution, hence the SO2 in gas was eventually converted to a valuable chemical of NaHSO4. A model experiment of chemically substantiating this concept includes two steps: (I) absorption of SO2 gas by aqueous solution and oxidation of the absorbed SO2 to SO4(2-) by air and (II) transformation of the SO4(2-) to NaHSO4. The experiment demonstrated that in Step I, the cathodic reduction of 02 from ambient air scavenged the H+ released due to the SO2 absorption and its further oxidation, which thereby were accelerated.

Effect of hepatocyte growth factor encapsulated in targeted liposomes on liver cirrhosis.

Hepatocyte growth factor (HGF) was encapsulated into sterically stabilized liposomes (SSL) in order to protect it from in vivo degradation. Cyclic Arg-Gly-Asp (RGD) peptides were combined with maleimide-[poly (ethylene glycol)]-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (MAL-PEG-DOPE) incorporated into SSL. The average percentage of HGF encapsulated into liposomes was 32.