Diagnostic Performance of Multiparametric Clear Cell Likelihood Score for Characterization of Subcentimeter Solid Renal Lesions: A Multi-institutional Study.

Rationale And Objectives: Early characterization of subcentimeter (≤1cm) renal lesions is crucial for effective clinical management. This study aims to validate the diagnostic performance of the multiparametric MRI (mpMRI) clear cell likelihood score (ccLS) category in diagnosing subcentimeter clear cell renal cell carcinoma (ccRCC).

Materials And Methods: This retrospective study included consecutive patients with subcentimeter solid renal masses who underwent mpMRI between September 2009 and September 2022 at three hospitals.

Can multiparametric MRI clear cell likelihood scores differentiate fat-Poor AML from CcRCC in subcentimeter lesions?

Objective: To investigate the potential of multiparametric MRI clear cell likelihood scores (ccLS) for differentiating between fat-poor angiomyolipoma (AML) and clear cell renal cell carcinoma (ccRCC) in subcentimeter Lesions (1 cm or smaller).

Materials And Methods: This retrospective study included consecutive patients with subcentimeter renal masses who underwent multiparametric MRI between September 2009 and September 2022 across three hospitals. Clinical and MRI findings were analyzed to differentiate between fat-poor AML and ccRCC.

Tumor contour irregularity on preoperative CT predicts prognosis in renal cell carcinoma: a multi-institutional study.

Background: Radiology-based prognostic biomarkers play a crucial role in patient counseling, enhancing surveillance, and designing clinical trials effectively. This study aims to assess the predictive significance of preoperative CT-based tumor contour irregularity in determining clinical outcomes among patients with renal cell carcinoma (RCC).

Methods: We conducted a retrospective multi-institutional review involving 2218 patients pathologically diagnosed with RCC.

Radiogenomics nomogram based on MRI and microRNAs to predict microvascular invasion of hepatocellular carcinoma.

Purpose: This study aimed to develop and validate a radiogenomics nomogram for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC) on the basis of MRI and microRNAs (miRNAs).

Materials And Methods: This cohort study included 168 patients (training cohort: n = 116; validation cohort: n = 52) with pathologically confirmed HCC, who underwent preoperative MRI and plasma miRNA examination. Univariate and multivariate logistic regressions were used to identify independent risk factors associated with MVI.

Four-phase computed tomography helps differentiation of renal oncocytoma with central hypodense areas from clear cell renal cell carcinoma.

Purpose: To explore the utility of four-phase computed tomography (CT) in distinguishing renal oncocytoma with central hypodense areas from clear cell renal cell carcinoma (ccRCC).

Methods: Eighteen patients with oncocytoma and 63 patients with ccRCC presenting with central hypodense areas were included in this study. All patients underwent four-phase CT imaging including the excretory phases later than 20 min after contrast injection.

CT differentiation of the oncocytoma and renal cell carcinoma based on peripheral tumor parenchyma and central hypodense area characterisation.

Background: Although the central scar is an essential imaging characteristic of renal oncocytoma (RO), its utility in distinguishing RO from renal cell carcinoma (RCC) has not been well explored. The study aimed to evaluate whether the combination of CT characteristics of the peripheral tumor parenchyma (PTP) and central hypodense area (CHA) can differentiate typical RO with CHA from RCC.

Methods: A total of 132 tumors on the initial dataset were retrospectively evaluated using four-phase CT.

Use of specific contrast-enhanced CT regions of interest to differentiate renal oncocytomas from small clear cell and chromophobe renal cell carcinomas.

PURPOSE We aimed to examine the usefulness of utilizing a specific contrast-enhanced computed tomog raphy (CT) region of interest (ROI) to differentiate renal oncocytoma (RO) from small clear cell renal cell carcinoma (ccRCC) and chromophobe renal cell carcinoma (chRCC). METHODS A retrospective analysis of pre-contrast phase (PCP), corticomedullary phase (CMP), and nephro graphic phase (NP) contrast-enhanced CT images of the histopathologically confirmed initial cohort (27 ROs, 74 ccRCCs, and 36 chRCCs) was conducted. Small, medium, large, and whole ROIs (S-ROI, M-ROI, L-ROI, and W-ROI, respectively) were utilized for CT attenuation value of tumor (AVT), lesion-to-cortex attenuation (L/C), and heterogeneous degree of tumor (HDT) calcula tions.