Publications by authors named "Jiangzham Li"
Article Synopsis
- Developed a microarray for diagnosing chromosomal disorders using large genomic DNA clones, targeting areas linked to over 40 human genomic disorders and subtelomeric regions.
- Conducted chromosome microarray analysis (CMA) on 25 patients previously assessed with traditional cytogenetics, showing high sensitivity (96.7%) and specificity (99.1%).
- CMA offers advantages like examining multiple genomic regions simultaneously and identifying duplications missed by conventional methods, but it doesn't replace standard karyotyping and has limitations in detecting balanced changes and low-level mosaicism.
