Publications by authors named "Jianqiang Niu"
The therapeutic potential of autologous stem cell transplantation for heart repair diminishes in the elderly due to stem cell aging. Rejuvenating aged stem cells to enhance their protective effects on injured cardiomyocytes is crucial for aging patients with heart failure. In this study, we aimed to investigate whether neuron-derived neurotrophic factor (NDNF) over-expression improves the protective effect of aged stem cells for injured cardiomyocytes and explore the underlying mechanism.
View Article and Find Full Text PDFPorcine reproductive and respiratory syndrome virus (PRRSV) has a high degree of genetic variation. In this study, we characterized the genetic variation and evolutionary relationships among circulating PRRSV strains in southern China. We analyzed 29 NSP2 strains and 150 ORF5 strains from clinical samples collected in southern China during 2007-2014.
View Article and Find Full Text PDFThe spike gene of porcine epidemic diarrhea virus (PEDV) was sequenced from 55 South China field strains isolated from pigs with symptoms of diarrhea. The sequences were compared within the set of field strains as well as with reference strains available in GenBank. Within the 55 South China PEDV field strains, the deduced amino acid sequence identities ranged from 93.
View Article and Find Full Text PDFArticle Synopsis
- - Outbreaks of pseudorabies (PR) have been affecting the swine industry in southern China since late 2011, prompting concerns especially for vaccinated pigs.
- - Researchers isolated 11 pseudorabies virus (PRV) strains from Guangdong province and found notable genetic changes, particularly in viral genes like gD, gE, gI, and PK, compared to other global isolates.
- - Phylogenetic analysis indicates that these strains form a distinct group and possess unique molecular signatures, suggesting they are new variants of PRV prevalent in China.
[Effects of matrine on proliferation and apoptosis of human renal cell carcinoma cell line GRC-1].
Zhong Xi Yi Jie He Xue Bao
July 2006
Objective: To observe the effects of matrine on proliferation and apoptosis of human renal cell carcinoma cell line GRC-1 in vitro, and to explore its mechanism.
Methods: The human renal cell carcinoma cell line GRC-1 was treated with matrine of different concentrations for 24, 48, 72 and 96 h respectively. The MTT assay was used to evaluate the cytotoxic effects of matrine on GRC-1 cells.