RNA-binding protein promotes the tumor progression of gastric cancer by binding to and regulating gastric cancer-related genes.

Background: This study sought to identify the downstream target genes of enolase 1 (), clarify the role of in gastric cancer (GC), and provide novel insights into the regulatory mechanisms of in the occurrence and development of GC.

Methods: We performed RNA-immunoprecipitation sequencing in MKN-45 cells to study the types and abundance of pre-messenger RNA (mRNA)/mRNA bound by , the binding sites and motifs, the relationship between binding and its regulation of transcription level, and alternative splicing level by combining with RNA-sequencing (RNA-seq) data to further clarify the role of in GC.

Results: We found that stabilized the expression of SRY-box transcription factor 9 (), vascular endothelial growth factor A (), G protein-coupled receptor class C group 5 member A (), and myeloid cell leukemia-1 () by binding to their mRNA, which increased the growth of GC.

Insulin for hyperglycemia prevention and management during postgastrectomy nutrition support in gastric cancer: Reduced complications in a retrospective cohort study in China.

Background And Objectives: To evaluate the effectiveness of insulin addition to the total nutrition admixture (TNA) for glycemic control among patients with gastric cancer (GC) receiving supplementary parenteral nutrition (SPN) after gastrectomy.

Methods And Study Design: A retrospective cohort study was conducted among 208 noncritical ill patients who underwent gastrectomy for GC from 2017 to 2019 at a tertiary teaching hospital in Lanzhou, China. All the included patients received individualized SPN and enteral nutrition treatment after gastrectomy.

Review on Micro-Alloying and Preparation Method of 7xxx Series Aluminum Alloys: Progresses and Prospects.

Notably, 7xxx series aluminum alloy has become the most popular nonferrous alloy, extensively used in industry, construction and transportation trades, due to its high comprehensive properties such as high static strength, high strength, heat resistance, high toughness, damage resistance, low density, low quenching sensitivity and rich resource. The biggest challenge for aluminum alloy today is to greatly improve the corrosion resistance of the alloy, while maintaining its strength. The preparation method of 7xxx series aluminum alloy requires controlling time lapses in the process of heating, holding and cooling, and there are many species precipitates in the crystal, but the precipitated strengthening phase is a single type of equilibrium η' phase.

The Mediterranean diet and gastrointestinal cancers risk.

It is known that the Mediterranean diet (MD), which is characterized by high consumption of vegetables, fruits, cereals, beans, nuts, and olive oil, moderate consumption of fish, white meat, eggs, dairy products, and alcohol, and low consumption of red meat, processed meats, and foods rich in sugars or fats, can reduce the risk of cardiovascular diseases, type 2 diabetes, neurodegenerative diseases, and cancers. Previous epidemiologic studies had confirmed the protective role in the incidence and mortality of gastrointestinal cancers. This review discusses MD and gastrointestinal cancers risk through the studies which examined esophageal cancer, gastric cancer, pancreatic cancer, or colorectal cancer.

CD4(+)CD25 (+) regulatory T cells are not required for mesenchymal stem cell function in fully MHC-mismatched mouse cardiac transplantation.

Although the immunomodulative properties of mesenchymal stem cells (MSCs) open up attractive possibilities in solid-organ transplantation, information concerning the optimal dose, route, timing of administration, major histocompatibility complex (MHC)-restriction and relevant mechanisms is currently lacking. Therefore, better characterization of MSC immunoregulatory activity and elucidation of its mechanisms are crucial. In this study, we confirmed that MSCs did not elicit proliferation by allogeneic CD4(+) T cells, suggesting that MSCs were not immunogenic.

De Garengeot hernia: the ultrasound and computed tomographic findings in an 81-year-old woman.

The presence of appendix within a femoral hernia is a rare condition in an incarcerated femoral hernia. It has a characteristic groin mass, and the diagnosis of appendicitis is mainly made intraoperatively. A specific imaging appearance (ultrasonography, computed tomography [CT]) allows accurate prospective diagnosis.