Dendrite-free Zn anode induced by Sn/NC towards highly efficient Zn-ion batteries.

Herein, Sn nanoparticles supported on N-doped carbon (Sn/NC) were constructed by a g-CN assisted strategy for the interface layer of Zn anodes in Zn-ion batteries. The presence of Sn/NC effectively regulates the zinc plating/stripping process, which makes Sn/NC@Zn outstanding in both symmetrical and full cells.

Structural Regulating of Cu-Based Metallic Electrocatalysts for CO to C Products Conversion.

Electrochemical carbon dioxide reduction reaction (CORR) to highly value-added multi-carbon (C) fuels or chemicals is a promising pathway to address environment issues and energy crisis. In the periodic table, Cu as only the candidate can convert CO to C products such as CH and CHOH due to the suitable absorption energy to reaction intermediate. However, application of Cu is limited for its low activity and poor selectivity.

Convergence of Tandem Catalysis and Nanoconfinement Promotes Electroreduction of CO to C Products.

An efficient electrocatalytic conversion of CO into valuable multicarbon (C) products requires enhanced C-C coupling of C1 intermediates. Herein, we combine a tandem effect with a confinement strategy to construct a hollow CuO@Ag nanoshell electrocatalyst with a well-defined porous structure to improve the *CO intermediate coverage on the catalyst surface. In CO electroreduction, in situ Raman spectroscopy shows that the introduction of Ag can not only promote the CO intermediate production but also improve the stability of Cu to capture the *CO intermediate due to a CO-tandem effect, and the fine-tuned hollowness degree and pore size of CuO@Ag create a spatially confined microenvironment for trapping CO as well as the enrichment of CO, which greatly facilitate subsequent C-C coupling for C product.

Modulation of copper sites in porphyrin metal-organic frameworks for electrochemical ascorbic acid sensing.

Two metal-organic frameworks (MOFs) with different Cu-centered coordination structures were synthesized. By introducing 4,4-bipyridine as a linker in the Cu-MOFs, we have discovered that Cu-O, instead of Cu-N, is the active site with higher electrocatalytical activity towards ascorbic acid, which is essential to understand and develop Cu-based ascorbic acid sensors.

PDLIM3 knockdown promotes ferroptosis in endometriosis progression via inducing Gli1 degradation and blocking Hedgehog signaling pathway.

Aims: Current evidence suggests that there is no completely effective method for endometriosis (EMS) without trauma due to diverse adverse effects. Reliable evidence illustrates that inhibiting ferroptosis is a potential strategy for EMS. We sufficiently verified that the expression of endogenous protein PDZ and LIM domain 3 (PDLIM3) was significantly increased in EMS.

Plasmon-Switched Kinetics for Formic Acid Dehydrogenation: Selective Adsorption Driven by Local Field and Hot Carriers.

Understanding illumination-mediated kinetics is essential for catalyst design in plasmon catalysis. Here we prepare Pd-based plasmonic catalysts with tunable electronic structures to reveal the underlying illumination-enhanced kinetic mechanisms for formic acid (HCOOH) dehydrogenation. We demonstrate a kinetic switch from a competitive Langmuir-Hinshelwood adsorption mode in dark to a non-competitive type under irradiation triggered by local field and hot carriers.

Photo-enhanced dehydrogenation of formic acid on Pd-based hybrid plasmonic nanostructures.

Coupling visible light with Pd-based hybrid plasmonic nanostructures has effectively enhanced formic acid (FA) dehydrogenation at room temperature. Unlike conventional heating to achieve higher product yield, the plasmonic effect supplies a unique surface environment through the local electromagnetic field and hot charge carriers, avoiding unfavorable energy consumption and attenuated selectivity. In this minireview, we summarized the latest advances in plasmon-enhanced FA dehydrogenation, including geometry/size-dependent dehydrogenation activities, and further catalytic enhancement by coupling local surface plasmon resonance (LSPR) with Fermi level engineering or alloying effect.

Natural oxidase-mimicking copper-organic frameworks for targeted identification of ascorbate in sensitive sweat sensing.

Sweat sensors play a significant role in personalized healthcare by dynamically monitoring biochemical markers to detect individual physiological status. The specific response to the target biomolecules usually depends on natural oxidase, but it is susceptible to external interference. In this work, we report tryptophan- and histidine-treated copper metal-organic frameworks (Cu-MOFs).

Destruction of a Copper Metal-Organic Framework to Induce CuPt Growth as a Heterojunction Catalyst for Hydrogen Peroxide Sensing.

Assembling bimetallic alloys (BAs) with metal-organic frameworks (MOFs) to form heterojunctions has emerged as a promising strategy for the construction of highly active electrocatalysts. However, the current approaches to prepare BA@MOF heterojunctions suffer from poor controllability. In this work, a fascinating method involving partial thermal reduction and galvanic replacement to induce CuPt growth on a CuHHTP MOF (HHTP=2,3,6,7,10,11-hexahydroxytriphenylene) is reported in order to construct a CuPt@CuHHTP heterojunction.

Synergistic Combination of Fermi Level Equilibrium and Plasmonic Effect for Formic Acid Dehydrogenation.

Developing an efficient catalyst for formic acid (FA) dehydrogenation is a promising strategy for safe hydrogen storage and transportation. Herein, we successfully developed trimetallic NiAuPd heterogeneous catalysts through a galvanic replacement reaction and a subsequent chemical reduction process to boost hydrogen generation from FA decomposition at room temperature by coupling Fermi level engineering with plasmonic effect. We demonstrated that Ni worked as an electron reservoir to donate electrons to Au and Pd driven by Fermi level equilibrium whereas plasmonic Au served as an optical absorber to generate energetic hot electrons and a charge-redistribution mediator.

In situ electrochemical reductive construction of metal oxide/metal-organic framework heterojunction nanoarrays for hydrogen peroxide sensing.

Transition metal oxide/metal-organic framework heterojunctions (TMO@MOF) that combine the large specific surface area of MOFs with TMOs' high catalytic activity and multifunctionality, show excellent performances in various catalytic reactions. Nevertheless, the present preparation approaches of TMO@MOF heterojunctions are too complex to control, stimulating interests in developing simple and highly controllable methods for preparing such heterojunction. In this study, we propose an in situ electrochemical reduction approach to fabricating CuO nanoparticle (NP)@CuHHTP heterojunction nanoarrays with a graphene-like conductive MOF CuHHTP (HHTP is 2,3,6,7,10,11-hexahydroxytriphenylene).

downregulation in lung adenocarcinoma: a potential therapeutic target associated with immune infiltration.

Background: The current study aimed to investigate the interrelation between and the prognosis of patients suffering from lung adenocarcinoma (LUAD) following surgery.

Methods: The differentially expressed gene (DEG) was screened by the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and Immunology Database and Analysis Portal (ImmPort) databases. The relationship between and clinical data of LUAD was analyzed in TCGA and Kaplan-Meier (KM)-plotter databases.

Reshaping Membrane Polymorphism of Polymer Vesicles through Dynamic Gas Exchange.

The quest for a universal method to shape the vesicular morphology in dynamic and diversified manners is a challenging topic of cell mimicry. Here we present a simple gas exchange strategy that can direct the deformation movements of polymer vesicles. Such vesicles are assembled by a class of gas-based dynamic polymers, where CO connects between the frustrated Lewis pair via dynamic gas-bridged bonds.

Targeting -Regulatory Elements for Rice Grain Quality Improvement.

Rice is the most important source of food worldwide, providing energy, and nutrition for more than half of the population worldwide. Rice grain quality is a complex trait that is affected by several factors, such as the genotype and environment, and is a major target for rice breeders. -regulatory elements (CREs) are the regions of non-coding DNA, which play a critical role in gene expression regulation.

Outcomes and safety of concomitant topiramate or metformin for antipsychotics-induced obesity: a randomized-controlled trial.

Background: Although there are some existing data describing the usage of topiramate in patients with antipsychotic-induced obesity, study on its comparison with metformin is limited. This study aimed to explore the effectiveness and safety of concomitant topiramate on antipsychotic-induced obesity as well as its comparison with metformin.

Methods: 62 stabilized outpatients with antipsychotic-induced obesity were randomized into the topiramate group and the metformin group with 16-week treatment.

Structural variation of transition metal-organic frameworks using deep eutectic solvents with different hydrogen bond donors.

Deep eutectic solvents (DESs) have attracted extensive attention in the field of material synthesis as green solvents. They have similar physical and chemical properties to the traditional ionic liquids (ILs) while being much cheaper and more environmentally friendly. Herein, seven transition metal-organic frameworks, namely [NH][Zn(BTC)(NH)]·HO (1), [Cu(PDC)(NH)] (2), [Co(HBTC)(e-urea)]·(e-urea)·1/4HO (3), K(NH)[Mn(PZDC)] (4), [NH][Mn(BTC)(HO)] (5), [CHNH][Mn(HBTC)(BTC)·3HO (6), and [Co(BTC)(urea)]·2HO (7), were synthesized in deep eutectic solvents of choline chloride and urea/e-urea/m-urea (HBTC = 1,3,5-benzenetricarboxylic acid; HPDC = 2,6-pyridinedicarboxylic acid; HPZDC = 3,5-pyrazoledicarboxylic acid; e-urea = ethylene urea; m-urea = N,N-dimethylurea).

The efficacy, acceptability, and safety of five atypical antipsychotics in patients with first-episode drug-naïve schizophrenia: a randomized comparative trial.

Background: Differences in effectiveness and tolerability between different atypical antipsychotics may affect schizophrenic patients' treatment adherence or prognosis. However, which kind of antipsychotic was more effective and safe in the treatment of schizophrenia is still being debated. This study attempted to understand whether there are any differences in efficacy, acceptability, and safety between the five atypical antipsychotics in patients with first-episode schizophrenia.

Initiation of Targeted Nanodrug Delivery in Vivo by a Multifunctional Magnetic Implant.

Implant-mediated targeted drug delivery without an external magnetic field is very challenging. In this work, we report targeted nanodrug delivery initiated by a FeO/poly(lactic-co-glycolic acid) implant scaffold with high magnetism. The implant scaffold is biocompatible and durable.