Rationale and design of a comparison of angiography-derived fractional flow reserve-guided and intravascular ultrasound-guided intervention strategy for clinical outcomes in patients with coronary artery disease: a randomised controlled trial (FLAVOUR II).

Introduction: Percutaneous coronary intervention (PCI) guided by coronary angiography-derived fractional flow reserve (FFR) or intravascular ultrasound (IVUS) has shown improved clinical outcomes compared with angiography-only-guided PCI. In patients with intermediate stenoses, FFR resulted in fewer coronary interventions and was non-inferior to IVUS with respect to clinical outcomes. However, whether this finding can be applied to angiography-derived FFR in significant coronary artery disease (CAD) remains unclear.

Role of cardiac endothelial cells-derived microRNAs in cardiac remodeling.

Cardiac remodeling refers to a series of compensatory changes in the size, shape, and function of the myocardium in response to heart injury. This process involves the permanent multiple cell types of the myocardium such as cardiomyocytes (CMs), cardiac fibroblasts (CFs), endothelial cells (ECs), and inflammatory cells. Dynamic communications among different cells, particularly the communication between ECs and CMs and between ECs and CFs, play an important role in cardiac remodeling.

Takotsubo cardiomyopathy and giant r wave syndrome mimicking acute myocardial infarction: A case report.

Rationale: The clinical features of Takotsubo cardiomyopathy largely overlap with those of acute myocardial infarction, especially in the presence of ST-segment elevation on the initial electrocardiogram. Giant R wave syndrome has mainly been observed in the hyperacute phase of acute myocardial infarction.

Patient Concerns: In this study, we report a unique case of Takotsubo cardiomyopathy that caused giant R wave syndrome.

CaLRS: a critical-aware shared LLC request scheduling algorithm on GPGPU.

Ultra high thread-level parallelism in modern GPUs usually introduces numerous memory requests simultaneously. So there are always plenty of memory requests waiting at each bank of the shared LLC (L2 in this paper) and global memory. For global memory, various schedulers have already been developed to adjust the request sequence.