Status and Development of Nuclear Medicine Over One Decade in Beijing.

 Our objective was to investigate the basic information of the personnel and facilities of nuclear medicine in Beijing.  This survey was performed by the Beijing Quality Control Center in 2018. The investigation included personnel, equipment, and clinical applications, and data were then compared with previous surveys.

Skeletal standardized uptake values obtained using quantitative SPECT/CT for the detection of bone metastases in patients with lung adenocarcinoma.

Purpose: To assess the utility of skeletal standardized uptake values (SUVs) obtained using quantitative single-photon emission computed tomography/computed tomography (SPECT/CT) in differentiating bone metastases from benign lesions, particularly in patients with lung adenocarcinoma.

Methods: Patients with lung adenocarcinoma who had undergone whole-body Tc-99m methyl-diphosphonate (Tc-MDP) bone scans and received late phase SPECT/CT were retrospectively analyzed in this study. The maximum SUV (SUVmax); Hounsfield units (HUs); and volumes of osteoblastic, osteolytic, mixed, CT-negative metastatic and benign bone lesions, and normal vertebrae were compared.

Revisiting sea-level budget by considering all potential impact factors for global mean sea-level change estimation.

Accurate estimates of global sea-level change from the observations of Altimetry, Argo and Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow-on (GRACE-FO) are of great value for investigating the global sea-level budget. In this study, we analyzed the global sea-level change over the period from January 2005 to December 2019 by considering all potential impact factors, i.e.

A Formula to Calculate the Threshold for Radiotherapy Targets on PET Images: Simulation Study.

Background: Positron emission tomography (PET) images are being applied for defining radiotherapy targets. However, a recognized method for defining radiotherapy targets is lacking. We investigate the threshold to outline the radiotherapy target of a tumor on PET images and its influencing factors, and then expressed it by formula.

Effective Attributes Quantification to Bridge Gap between Elastic Properties and Reservoir Parameters in Self-Resource Rocks.

The successful production of unconventional resources such as shale gas is highly dependent on its two reservoir properties, organic matter and rock brittleness. High resolution spatially characterization of these two unconventional reservoir properties needs surface reflection seismic data. However, to delineate these two parameters on seismic scale is a challenging task because poor correlation is observed between these parameters and elastic properties of the rock.

Association of the Cumulative Dose of Radioactive Iodine Therapy With Overall Survival in Patients With Differentiated Thyroid Cancer and Pulmonary Metastases.

The optimal cumulative dose of radioactive iodine therapy (RAIT) for patients with differentiated thyroid cancer (DTC) and pulmonary metastases (PM) is not known, therefore we evaluated the association between the cumulative dose of RAIT and overall survival (OS). A total of 202 patients with DTC and PM who underwent thyroidectomy and RAIT were analyzed in this study. The median cumulative dose of RAIT was 530 mCi.

Measurement and Evaluation of Quantitative Performance of PET/CT Images before a Multicenter Clinical Trial.

To ensure the reliability of the planned multi-center clinical trial, we assessed the consistence and comparability of the quantitative parameters of the eight PET/CT units that will be used in this trial. PET/CT images were scanned using a PET NEMA image quality phantom (Biodex) on the eight units of Discovery PET/CT 690 from GE Healthcare. The scanning parameters were the same with the ones to be used in the planned trial.

Prognostic value of cancer antigen -125 for lung adenocarcinoma patients with brain metastasis: A random survival forest prognostic model.

Using random survival forest, this study was intended to evaluate the prognostic value of serum markers for lung adenocarcinoma patients with brain metastasis (BM), and tried to integrate them into a prognostic model. During 2010 to 2015, the patients were retrieved from two medical centers. Besides the Cox proportional hazards regression, the random survival forest (RSF) were also used to develop prognostic model from the group A (n = 142).

Therapeutic response and long-term outcome of differentiated thyroid cancer with pulmonary metastases treated by radioiodine therapy.

Objective: To explore the therapeutic response (TR) and long-term outcomes of iodine-131 (I-131) treatment for patients with differentiated thyroid cancer and pulmonary metastases (DTC+PM), as well as the association between the assessment of TR and long-term outcomes.

Methods: This retrospective study comprised 151 DTC+PM patients. TR was evaluated by changes in serum levels of thyroglobulin, anatomic imaging and iodine uptake in pulmonary nodules; logistic regression was applied to identify predictors.

Lean body mass is better than body surface area in correcting GFR.

Purpose: The Gates-based renography (gGFR) and plasma-based clearance rate (pGFR) are conventionally corrected with body surface area (BSA). Limited studies indicated that the lean body mass (LBM) might be better than BSA in correcting pGFR. Therefore, we suggest that LBM is also better in correcting gGFR and improve the correlation coefficient between gGFR and pGFR.

Correlation between an interleukin-6 -572C/G polymorphism and chronic periodontitis.

Genetic polymorphisms in the interleukin-6 (IL-6) gene are associated with bone homeostasis and diseases characterized by bone loss. The aim of this study was to investigate the correlation between the IL-6-572C/G polymorphism and the risk of chronic periodontitis in a Chinese Han population. The IL-6-572C/G polymorphism was genotyped in 93 patients suffering from chronic periodontitis and 96 control subjects by polymerase chain reaction-restriction fragment length polymorphism.

Status of nuclear medicine in Beijing: insights from the Beijing Quality Control Centre Survey 2005-2006.

Objective: To evaluate the status of nuclear medicine in Beijing during 2005.

Methods: For evaluating the status, a survey was performed in September 2006 by postal questionnaires. Forty-two nuclear medicine departments in Beijing were investigated regarding staff, equipment and clinical applications.

Nuclear medicine scans in Beijing: insights from the Beijing Quality Control Centre Survey 2005-2006.

Objective: To survey nuclear medicine scans carried out in Beijing during 2005.

Methods: Forty-two nuclear medicine departments were surveyed by using mailed questionnaires sent during September 2006.

Results: By the end of January 2007, 30 out of 42 hospitals had replied to our survey.

Measurement of standard uptake value in dual-head coincidence system.

Unlabelled: The standard uptake value (SUV) is an important semi-quantitative parameter in positron emission tomography (PET). But SUV is not available in dual-head coincidence imaging system (DHC) which is widely used in clinical practice. This study was designed to develop a method for measuring SUV in DHC system, and then compared SUV in DHC and SUV in PET.

Noise components on positron emission tomography images.

Noise components on PET images were studied. The results showed that the square of synthetic noise Delta(2) and the square of signal-to-noise ratio (N/Delta)(2) varied with the signal intensity N and the relationships were respectively expressed with: Delta(2)=0.0395N(2)+0.