Climate and landscape structure are widely recognized as the primary drivers of soil erosion; however, the spatiotemporal variability of their effects remains insufficiently understood, limiting our comprehension of the dynamic processes of soil erosion. To address this gap, this study analyzed soil erosion trends on the Loess Plateau from 2000 to 2018. extreme Gradient Boosting was used to identify key climatic and landscape structural factors, while a geographically and temporally weighted regression model was applied to assess the spatiotemporal variability of these influences.
View Article and Find Full Text PDFEur Heart J Imaging Methods Pract
July 2024
Aims: A new model of computational fluid dynamics (CFD)-based algorithm for coronary CT angiography (CCTA)-derived fractional flow reserve (FFR) (CT-FFR) analysis by expanding the coronary tree to smaller-diameter lumen (0.8 mm) using Newton-Krylov-Schwarz (NKS) method to solve the three-dimensional time-dependent incompressible Navier-Stokes equations has been developed; however, the diagnostic performance of this new method has not been sufficiently investigated. The aim of this study was to determine the diagnostic performance of a novel CT-FFR technique by expanding the coronary tree in the CFD domain.
View Article and Find Full Text PDFRationale: The prevalence of idiopathic retinitis, vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is <1/1,000,000, and it tends to occur in young women. Panretinal photocoagulation, focal laser photocoagulation, peripheral cryopexy, vitrectomy, and corticosteroid therapy are the traditional treatments. We reported a case of a senile patient with IRVAN syndrome who presented with severe exudation in both eyes and macular edema in the left eye, successfully treated by serial intravitreal aflibercept injections.
View Article and Find Full Text PDFIEEE/ACM Trans Comput Biol Bioinform
September 2024
AutoDock Vina and its derivatives have established themselves as a prevailing pipeline for virtual screening in contemporary drug discovery. Our Vina-GPU method leverages the parallel computing power of GPUs to accelerate AutoDock Vina, and Vina-GPU 2.0 further enhances the speed of AutoDock Vina and its derivatives.
View Article and Find Full Text PDFGlobal climate change has necessitated the implementation of green infrastructure that is resilient in a manner of sustainable development. The current understanding of green infrastructure resilience is hindered by the divergence of generic properties and performance in adapting to uncertain disturbances. This study develops an operational methodology that integrates structural and functional properties of green infrastructure, and their connections to shape the general resilience.
View Article and Find Full Text PDFUltra-High Toughness Cementitious Composite (UHTCC) represents a composite material meticulously engineered on the foundation of micromechanical principles. The multi-crack cracking and strain-hardening characteristics of UHTCC enable it to be applied to orthotropic steel decks to control the crack width. Different from most studies which only focus on hybrid fiber or fatigue characteristics, this paper studies the influence of hybrid fiber content on static mechanical properties, flexural toughness, and flexural fatigue characteristics of UHTCC under different stress levels.
View Article and Find Full Text PDFInorganic metal sulfides have received extensive investigation as anode materials in lithium-ion batteries (LIBs). However, applications of crystalline organic hybrid metal sulfides as anode materials in LIBs are quite rare. In addition, combining the nanoparticles of crystalline organic hybrid metal sulfides with conductive materials is expected to enhance the electrochemical lithium storage performance.
View Article and Find Full Text PDFAs a new type of backfill material, Self-compacting solidified soil (SCSS) takes the abandoned slurry of cast-in-place piles after dewatering and reduction as the main raw material, which brings a problem of coordinating the working performance with the mechanical property under the condition of high mobility. In this paper, hydroxypropyl methyl cellulose (HPMC) and metakaolin were introduced as additives to solve this problem. First, the workability and mechanical properties of SCSS were regulated and optimized by means of the water seepage rate test, the flowability test, and the unconfined compressive strength test.
View Article and Find Full Text PDFMotivation: Deep graph learning (DGL) has been widely employed in the realm of ligand-based virtual screening. Within this field, a key hurdle is the existence of activity cliffs (ACs), where minor chemical alterations can lead to significant changes in bioactivity. In response, several DGL models have been developed to enhance ligand bioactivity prediction in the presence of ACs.
View Article and Find Full Text PDFVery high-resolution remote sensing images hold promising applications in ground observation tasks, paving the way for highly competitive solutions using image processing techniques for land cover classification. To address the challenges faced by convolutional neural network (CNNs) in exploring contextual information in remote sensing image land cover classification and the limitations of vision transformer (ViT) series in effectively capturing local details and spatial information, we propose a local feature acquisition and global context understanding network (LFAGCU). Specifically, we design a multidimensional and multichannel convolutional module to construct a local feature extractor aimed at capturing local information and spatial relationships within images.
View Article and Find Full Text PDFThe continuous advancement in the field of flexible and wearable electronics has led to increased research interest in safe, low-cost, and flexible zinc-ion batteries, particularly with a focus on flexible electrolytes. In this study, we present a leather gel electrolyte (LGE) that offers robust mechanical properties and an excellent electrochemical performance. LGE exhibits an ionic conductivity of 1.
View Article and Find Full Text PDFA Prussian blue analogue was synthesized using biomass leather waste as a precursor by doping with Co ions. This material, demonstrates good performance in both the oxygen reduction reaction and oxygen evolution reaction, and exhibits excellent charge-discharge performance and stability in zinc-air batteries.
View Article and Find Full Text PDFWith the extensive industrialization and urbanization taking place in China during the recent decades, land use throughout the country has experienced profound changes influenced not only by the demand for population growth and living standard improvement but also by the constraints of series of land use policies. However, whether the conflict between the expansion of settlement land (SL) and the loss of cultivated land (CL) have been resolved at the national scale or transferred between the local regions remains unclear. Based on yearly ESA CCI land use and land cover products from 1992 to 2020, the long-term trends of quantity and spatial pattern of SL expansion and CL change in China from national and local views were investigated using trend statistic methods, and finally a comprehensive zoning framework was proposed to recognize the trade-off and synergies relationships between SL expansion and CL change.
View Article and Find Full Text PDFSite specific biotinylation of AviTagged recombinant proteins using BirA enzyme is a widely used protein labeling technology. However, due to the incomplete biotinylation reactions and the lack of a purification method specific for the biotinylated proteins, it is challenging to purify the biotinylated sample when mixed with the non-biotinylated byproduct. Here, we have developed a monoclonal antibody that specifically recognizes the non-biotinylated AviTag but not the biotinylated sequence.
View Article and Find Full Text PDFThe androgen receptor (AR) is the central determinant of prostate tissue identity and differentiation, controlling normal, growth-suppressive prostate-specific gene expression . It is also a key driver of prostate tumorigenesis, becoming "hijacked" to drive oncogenic transcription . However, the regulatory elements determining the execution of the growth suppressive AR transcriptional program, and whether this can be reactivated in prostate cancer (PCa) cells remains unclear.
View Article and Find Full Text PDFPeerJ Comput Sci
January 2024
Lane detection under extreme conditions presents a highly challenging task that requires capturing each crucial pixel to predict the complex topology of lane lines and differentiate the various lane types. Existing methods predominantly rely on deep feature extraction networks with substantial parameters or the fusion of multiple prediction modules, resulting in large model sizes, embedding difficulties, and slow detection speeds. This article proposes a Proportional Feature Pyramid Network (P-FPN) through fusing the weights into the FPN for lane detection.
View Article and Find Full Text PDFPurpose: The purpose of this study is to report the clinical characteristics of macular telangiectasia type 2 (MacTel 2) in Taiwan.
Materials And Methods: Retrospective analysis of patients diagnosed with MacTel 2 over a 7-year period in Changhua Christian Hospital. Best-corrected visual acuity (BCVA), fundus photography, fluorescein angiography, optical coherence tomography (OCT), and OCT angiography (OCTA) images were reviewed.
Medicine (Baltimore)
November 2023
Introduction: Esophageal cancer is the seventh most common malignancy worldwide and the sixth leading cause of cancer mortality with an overall survival rate of <20%. Esophageal cancer frequently metastasizes to distant lymph nodes, lungs, liver, and bones. Cerebral metastases originating from esophageal cancer are rare and often carry a poor prognosis as do most all metastatic lesions in esophageal cancer.
View Article and Find Full Text PDFGiven the rising prevalence of patients with diabetes and increasing treatment burden for patients with vision-threatening diabetic macular edema (DME), we aimed to explore the efficacy of modified early intensive and treat-and-extend regimen of anti-vascular endothelial growth factor (VEGF) therapy under the Taiwan National Insurance Bureau reimbursement policy. We obtained data on 69 eyes treated with initial 4-monthly intravitreal injections of aflibercept or ranibizumab, plus individualized treat-and-extend regimen. At 12 months, the mean (SD) change in LogMAR best corrected visual acuity from baseline was - 0.
View Article and Find Full Text PDFHigh-entropy oxides (HEOs) can be well suited for lithium-ion battery anodes because of their multi-principal synergistic effect and good stability. The appropriate selection and combination of elements play a crucial role in designing conversion-type anode materials with outstanding electrochemical performance. In this study, we have successfully built a single-phase spinel-structured HEO material of (MnFeCoCrZn)O (HEO-MFCCZ).
View Article and Find Full Text PDFIEEE/ACM Trans Comput Biol Bioinform
December 2023
Simulated Annealing (SA) algorithm is not effective with large optimization problems for its slow convergence. Hence, several parallel Simulated Annealing (pSA) methods have been proposed, where the increase of searching threads can boost the speed of convergence. Although satisfactory solutions can be obtained by these methods, there is no rigorous mathematical analyses on their effectiveness.
View Article and Find Full Text PDFRhegmatogenous retinal detachment (RRD) is a significant cause of vision loss and requires appropriate surgical intervention. There are several approaches available, including observation, laser demarcation, pneumatic retinopexy, scleral buckling, and pars plana vitrectomy, which are chosen based on patient condition, surgeon experience, and national health insurance policies. Despite the various options, there is still no consensus on the optimal intervention.
View Article and Find Full Text PDFUnravelling the evolution of landscape patterns is essential to understand regional socio-ecological processes and to solve conflicts between environment protection and human development. However, the role of landscape transition in regional landscape pattern evolution remains unclear. Taking 325 county-level areas in the middle reaches of the Yangtze River (MRYR) as an example, this study explored the spatiotemporal associations between landscape quantity and pattern from the 1970s to 2020.
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