AVL-armed oncolytic vaccinia virus promotes viral replication and boosts antitumor immunity via increasing ROS levels in pancreatic cancer.

Pancreatic malignant neoplasm is an extremely deadly malignancy well known for its resistance to traditional therapeutic approaches. Enhanced treatments are imperative for individuals diagnosed with pancreatic cancer (PC). Recent investigations have shed light on the wide-ranging anticancer properties of genetic therapy facilitated by oncolytic vaccinia virus.

Oncolytic vaccinia virus harboring aphrocallistes vastus lectin exerts anti-tumor effects by directly oncolysis and inducing immune response through enhancing ROS in human ovarian cancer.

Aphrocallistes vastus lectin (AVL) is a Ca dependent C-type lectin produced by sponges. Previous studies have demonstrated that oncolytic vaccinia virus harboring AVL (oncoVV-AVL) effectively triggers cell death in various tumors. However, the effects of oncoVV-AVL on human ovarian cancer (OV) remain unknown.

Residue behaviors and dietary risk assessment of dinotefuran and its metabolites in Oryza sativa by a new HPLC-MS/MS method.

In this study, we developed a new method to detect dinotefuran and its metabolites (UF and DN) in Oryza sativa (Rice) by HPLC-MS/MS in multiple reaction monitoring (MRM) modes. The recovery rates for dinotefuran, UF and DN were 82.3-85.

Dissipation and Residues of Dichlorprop-P and Bentazone in Wheat-Field Ecosystem.

Dichlorprop-P and bentazone have been widely used in the prevention and control of weeds in wheat field ecosystems. There is a concern that pesticide residues and metabolites remain on or in the wheat. Thus, the study of the determination and monitoring of their residues in wheat has important significance.

Dissipation kinetics and residue of LH-2010A in cucumber and soil under greenhouse condition.

LH-2010A is a newly developed fungicide with novel mode of action in the treatment of cucurbit downy mildew. Dissipation kinetics and residue levels of LH-2010A in cucumber were investigated using a QuEChERS method with GC-ECD. Field trials were constructed at three different sites in China in 2013 and 2014.