Purpose: Many cancer patients express interest in using herbal medicine during chemotherapy, but little is known about its benefits and risks. This study aimed to evaluate the effects of the Chinese herbal medicine JianPi-BuShen formula (JPBS) on adjuvant chemotherapy completion in colon cancer patients.
Patients And Methods: This multi-center, phase III, randomized, placebo-controlled trial included patients with stage II (high risk for recurrence) and stage III colon cancer following surgery, planning to receive CAPOX (capecitabine and oxaliplatin) chemotherapy.
Objectives: () is a globally prevalent bacterium that increases the risk of developing various gastrointestinal diseases, including gastric adenocarcinoma. This study aimed to evaluate the performances of real-time PCR assay in detecting infection, as well as clarithromycin and levofloxacin resistance, in both stool and gastric biopsy specimens.
Methods: Stool and gastric biopsy specimens were collected from patients within one to three days post-hospitalization.
Background And Objectives: The success rate of () eradication in China is declining. The aim of this study was to evaluate eradication outcomes in clinical practice and identifies factors contributing to treatment failure.
Methods: A retrospective review was conducted on patients treated for infection with 14-day bismuth-containing quadruple therapy at a Beijing medical center from January 2020 to December 2023.
Aim: To investigate the impact of triglyceride on hypertriglyceridemic acute pancreatitis (HTG-AP) and different lipid-lowering methods on triglyceride-lowering efficiency and HTG-AP.
Methods: The patients with HTG-AP from January 2012 to December 2023 in Civil Aviation General Hospital were analyzed, retrospectively. Patients were divided and compared according to whether their triglycerides were below 5.
The 210 Pb burden in the skeleton is a measurement value suitable for the estimation of the cumulative exposure to radon, based on which the resultant risk of lung cancer can be derived. There have been a handful of studies that successfully measured 210 Pb activity in the bones of volunteers who had chronic exposure to high concentrations of radon occupationally or in their residences. However, the quantitative relationship between measured 210 Pb activity and radon exposure remains elusive.
View Article and Find Full Text PDFDirect seeding ratoon rice (DSRR) system is a planting method that can significantly increase grain yield, improving light and temperature utilization efficiency and reducing labor input. However, the current nitrogen fertilizer management method which does not aim at the seedling emergence and development characteristics of DSRR just is only based on the traditional method of transplanting ratoon rice, and which is not conducive to the population development and yield improvement. To determine the suitable nitrogen fertilizer application optimization, we set four nitrogen fertilizer application treatments (N0, no nitrogen fertilizer; N1, traditional nitrogen fertilizer; N2, transferring 20% of total nitrogen from basal fertilizer to tillering stage; N3, reducing total nitrogen by 10% from N2 tillering fertilizer) on a hybrid rice "Fengliangyouxiang1 (FLYX1)" and an inbred rice "Huanghuazhan (HHZ)" under DSRR.
View Article and Find Full Text PDFBackground: SPL transcription factors play vital roles in regulating plant growth, development, and abiotic stress responses. Sugar beet (Beta vulgaris L.), one of the world's main sugar-producing crops, is a major source of edible and industrial sugars for humans.
View Article and Find Full Text PDFBackground: Radiation proctitis is a common complication that occurs as a result of radiation therapy used to treat pelvic malignancies. The most common and bothersome symptom resulting from radiation proctitis is rectal bleeding, which can be persistent or recurrent. This study aimed to review our experience and evaluate the efficacy and safety of transcolonoscopic spraying of formalin solution in patients with hemorrhagic radiation proctitis.
View Article and Find Full Text PDFThe counting efficiency calibration for in vivo measurement is crucial to derive the activity of radionuclides residing inside a monitored subject. Recently, virtual calibration based on computational phantoms has become popular, yet some key questions remain unresolved. Here, we focus on the in vivo measurement of Pb-210 in the skull and systematically examine how virtual calibration compares to those using physical phantoms and how the variety of computational phantoms affects the derived counting efficiency.
View Article and Find Full Text PDFRutin, a flavonoid rich in buckwheat, is important for human health and plant resistance to external stresses. The hydrolysis of rutin to quercetin underlies the bitter taste of Tartary buckwheat. In order to identify rutin hydrolysis genes, a 200 genotypes mini-core Tartary buckwheat germplasm resource was re-sequenced with 30-fold coverage depth.
View Article and Find Full Text PDFUntil now, there have been no randomized controlled trials directly evaluating the efficacy of high-dose ilaprazole-amoxicillin dual therapy (HT) in comparison to other standard treatments for () infection. This study aimed to compare the effectiveness and safety of HT with bismuth quadruple therapy (BQT) as an initial treatment for . This single-center, prospective, randomized clinical controlled trial recruited 225 consecutive patients.
View Article and Find Full Text PDFThe GATA family of transcription factors is zinc finger DNA binding proteins involved in a variety of biological processes, including plant growth and development and response to biotic/abiotic stresses, and thus play an essential role in plant response to environmental changes. However, the gene family of () has not been systematically analyzed and reported yet. Herein, we used a variety of bioinformatics methods and quantitative Real-Time Polymerase Chain Reaction (qRT-PCR) to explore the evolution and function of the 33 genes identified.
View Article and Find Full Text PDFThe second-largest transcription factor superfamily in plants is that of the basic helix-loop-helix (bHLH) family, which plays an important complex physiological role in plant growth, tissue development, and environmental adaptation. Systematic research on the bHLH family will enable a better understanding of this species. Herein, authors used a variety of bioinformatics methods and quantitative Real-Time Polymerase Chain Reaction (qRT-PCR) to explore the evolution and function of the 218 genes identified.
View Article and Find Full Text PDFObjective: This study aims to investigate the therapeutic effects of combining pseudomonas aeruginosa injection (PAI) with endostar on patients with malignant pleural effusion and ascites.
Methods: In this prospective study, a total of 105 patients with malignant pleural effusion and ascites admitted to our hospital from January 2019 to April 2022 were selected as research subjects. Among them, 35 patients treated with PAI combined with endostar were enrolled in the observation group, while 35 patients treated with PAI and another 35 patients treated with endostar were enrolled in the control groups.
Rhizoctonia solani is a devastating soil-borne pathogen that seriously threatens the cultivation of economically important crops. Multiple strains with a very broad host range have been identified, but only 1 (AG1-IA, which causes rice sheath blight disease) has been examined in detail. Here, we analyzed AG4-HGI 3 originally isolated from Tartary buckwheat (Fagopyrum tataricum), but with a host range comparable to AG1-IA.
View Article and Find Full Text PDFThe Mg(p, γ)Al reaction plays an important role in the study of cosmic 1.809 MeV γ-ray as a signature of ongoing nucleosynthesis in the Galaxy. At astrophysical temperature around 0.
View Article and Find Full Text PDFThis study explored the feasibility of treating wastewater using sulfur-driven autotrophic denitrification (SAD) coupled with the bio-cathode of microbial fuel cell (MFC), focusing on simultaneous bioelectricity generation, denitrification, and desulphurization. A maximum output voltage of 360 mV was obtained with a power generation cycle of 25 h when simulated wastewater with 100.0 mg/L of each NO-N and S-S was employed as the influent in the SAD-BMFC.
View Article and Find Full Text PDFGATA is a transcription factor that exerts a vital function in plant growth and development, physiological metabolism, and environmental responses. However, the gene family has rarely been studied in Tartary buckwheat since the completion of its genome. This study used bioinformatics methods to identify genes of Tartary buckwheat and to analyze their subfamily classification, structural composition, and developmental evolution, as well as to discuss the expression patterns of genes in different subfamilies.
View Article and Find Full Text PDFProposed mechanisms for the production of calcium in the first stars (population III stars)-primordial stars that formed out of the matter of the Big Bang-are at odds with observations. Advanced nuclear burning and supernovae were thought to be the dominant source of the calcium production seen in all stars. Here we suggest a qualitatively different path to calcium production through breakout from the 'warm' carbon-nitrogen-oxygen (CNO) cycle through a direct experimental measurement of the F(p, γ)Ne breakout reaction down to a very low energy point of 186 kiloelectronvolts, reporting a key resonance at 225 kiloelectronvolts.
View Article and Find Full Text PDFWe aimed to elucidate the physiological and biochemical mechanism by which exogenous hydrogen peroxide (HO) alleviates salt stress toxicity in Tartary buckwheat ( (L.) Gaertn). Tartary buckwheat "Chuanqiao-2" under 150 mmol·L salt (NaCl) stress was treated with 5 or 10 mmol·L HO, and seedling growth, physiology and biochemistry, and related gene expression were studied.
View Article and Find Full Text PDFBackground: Transcription factors (TFs) play important roles in plants. Among the major TFs, GATA plays a crucial role in plant development, growth, and stress responses. However, there have been few studies on the GATA gene family in foxtail millet (Setaria italica).
View Article and Find Full Text PDFfungi (AMF) are a class of beneficial microorganisms that are widely distributed in soil ecosystems and can form symbionts with 80% of terrestrial higher plants, and improve the nutritional status of plants. The use of AMF as a biocontrol method to antagonize soil-borne pathogens has received increasing interest from phytopathologists and ecologists. In this paper, the mechanisms of resistance to diseases induced by AMF and the application of AMF to plant fungal, bacterial, and nematode diseases have been summarized.
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