Publications by authors named "Jiangyao Xu"

InP QDs have shown a great potential as cadmium-free QDs alternatives in biomedical applications. It is essential to understand the biological fate and toxicity of InP QDs. In this study, we investigated the in vivo renal toxicity of InP/ZnS QDs terminated with different functional groups-hydroxyl (hQDs), amino (aQDs) and carboxyl (cQDs).

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Article Synopsis
  • Cancer stem cells are critical in tumor development and are potential targets for cancer vaccines, but no immunizations exist for them currently.
  • Researchers used the OCT4 protein, which is involved in early tumorigenesis, and combined it with keyhole limpet hemocyanin (KLH) and a Toll-like receptor 9 agonist (TLR9) to create a vaccine.
  • The OCT4-3 + TLR9 combination showed the strongest immune response and significantly inhibited tumor growth in mice, enhancing cytotoxic T cell activity and various immune-promoting cytokines.
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Multiple sclerosis (MS) is an autoimmune disease characterized by T cell infiltration and demyelination of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a classical preclinical animal model of MS. In this study, we found that rotating magnetic field (RMF) treatment exerts potential preventive effects on the discovery of EAE, including reducing the severity of the disease and delaying the onset of the disease.

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The annual increase in the production and the use of engineering quantum dots (QDs) have led to concern about exposure and safety of QDs. To resolve the risk of Cd release from QDs, a series of Cd-free QDs, represented by CuInS/ZnS QDs, has been developed in recent years. However, the toxicological profile of CuInS/ZnS QDs has not been fully elucidated, especially, their immunotoxicity.

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The biological effects of magnetic fields are a research hotspot in the field of biomedical engineering. In this study, we further investigated the effects of a rotating magnetic field (RMF; 0.2 T, 4 Hz) on the growth of human umbilical vein endothelial cells (HUVECs) and .

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