Publications by authors named "Jiangyou Shi"

Article Synopsis
  • * A total of 102 patients with lumbar spondylosis were divided into two groups: one receiving RhBMP-2 and the other receiving autologous bone for spinal fusion, with their recovery and outcomes measured over 12 months.
  • * Results showed that the RhBMP-2 group had significantly better scores for spinal function, a higher fusion rate (86.27% vs 54.90%), and lower cage displacement (5.88% vs 21.57%)
View Article and Find Full Text PDF

Background: To investigate the biochemical changes in lumbar facet joint (LFJ) and intervertebral disc (IVD) with different degenerative grade by T2* mapping.

Methods: Sixty-eight patients with low back pain (study group) and 20 volunteers (control group) underwent standard MRI protocols and axial T2* mapping. Morphological evaluation of LFJ and IVD were performed on T2-weighted imaging according to Weishaupt and Pfirrmann grading system, respectively.

View Article and Find Full Text PDF

Background: Stem cell-related studies have been increasingly conducted to facilitate the regeneration of degenerative discs. However, analyses of high-impact articles focused on this topic are rare. This study aimed to determine and summarize the most-cited studies examining stem cells in the context of intervertebral disc degeneration (IDD).

View Article and Find Full Text PDF

Objective: This study aimed to explore the specific function of M2 macrophages in intervertebral disc degeneration (IDD).

Methods: Intervertebral disc (IVD) samples from normal (n = 4) and IDD (n = 6) patients were collected, and the expression of M2-polarized macrophage marker, CD206, was investigated using immunohistochemical staining. Nucleus pulposus cells (NPCs) in a TNF-α environment were obtained, and a mouse caudal IVD puncture model was established.

View Article and Find Full Text PDF