Study on risk factors of preoperative deep vein thrombosis in patients with lower limb fractures and construction and validation of risk prediction nomogram model.

Background: To explore the correlation between the levels of D-dimer (D-D), fibrinogen (FIB), fibrinogen degradation products (FDP) and platelets (PLT) in peripheral blood of patients with lower limb fractures and the formation of deep vein thrombosis in lower limbs, and to establish a new thrombosis prediction model for patients with lower limb fractures.

Methods: The patients were divided into DVT group and non DVT group according to whether there was deep vein thrombosis of the lower extremity. The differences in the levels of D-D, FIB, FDP and platelets between the two groups were analyzed and compared.

Factors associated with new fractures in adjacent vertebrae after percutaneous vertebroplasty for osteoporotic vertebral compression fractures.

Objective: To investigate the predictive factors for new fractures in adjacent vertebrae after percutaneous vertebroplasty for osteoporotic vertebral compression fractures, thus providing new insights for clinical practice.

Methods: A total of 124 patients were retrospectively included in this study. Based on the presence of new vertebral compression fractures in adjacent vertebrae postoperatively, patients were divided into a non-fracture group and a new-fracture group.

Near complete assembly of Pyricularia penniseti infecting Cenchrus grass identified its eight core chromosomes.

Fungi from the Pyricularia genus cause blast disease in many economically important crops and grasses, such as wheat, rice, and Cenchrus grass JUJUNCAO. Structure variation associated with the gain and loss of effectors contributes largely to the adaptive evolution of this fungus towards diverse host plants. A telomere-to-telomere genome assembly would facilitate the identification of genome-wide structural variations through comparative genomics.

Influence of photosynthetic active radiation on sap flow dynamics across forest succession stages in Dinghushan subtropical forest ecosystem.

With the intensification of global change, forests are subjected to varying degrees of drought or high-temperature stress, which has an indelible impact on the growth of trees. However, knowledge on the response of sap flow to environmental changes in different types of forests is still rare, especially in China's subtropical forest ecosystem. Consequently, studying how different tree species regulate their sap flow in response to shifting environmental conditions is essential for understanding forest transpiration, water use efficiency, and drought stress resilience.

An innovative deformation coordination method for analyzing distortion effects on box girders.

A deformation coordination method is proposed in this study to account for the distortion effects on a box girder. The differential equation for distortion in vertical web box girders is derived based on the deformation coordination condition of the distortion angle, considering both external loads and internal forces. Subsequently, a comparative analysis is conducted to explore the similarities and differences between the differential equations derived from the proposed deformation coordination method, the plate element analysis method and the total potential energy variation method.

Lack of clinical benefit from preoperative short-term parenteral nutrition on the clinical prognosis of patients treated with radical gastrectomy for gastric cancer: a two-center retrospective study based on propensity score matching analysis.

Background: Preoperative nutritional support studies for patients undergoing gastrointestinal (GI) surgery mostly focused on enteral nutrition (EN) or long-term (≥7 days) parenteral nutrition (PN). Some studies also found that preoperative short-term PN could improve the postoperative short-term nutritional status of tumor patients. But whether short-term PN support (1-6 days) before surgery can improve the prognosis of patients undergoing surgery for gastric cancer (GC) remains unclear.

The cyclic AMP (cAMP) phosphodiesterase CpdA required for growth, biofilm formation, motility and pathogenicity of Edwardsiella piscicida.

Edwardsiella piscicida is a severe fish pathogen with wide host range, causing the huge economic losses in the aquaculture industry. Cyclic adenosine monophosphate (cAMP) as an important second messenger regulates the physiological and behavioral responses to environmental cues in eukaryotic and prokaryotic. The intracellular level of cAMP for effective activity is tightly controlled by the synthesis of adenylate cyclase, excretion and degradation of phosphodiesterase.

Copper-Catalyzed α-Arylation of Nitroalkanes with (Hetero)aryl Bromides/Iodides.

α-Aryl substituted nitroalkanes are valuable synthetic building blocks that can be easily converted into α-aryl substituted aldehydes, ketones, carboxylic acids, as well as amines. Herein, an efficient Cu/oxalamide-catalyzed coupling between nitroalkanes and (hetero)aryl halides (Br, I) was developed to direct access highly diverse α-aryl substituted nitroalkanes. Compared with the current state of art, this protocol is more environmentally friendly and practical for synthetic chemists.

Computer-Aided Diagnosis of Laryngeal Cancer Based on Deep Learning with Laryngoscopic Images.

Laryngeal cancer poses a significant global health burden, with late-stage diagnoses contributing to reduced survival rates. This study explores the application of deep convolutional neural networks (DCNNs), specifically the Densenet201 architecture, in the computer-aided diagnosis of laryngeal cancer using laryngoscopic images. Our dataset comprised images from two medical centers, including benign and malignant cases, and was divided into training, internal validation, and external validation groups.

Effect of far-infrared therapy device on arteriovenous fistula maturation and lifespan in hemodialysis patients: a randomized controlled clinical trial.

Introduction: Arteriovenous fistula (AVF) is the first choice of vascular access for hemodialysis treatment, and its surgical maturity rate is not high, and its postoperative complications (mostly stenosis) significantly shorten its life. At present, there are few studies on treatment methods to improve the maturity and survival of AVF. In this study, the effect of far infrared therapy (FIR) on the maturity and longevity of arteriovenous fistula in hemodialysis patients was discussed, and the protective mechanism of AVF induced by FIR therapy was explored, aiming at exploring a new treatment method.

The effects of propranolol on the biology and Notch signaling pathway of human umbilical vein endothelial cells.

Background: Propranolol is the first choice for treating infantile hemangioma (IH). How propranolol works in IH remains unclear. Infantile hemangioma endothelial cells (HemECs) express Notch1, Jagged, Hey1, and other molecules in the Notch pathway, suggesting that Notch pathway-related molecules play an important role in affecting vascular endothelial cell proliferation.

Screening of linear B-cell epitopes and its proinflammatory activities of outer membrane protein P2.

is a commensal organism of the upper respiratory tract of pigs, but virulent strains can cause Glässer's disease, resulting in significant economic losses to the swine industry. OmpP2 is an outer membrane protein of this organism that shows considerable heterogeneity between virulent and non-virulent strains, with classification into genotypes I and II. It also acts as a dominant antigen and is involved in the inflammatory response.

Analysis of safety and efficacy of conservative treatment and endovascular treatment in patients with spontaneous isolated mesenteric artery dissection.

Background: Spontaneous isolated superior mesenteric artery dissection (SISMAD) is a rare disease with abdominal pain as the main clinical manifestation, but its optimal treatment strategy has not yet been determined. Based on this, this study explored a safe and effective treatment method by analyzing and comparing the safety and efficacy of conservative treatment and endovascular treatment in SISMAD patients.

Methods: The clinical and imaging data and treatment effects of 85 patients with SISMAD who were admitted to the General Surgery Department of the 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from January 2008 to December 2020 were retrospectively analyzed.

Based on CT at the third lumbar spine level, the skeletal muscle index and psoas muscle index can predict osteoporosis.

Background: With the increasing number of studies on osteoporosis and muscle adipose tissue, existing studies have shown that skeletal muscle tissue and adipose tissue are closely related to osteoporosis by dual-energy x-ray absorptiometry (DXA) measurement. However, few studies have explored whether the skeletal muscle and adipose tissue index measured at the lumbar spine 3 (L3) level are closely related to bone mineral density (BMD) and can even predict osteoporosis. Therefore, this study aimed to prove whether skeletal muscle and adipose tissue index measured by computed tomography (CT) images based on a single layer are closely related to BMD.

Global leaders malnutrition initiative-defined malnutrition affects long-term survival of different subgroups of patients with gastric cancer: A propensity score-matched analysis.

As defined by the Global Leaders Malnutrition Initiative (GLIM), malnutrition is strongly associated with a lower quality of life and poor prognosis in gastric cancer patients. However, few studies have precisely explored the predictors of malnutrition, as defined by the GLIM, for overall survival (OS) after gastric cancer surgery in subgroups of patients stratified according to population characteristics. Our research aimed to analyze whether the predictors of malnutrition defined by the GLIM for postoperative OS in gastric cancer patients differ across subgroups.

NHC-Ni(II)-catalyzed cyclopropene-isocyanide [5 + 1] benzannulation.

Isocyanides are common compounds in fine and bulk chemical syntheses. However, the direct addition of isocyanide to simple unactivated cyclopropene via transition metal catalysis is challenging. Most of the current approaches focus on 1,1-insertion of isocyanide to M-R or nucleophilc insertion.

Progressive Transfer Learning.

Model fine-tuning is a widely used transfer learning approach in person Re-identification (ReID) applications, which fine-tuning a pre-trained feature extraction model into the target scenario instead of training a model from scratch. It is challenging due to the significant variations inside the target scenario, e.g.

Unsupervised Discrete Hashing With Affinity Similarity.

In recent years, supervised hashing has been validated to greatly boost the performance of image retrieval. However, the label-hungry property requires massive label collection, making it intractable in practical scenarios. To liberate the model training procedure from laborious manual annotations, some unsupervised methods are proposed.

Systemic Corticosteroids and Mortality in Severe and Critical COVID-19 Patients in Wuhan, China.

Background: Systemic corticosteroids are now recommended in many treatment guidelines, although supporting evidence is limited to 1 randomized controlled clinical trial (RECOVERY).

Objective: To identify whether corticosteroids were beneficial to COVID-19 patients.

Methods: A total of 1514 severe and 249 critical hospitalized COVID-19 patients from 2 medical centers in Wuhan, China.

Characteristics of photonic jets generated by a dielectric sphere illuminated by a Gaussian beam.

Photonic jets (PJs) formed on the shadow side of micro-sized dielectric spheres excited by focused Gaussian beams are investigated within the framework of the generalized Lorenz-Mie theory (GLMT). The intrinsic advantages of rapidity and high accuracy of the GLMT in calculations enable us to conduct a systematic study of PJs at a low cost and a high reliability. To reveal the influence of beam parameters on the properties of PJs, numerical results concerning variations of key parameters of PJs, including the maximal intensity, the focal distance, which is linked to the position of maximal intensity, and longitudinal and transversal dimensions are presented with the change of the beam waist radius and the focal center location of the Gaussian beam.

Elevation of blood glucose level predicts worse outcomes in hospitalized patients with COVID-19: a retrospective cohort study.

Introduction: With intense deficiency of medical resources during COVID-19 pandemic, risk stratification is of strategic importance. Blood glucose level is an important risk factor for the prognosis of infection and critically ill patients. We aimed to investigate the prognostic value of blood glucose level in patients with COVID-19.

SIF: Self-Inspirited Feature Learning for Person Re-identification.

The re-identification (ReID) task has received increasing studies in recent years and its performance has gained significant improvement. The progress mainly comes from searching for new network structures to learn person representations. Most of these networks are trained using the classic stochastic gradient descent optimizer.