Publications by authors named "Jianling Mai"
Article Synopsis
- Chronic kidney disease (CKD) is a serious health problem that affects many people, and there aren't many good treatments for it.
- A study tested a substance called emodin, which comes from rhubarb, to see if it can help stop the harmful scarring (fibrosis) in kidneys caused by CKD.
- The results showed that emodin helped improve kidney health in lab rats and reduced signs of fibrosis, suggesting it could be a helpful treatment for CKD.
Background: The 2017 Oxford classification of immunoglobulin A nephropathy (IgAN) recently reported that crescents could predict a worse renal outcome. Early prediction of crescent formation can help physicians determine the appropriate intervention, and thus, improve the outcomes. Therefore, we aimed to establish a nomogram model for the prediction of crescent formation in IgA nephropathy patients.
View Article and Find Full Text PDFPurpose: This study aimed to develop two predictive nomograms for the assessment of long-term survival status in hemodialysis (HD) patients by examining the prognostic factors for all-cause mortality and cardiovascular (CVD) event mortality.
Patients And Methods: A total of 551 HD patients with an average age of over 60 were included in this study. The patients' medical records were collected from our hospital and randomly allocated to two cohorts: the training cohort (n=385) and the validation cohort (n=166).
Introduction: A working group on the Oxford classification of IgA nephropathy (IgAN) recently reported that crescents detected in the kidney tissue predicted a worse renal outcome. However, the effect of C1 lesion (crescents in <1/4th of all glomeruli) and their volume on the prognosis of IgAN is still unclear. We explored the association of C1 lesion with the renal prognosis in IgAN patients without obvious chronic renal lesions (glomerulosclerosis <25%, T score <2).
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