Changes in phenolic compounds of Phyllanthus emblica juice during different storage temperature and pH conditions.

The aim of this experiment was to investigate the effect of storage temperature and pH on phenolic compounds of Phyllanthus emblica juice. Juice was stored at different temperatures and pH for 15 days and sampled on 2-day intervals. The browning index (BI, ABS), pH, centrifugal precipitation rate (CPR), and phenolic compounds were evaluated.

Chemical Fingerprint Analysis and Content Determination of Horned Gallnut and Bellied Gallnut in Galla Chinensis.

To establish an objective and comprehensive methodology to analyse the connections and differences between horned gallnut (HG) and bellied gallnut (BG) in Galla Chinensis (GC). The HPLC fingerprints from 15 batches of HG and 15 batches of BG were performed, and chemometric analysis including similarity analysis (SA), hierarchical clustering analysis (HCA), principal component analysis (PCA), and orthogonal partial least squares discrimination analysis (OPLS-DA) was also set up. The results showed that the similarity of all batch samples was more than 0.

Chemical fingerprint analysis and quality assessment of Tibetan medicine Triphala from different origins by high-performance liquid chromatography.

Introduction: Although the Tibetan medicine Triphala (THL) is widely used in many countries, insufficient progress has been made in quality control.

Objectives: The present study aimed to propose a methodology for quality control of THL based on HPLC fingerprinting combined with an orthogonal array design.

Methods: Seven identified peaks were used as indicators to examine the effects of temperature, extraction time, and solid-liquid ratio on the dissolution of active ingredients in THL.

Knockdown of BCL2L12 leads to cisplatin resistance in MDA-MB-231 breast cancer cells.

BCL2L12, a newly identified member of Bcl-2 family, contains a BH2 domain and a putative BH3 domain. It was found to be highly expressed in normal breast tissues, and was associated with favorable prognosis in breast cancer patients. Here, we reported that the mRNA levels of BCL2L12 and its transcript variant BCL2L12A could be upregulated upon cisplatin treatment in MDA-MB-231 breast cancer cells.

[Partial laryngectomy for ninety-eight patients with glottic carcinoma of the larynx].

Objective: To investigate the therapeutic results after various kinds of partial laryngectomy for patients with glottic carcinoma of the larynx.

Methods: From January 1980 to Mar 2004, 98 patients with glottic carcinoma of the larynx were treated by various kinds of partial laryngectomy. The types of operation varied according to stage of the lesion: vertical or frontovertical partial laryngectomy for T1b, T2 and T1a with invasion of anterior commissura, Tuker's operation or supracricoid partial laryngectomy for T1b, T2 or those with invasion of over half of contralateral cord, and extended vertical partial laryngectomy with resection of arytenoids for T3, or with invasion of ipsilateral arytenoids cartilage without involving postcricoid mucosa or posterior commissura.