Co-Atomic Interface Minimizing Charge Transfer Barrier in Polytypic Perovskites for CO Photoreduction.

Heterojunctions, known for their decent separation of photo-generated electrons and holes, are promising for photocatalytic CO reduction. However, a significant obstacle in traditional post-assembled heterojunctions is the high interfacial barrier for charge transfer caused by atomic lattice mismatch at multiphase interfaces. Here, as research prototypes, the study creates a lattice-matched co-atomic interface within CsPbBr-CsPbBr polytypic nanocrystals (113-125 PNs) through the proposed in situ hybrid strategy to elucidate the underlying charge transfer mechanism within this unique interface.

Strong Dipole Moments from Ferrocene Methanol Clusters Boost Exciton Dissociation in Quantum-Confined Perovskite for CO Photoreduction.

Perovskite nanocrystals (PCNs) exhibit a significant quantum confinement effect that enhances multiexciton generation, making them promising for photocatalytic CO reduction. However, their conversion efficiency is hindered by poor exciton dissociation. To address this, we synthesized ferrocene-methanol-functionalized CsPbBr (CPB/FcMeOH) using a ligand engineering approach.

Therapeutic efficacy of recombinant human growth hormone in children with different etiologies of dwarfism from a pharmacoeconomic point of view.

Treatment outcomes for different causes of childhood dwarfism vary widely, and there are no studies on the economic burden of treatment in relation to outcomes. This paper compared the efficacy and healthcare costs per unit height of recombinant human growth hormone (rhGH) for the treatment of growth hormone deficiency (GHD) and idiopathic short stature (ISS) with a view to providing a more cost-effective treatment option for children. We retrospectively analyzed 117 cases (66 cases of GHD and 51 cases of ISS) of short-stature children who first visited Weifang People's Hospital between 2019.

In situ fabrication of atomically adjacent dual-vacancy sites for nearly 100% selective CH production.

The photocatalytic CO-to-CH conversion involves multiple consecutive proton-electron coupling transfer processes. Achieving high CH selectivity with satisfactory conversion efficiency remains challenging since the inefficient proton and electron delivery path results in sluggish proton-electron transfer kinetics. Herein, we propose the fabrication of atomically adjacent anion-cation vacancy as paired redox active sites that could maximally promote the proton- and electron-donating efficiency to simultaneously enhance the oxidation and reduction half-reactions, achieving higher photocatalytic CO reduction activity and CH selectivity.

Boosting exciton dissociation and charge transfer in CsPbBr QDs via ferrocene derivative ligation for CO photoreduction.

Photo-catalytic CO reduction with perovskite quantum dots (QDs) shows potential for solar energy storage, but it encounters challenges due to the intricate multi-electron photoreduction processes and thermodynamic and kinetic obstacles associated with them. This study aimed to improve photo-catalytic performance by addressing surface barriers and utilizing multiple-exciton generation in perovskite QDs. A facile surface engineering method was employed, involving the grafting of ferrocene carboxylic acid (FCA) onto CsPbBr (CPB) QDs, to overcome limitations arising from restricted multiple-exciton dissociation and inefficient charge transfer dynamics.

Ligand-mediated exciton dissociation and interparticle energy transfer on CsPbBr perovskite quantum dots for efficient CO-to-CO photoreduction.

Perovskite quantum dots (PQDs) hold immense potential as photocatalysts for CO reduction due to their remarkable quantum properties, which facilitates the generation of multiple excitons, providing the necessary high-energy electrons for CO photoreduction. However, harnessing multi-excitons in PQDs for superior photocatalysis remains challenging, as achieving the concurrent dissociation of excitons and interparticle energy transfer proves elusive. This study introduces a ligand density-controlled strategy to enhance both exciton dissociation and interparticle energy transfer in CsPbBr PQDs.

Halogen-Site Regulation in CsBiX Quantum Dots for Efficient and Selective Oxidation of Benzyl Alcohol Driven by Solar Light.

Sluggish charge kinetics and low selectivity limit the solar-driven selective organic transformations under mild conditions. Herein, an efficient strategy of halogen-site regulation, based on the precise control of charge transfer and molecule activation by rational design of CsBiX quantum dots photocatalysts, is proposed to achieve both high selectivity and yield of benzyl-alcohol oxidation. In situ PL spectroscopy study reveals that the Bi─Br bonds formed in the form of Br-associated coordination can enhance the separation and transfer of photoexcited carriers during the practical reaction.

Comparison of haploidentical-allogeneic hematopoietic stem cell transplantation and intensive immunosuppressive therapy for patients with severe aplastic anemia with an absolute neutrophil count of zero: a retrospective study.

A retrospective analysis was conducted based on the clinical data from 60 patients older than 16 years from January 2016 to January 2021. All the patients were newly diagnosed with severe aplastic anemia (SAA) with an absolute neutrophil count (ANC) of zero. We compared the hematological response and survival of haploidentical-allogeneic hematopoietic stem cell transplantation (HID-HSCT) (n = 25) and intensive immunosuppressive therapy (IST) (n = 35) treatments.

Nitrogen-Centered Lactate Oxidase Nanozyme for Tumor Lactate Modulation and Microenvironment Remodeling.

Designing nanozymes that match natural enzymes have always been an attractive and challenging goal. In general, researchers mainly focus on the construction of metal centers and the control of non-metallic ligands of nanozyme to regulate their activities. However, this is not applicable to lactate oxidase, i.

Piezoelectric Nanozyme for Dual-Driven Catalytic Eradication of Bacterial Biofilms.

Catalytic nanomedicine can in situ catalytically generate bactericidal species under external stimuli to defend against bacterial infections. However, bacterial biofilms seriously impede the catalytic efficacy of traditional nanocatalysts. In this work, MoSe nanoflowers (NFs) as piezoelectric nanozymes were constructed for dual-driven catalytic eradication of multi-drug-resistant bacterial biofilms.

Amorphous SnO decorated ZnSn(OH) promotes interfacial hydroxyl polarization for deep photocatalytic toluene mineralization.

Surface hydroxyl groups play a decisive role in the generation of hydroxyl radicals with stronger oxidizing ability, which is indispensable in photocatalytic VOCs removal, especially under the condition of low humidity. In this work, non-noble amorphous SnO decorated ZnSn(OH) (ZSH) was synthesized by an in-situ method. The charge transport, reactant activation and hydroxyl polarization are enhanced through decoration of amorphous SnO on ZSH.

Dual-quantum-dots heterostructure with confined active interface for promoted photocatalytic NO abatement.

Constructing heterostructure is an effective way to fabricate advanced photocatalysts. However, the catalytic performance of typical common multi-dimensional bulk heterostructure still suffers from the limited active interface and inefficient carrier migration. Herein, we successfully synthesize the SnO/CsBiI dual-quantum-dots nanoheterostructure (labeled as SCX, X = 1, 2, 3) for efficiently and stably photocatalytic NO removal under visible light irradiation.

Chemical Discrimination of Benzene Series and Molecular Recognition of the Sensing Process over Ti-Doped CoO.

This work achieved the chemical discrimination of benzene series (toluene, xylene isomers, and ethylbenzene gases) based on the Ti-doped CoO sensor. Benzene series gases presented different gas-response features due to the differences in redox rate on the surface of the Ti-doped CoO sensor, which created an opportunity to discriminate benzene series via the algorithm analysis. Excellent groupings were obtained via the principal component analysis.

Identification of deactivation-resistant origin of In(OH) for efficient and durable photodegradation of benzene, toluene and their mixtures.

Aromatic hydrocarbon is a representative type of VOCs, which causes adverse effects to human health. The degradation stability of aromatic hydrocarbon is of vital importance to commercializing a photocatalyst for its practical application. The most commonly used titanium dioxide photocatalyst (P25) was deactivated rapidly in the photocatalytic VOCs degradation process.

Crystal-structure dependent reaction pathways in photocatalytic formaldehyde mineralization on BiPO.

Formaldehyde as significant environmental hazard in air seriously harm the environment and human health. Although photocatalysis has demonstrated the possibility for HCHO degradation, it has long been limited by unsatisfied degradation efficiency and the unclear reaction mechanism. Here, we confirm that surface atomic arrangement of BiPO plays a critical role in photooxidation of HCHO via modulating the reaction pathway, offering 2.

Surface Lattice Oxygen Activation on SrSbO Enhances the Photocatalytic Mineralization of Toluene: from Reactant Activation, Intermediate Conversion to Product Desorption.

Transition-metal oxide photocatalysis has attracted increasing attention in environmental remediation and solar energy conversion. Surface lattice oxygen is the key active site on the metal oxide, but its role and activation mechanism in the photocatalytic VOC mineralization are still unclear. In this work, we have demonstrated that SrSbO exhibits an excellent photocatalytic activity and stability compared to TiO (P25) in gaseous toluene mineralization because the lattice oxygen on SrSbO can be activated efficiently.

Rare-Earth Single-Atom La-N Charge-Transfer Bridge on Carbon Nitride for Highly Efficient and Selective Photocatalytic CO Reduction.

Photocatalytic CO conversion into valuable solar fuels is highly appealing, but lack of directional charge-transfer channel and insufficient active sites resulted in limited CO reduction efficiency and selectivity for most photocatalytic systems. Herein, we designed and fabricated rare-earth La single-atoms on carbon nitride with La-N charge-transfer bridge as the active center for photocatalytic CO reaction. The formation of La single-atoms was certified by spherical aberration-corrected HAADF-STEM, STEM-EELS, EXAFS, and theoretical calculations.

Nature-inspired CaCO loading TiO composites for efficient and durable photocatalytic mineralization of gaseous toluene.

The accumulation of intermediates or final products on TiO during photocatalytic volatile organic compounds (VOCs) degradation is typically neglected, despite the fact that it could result in the block of active sites and the deactivation of photocatalysts. Inspired from the natural formation of stalactite (CaCO + HO + CO ↔ Ca(HCO)), we fabricated CaCO loading TiO composites (CCT21) to realize the spontaneously transfer of accumulated final products (CO and HO). Efficient and durable performance for gaseous toluene removal has been demonstrated and the cost of photocatalyst is greatly reduced by the comparison of specific activity.

Identification of Halogen-Associated Active Sites on Bismuth-Based Perovskite Quantum Dots for Efficient and Selective CO-to-CO Photoreduction.

All-inorganic Pb-free bismuth (Bi) halogen perovskite quantum dots (PQDs) with distinct structural and photoelectric properties provide plenty of room for selective photoreduction of CO. However, the efficient conversion of CO-to-CO with high selectivity on Bi-based PQDs driven by solar light remains unachieved, and the precise reaction path/mechanism promoted by the surface halogen-associated active sites is still poorly understood. Herein, we screen a series of nontoxic and stable CsBiX (X = Cl, Br, I) PQDs for selective photocatalytic reduction of CO-to-CO at the gas-solid interface.

Capsaicin attenuates liver fibrosis by targeting Notch signaling to inhibit TNF-α secretion from M1 macrophages.

Background: Capsaicin is a chili pepper extract with multiple therapeutic properties including anti-liver fibrosis. However, the paucity of its underlying mechanisms limited its widely clinical application.

Methods: In the present study, carbon tetrachloride (CCl) was used to induce liver fibrosis in mice, and transforming growth factorβ1 (TGFβ1) was used to mimic liver fibrosis .

La-doping induced localized excess electrons on (BiO)CO for efficient photocatalytic NO removal and toxic intermediates suppression.

Photocatalysis technology has been extensively adopted to abate typical air pollutants. Nevertheless, it is a challenge to develop photocatalysts aiming to simultaneously improve photocatalytic selectivity and efficiency. In this study, to improve the photocatalytic selectivity and the performance of (BiO)CO in the oxidation of NO to target products (NO /NO), we developed a novel method to construct La-doped (BiO)CO (La-BOC) for forming localized excess electrons (Ex) on (BiO)CO surface.

Synergistic effects of crystal structure and oxygen vacancy on BiO polymorphs: intermediates activation, photocatalytic reaction efficiency, and conversion pathway.

This work unraveled the synergistic effects of crystal structure and oxygen vacancy on the photocatalytic activity of BiO polymorphs at an atomic level for the first time. The artificial oxygen vacancy is introduced into α-BiO and β-BiO via a facile method to engineer the band structures and transportation of carriers and redox reaction for highly enhanced photocatalysis. After the optimization, the photocatalytic NO removal ratio on defective β-BiO was increased from 25.

Theoretical design and experimental investigation on highly selective Pd particles decorated CN for safe photocatalytic NO purification.

Rational design of highly active and selective photocatalyst for NO removal is significant for the commercial application of photocatalytic technology because the secondary byproduct caused by insufficient and non-selective pollutant oxidation process is a major challenge. In this work, Pd nanoparticles decorated CN (PdCN) is designed by density functional theory (DFT) at first. The PdCN exhibits superiority to CN in terms of both kinetics and thermodynamics performances, as reflected in the lower activation barrier of rate-determining step and higher selectivity for the final product (nitrate) instead of toxic intermediate (NO).

The Association of Autoantibodies in Hyperthyroid Heart Disease Combined with Pulmonary Hypertension.

Hyperthyroidism is a clinical state that results from increased thyroid hormone levels which has a significant impact on cardiac function and structure. Graves' disease is the most common cause of hyperthyroidism in iodine-replete areas. Hyperthyroid heart disease may be associated with pulmonary hypertension in patients who have overt hyperthyroidism.