Publications by authors named "Jianying Shangguan"
Article Synopsis
- * A 46-year-old male with a history of pancreatitis presented with nausea and vomiting, and imaging showed a cystic mass connecting the abdomen and mediastinum, compressing vital organs.
- * The cyst was confirmed as a pancreatic pseudocyst through ultrasound-guided aspiration and was treated successfully with a surgical procedure called cystojejunostomy, highlighting the rarity of such cases.
Article Synopsis
- Finerenone has shown promise in reducing cardiovascular death and renal failure risk in patients with chronic kidney disease and type 2 diabetes, prompting a study to investigate its molecular mechanisms using network pharmacology.
- Researchers utilized several databases to identify targets of finerenone and analyzed their interactions with a focus on disease-related targets, employing protein-protein interaction networks and enrichment analysis techniques.
- The study identified 111 potential cardiorenal targets and pointed to key mechanisms involving lipids, atherosclerosis, and diabetic complications, while confirming finerenone's protective effects through histopathological studies and protein expression analysis in diabetic mice.
Wilms' tumor, also called nephroblastoma, is an extremely uncommon kidney tumor of adulthood. We reported a adult man with a left kidney mass diagnosed as Wilms' tumor. Case presentation: A 25-year-old man was hospitalized due to injury of the anterior cruciate ligament of the right knee.
View Article and Find Full Text PDFMetastasis has been one of the major reasons for cancer-related mortality, with multiple genes and pathways being involved in this complex process. Given the molecular variations underlying metastasis of hepatocellular carcinoma (HCC) remains largely unknown; in our previous work, we found copying number of protocadherin-17 (PCDH-17) was significantly deleted in HCC tissues that occurred to metastasize compared with that in the primary HCC without metastasis. Therefore, we hypothesized that PCDH-17 may suppress the metastasis of HCC.
View Article and Find Full Text PDFDownregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813.
Int J Clin Exp Pathol
March 2016
Recent studies have shown that NUF2 (Ndc80 kinetochore complex component) play important roles in multiple human cancers. In our previous report, NUF2 expression was stronger in tumor tissues than in normal pancreatic tissues. However, whether and how NUF2 play a role in pancreatic cancer progression remains largely unknown.
View Article and Find Full Text PDF[Effects and mechanism of decorin on the proliferation of HuH7 hepatoma carcinoma cells in vitro].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
September 2009
Aim: To investigate the effects and mechanism of decorin( DCN) on the proliferation of HuH7 hepatoma carcinoma cell line in vitro.
Methods: Hepatoma carcinoma cells was cultured with DCN in different concentration (0, 25, 50, 75, 100, 125, 150, 200 microg/L) for different time(12, 24, 48, 72 h and 2 weeks). Cell activities were studied by MTT and clone test.