The prognosis and treatment consideration for non-small cell lung carcinoma patients with tumor size of >2.0-3.0 cm and visceral pleural invasion: a SEER-based study.

Background: Lung cancer is the most prevailing oncological disease worldwide. Visceral pleural invasion (VPI) has been proven to be a poor prognosis factor for early-stage non-small cell lung carcinoma (NSCLC) patients. However, there remains some debate regarding whether NSCLC patients with tumor size (TS) ranging from >2.

An Association between Bilirubin and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus: An Effect Modification by Nrf2 Polymorphisms.

Background: Diabetic retinopathy (DR) is a persistent microvascular complication associated with diabetes, and it constitutes a significant cause of visual impairment and blindness.

Aims: This study aimed to assess the correlation between serum bilirubin levels and the prevalence of DR in patients diagnosed with type 2 diabetes mellitus (T2DM). Additionally, we sought to establish whether the polymorphisms of Nuclear Factor E2-Related Factor 2 (Nrf2) might modify this relationship.

Interaction of proteinuria and diabetes on the risk of cardiovascular events: a prospective cohort CKD-ROUTE study.

Objective: We evaluated the interaction of urinary protein-to-creatinine ratio (UPCR) with diabetes on the risk of cardiovascular events in a cohort study.

Methods: The study population consisted of 639 participants with chronic kidney disease (CKD) stages 2-5, enrolled between 2010 and 2011 in Japan. Cox proportional hazards models were used to evaluate the independent and combined effects of the UPCR and diabetes on cardiovascular events.

Patterns of regional lymph node metastasis predict postoperative overall survival and disease-free survival in locally advanced esophageal squamous cell carcinoma.

Background: Lymph nodal characteristics are highly significant in predicting the survival of patients with esophageal squamous cell carcinoma (ESCC). However, there is currently a scarcity of studies examining their role in locally advanced ESCC. In the present study, we attempted to depict the patterns of regional lymph node metastasis and investigate their predictive potential in locally advanced ESCC.

Assessment of Quality of Reporting in Randomized Controlled Trials of Moxibustion for Chronic Diseases Using the Consolidated Standards of Reporting Trials and Standards for Reporting Interventions in Clinical Trials of Moxibustion Statements.

Introduction: Moxibustion is clinically used for treating various chronic diseases; however, the reporting quality of current published RCTs of moxibustion is unclear. The objective of this study was to assess the reporting quality of RCTs focusing on moxibustion as a treatment for chronic diseases.

Methods: Seven databases were searched to identify relevant RCTs.

[Advances in mechanisms of biofilm formation and drug resistance of ].

is a common pathogenic bacterium. However, due to the abuse of antibiotics, multiple drug-resistant . (DR .

Risk of Asthma and Allergies in Children Delivered by Cesarean Section: A Comprehensive Systematic Review.

Background: It is unclear whether cesarean delivery increases the risk of allergic diseases in offspring.

Objective: To investigate the association between cesarean delivery and the risk of allergic diseases in offspring.

Methods: We searched PubMed, Embase, and the Cochrane Library for relevant studies up to October 12, 2023.

Safety of medicinal and edible herbs from fruit sources for human consumption: A systematic review.

Ethnopharmacological Relevance: Medicinal and edible herbs from fruit sources have been increasingly used in traditional Chinese medicine dietotherapy. There are no restrictions on who could consume the medicinal and edible fruits or on the dosage of consumption. However, their safety for human consumption has yet to be established.

Clinical relevance of somatic mutations in Chinese lung adenocarcinoma and their prognostic implications for survival.

Background: To comprehensively elucidate the genomic and mutational features of lung cancer cases, and lung adenocarcinoma (LUAD), it is imperative to conduct ongoing investigations into the genomic landscape. In this study, we aim to analyze the somatic mutation profile and assessed the significance of these informative genes utilizing a retrospective LUAD cohort.

Methods: A total of 247 Chinese samples were analyzed to exhibit the tumor somatic genomic alterations in patients with LUAD.

Sublobectomy and lymph node sampling are adequate for patients with invasive lung adenocarcinoma presenting as pure ground glass nodules.

Purpose: In this study, we aimed to investigate the prognosis of invasive lung adenocarcinoma that manifests as pure ground glass nodules (pGGNs) and confirm the effectiveness of sublobectomy and lymph node sampling in patients with pGGN-featured invasive adenocarcinoma (IAC).

Materials And Methods: We retrospectively enrolled 139 patients with pGGN-featured IAC, who underwent complete resection in two medical institutions between January 2011 and May 2022. Stratification analysis was conducted to ensure balanced baseline characteristics among the patients.

Targeting the aryl hydrocarbon receptor with FICZ regulates IL-2 and immune infiltration to alleviate Hashimoto's thyroiditis in mice.

Hashimoto's thyroiditis (HT) is the most frequent autoimmune disorder. Growing work points to the involvement of aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor, in the regulation of immune homeostasis. However, the roles of AhR and its ligands in HT remains unclear.

Giant cell tumor of soft tissue involving thyroid gland: a case report and review of the literature.

Background: Giant cell tumor of soft tissue is a low malignant uncommon neoplasm, with histologic features and immunophenotype similar to its bone counterpart. Primary giant cell tumor of soft tissue in the thyroid gland is considered an exceedingly rare entity.

Case Presentation: We describe a case of primary thyroid giant cell tumor of soft tissue in a 69-year-old Chinese female patient.

Transforming electrochemical hydrogen Production: Tannic Acid-Boosted CoNi alloy integration with Multi-Walled carbon nanotubes for advanced bifunctional catalysis.

The dimensions of alloy nanoparticles or nanosheets have emerged as a critical determinant for their prowess as outstanding electrocatalysts in water decomposition. Remarkably, the reduction in nanoparticle size results in an expanded active specific surface area, elevating reaction kinetics and showcasing groundbreaking potential. In a significant leap towards innovation, we introduced tannic acid (TA) to modify multi-walled carbon nanotubes (MWCNTs) and CoNi alloys.

A novel bi-functional cold-adaptive chitinase from Chitinilyticum aquatile CSC-1 for efficient synthesis of N-acetyl-D-glucosaminidase.

In order to better utilize chitinolytic enzymes to produce high-value N-acetyl-D-glucosamine (GlcNAc) from chitinous waste, there is an urgent need to explore bi-functional chitinases with exceptional properties of temperature, pH and metal tolerance. In this study, we cloned and characterized a novel bi-functional cold-adaptive chitinase called CaChi18A from a newly isolated strain, Chitinilyticum aquatile CSC-1, in Bama longevity village of Guangxi Province, China. The activity of CaChi18A at 50 °C was 4.

Paint sludge derived activated carbon encapsulating with cobalt nanoparticles for non-radical activation of peroxymonosulfate.

Industrial solid waste management and recycling are important to environmental sustainability. In this study, cobalt (Co) nanoparticles encapsulated in paint sludge-derived activated carbon (AC) were fabricated. The Co-AC possessed high conductivity, magnetic properties and abundant metal oxide impurities (TiAlSiO), which was applied as multifunctional catalyst for peroxymonosulfate (PMS) activation.

Multi-omics analysis reveals the molecular basis of flavonoid accumulation in fructus of Gardenia (Gardenia jasminoides Ellis).

Background: The fruits of Gardenia are rich in flavonoids and geniposides, which have various pharmacological effects such as antioxidant, anti-inflammatory and anticancer. In this study, we analyzed the transcriptome and metabolome of gardenia peel and kernel at different growth stages, revealed the regulatory network related to flavonoid synthesis, and identified the key regulatory genes.

Results: The results showed that in terms of flavonoid metabolic pathways, gardenia fruits mainly synthesized cinnamic acid through the phenylpropanoid pathway, and then synthesized flavonoids through the action of catalytic enzymes such as 4-coumaroyl-CoA ligase, chalcone synthase, chalcone isomerase and flavanol synthase, respectively.

Role of the tripartite motif-containing (TRIM) family of proteins in insulin resistance and related disorders.

Emerging evidence suggests that the ubiquitin-mediated degradation of insulin-signalling-related proteins may be involved in the development of insulin resistance and its related disorders. Tripartite motif-containing (TRIM) proteins, a superfamily belonging to the E3 ubiquitin ligases, are capable of controlling protein levels and function by ubiquitination, which is essential for the modulation of insulin sensitivity. Recent research has indicated that some of these TRIMs act as key regulatory factors of metabolic disorders such as type 2 diabetes mellitus, obesity, nonalcoholic fatty liver disease, and atherosclerosis.

Structural and Physical Properties of Alginate Pretreated by High-Pressure Homogenization.

To develop a high-efficient extraction method, we investigated the use of high-pressure homogenization (HPH) as a novel pretreatment technology for the extraction of sodium alginate (SA) from . After the single-factor experiment, the results demonstrated that under the conditions of 100 MPa HPH pressure, 4 cycles, pH 6.0, and 0.

Controlling the electronic structure of Fe-MOF electrocatalyst for enhanced water splitting and urea oxidation: A plasma-assisted approach.

The design of high-performance electrocatalysts for water splitting and urea oxidation reactions requires effective regulation of their electronic structure and electrochemical surface area (ECSA). In this study, we developed an in-situ grown Fe-MOF electrocatalyst on Fe foam (FF) by using a combination of easy hydrothermal synthesis and advanced plasma technology (Fe-MOF/FF). By varying the plasma treatment time, we could tailor the surface morphology and electronic structure of the Fe-MOF/FF microrods.