Single-cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment.

The tumor microenvironment (TME) directly determines patients' outcomes and therapeutic efficiencies. An in-depth understanding of the TME is required to improve the prognosis of patients with cervical cancer (CC). This study conducted single-cell RNA and TCR sequencing of six-paired tumors and adjacent normal tissues to map the CC immune landscape.

Microendoscopy in vivo for the pathological diagnosis of cervical precancerous lesions and early cervical cancer.

Background: Cervical cancer is an important public health problem. Conventional colposcopy is inefficient in the diagnosis of cervical lesions and massive biopsies result in trauma. There is an urgent need for a new clinical strategy to triage women with abnormal cervical screening results immediately and effectively.

Electrochemical conversion of CO into value-added carbon with desirable structures molten carbonates electrolysis.

Direct conversion of CO to high value-added carbon products based on molten salt electrochemistry has been proven to be a feasible approach to solve the climate problem and achieve carbon neutrality. In this work, carbon nanotubes (CNTs), carbon spheres (CSs) and honeycomb carbon are synthesized by electrolysis of a single or multiple alkali metal carbonate electrolyte. The elemental composition, morphology and structure, crystallinity and graphitization degree of carbon products are characterized by electron dispersive spectroscopy (EDS), scanning electron microscopy (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD) and Raman microspectroscopy (RAM).