A prognostic model for lung adenocarcinoma based on cuproptosis and disulfidptosis related genes revealing the key prognostic role of FURIN.

Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Despite advances in treatment, the prognosis remains poor due to late diagnosis. Cuproptosis (driven by copper ion accumulation) and disulfidptosis (driven by disulfide bond accumulation) are novel forms of programmed cell death, closely linked to tumor initiation, progression, and resistance.

Progress and prospects of Parkinson's disease with depression research: A global bibliometric analysis based on CiteSpace.

Background: Parkinson's disease (PD) is a common neurodegenerative disorder marked by motor impairments such as stiffness, involuntary shaking, and slowed movement. In addition, PD patients frequently experience nonmotor symptoms, especially depression. This study uses a mixed-methods scientometric analysis to review global research trends and advancements in PD and depression.