Synopsis of recent research by authors named "Jianming Fang"
- Jianming Fang's research primarily focuses on the interplay between genetics, immunology, and cancer treatment, particularly gastrointestinal cancers such as gastric and gallbladder cancer, exploring novel therapeutic strategies to improve patient outcomes through immunomodulation and genetic assessments.
- Recent findings indicate that the gut microbiota, specifically Akkermansia muciniphila (AKK), can influence the immune microenvironment in gastric cancer, promoting cell apoptosis and enhancing the immune response by favoring M1 macrophage polarization and cytokine expression relevant to cytotoxic T-lymphocytes.
- Fang's work also emphasizes the clinical implications of gene polymorphisms in GSTM1 and GSTT1 concerning gallbladder carcinoma, alongside strategies in managing hepatocellular carcinoma with cirrhosis that focus on minimizing surgical risks and complications related to bleeding.
