Light-Powered Self-Translation of an Asymmetric Friction Slider Using a Liquid Crystal Elastomer String Oscillator.

In recent years, there have been many studies focused on improving the performance of active materials; however, applying these materials to active machines still presents significant challenges. In this study, we introduce a light-powered self-translation system for an asymmetric friction slider using a liquid crystal elastomer (LCE) string oscillator. The self-translation system was composed of a hollow slide, two LCE fibers, and a mass ball.

Determining the number of attributes in the GDINA model.

Exploratory cognitive diagnosis models have been widely used in psychology, education and other fields. This paper focuses on determining the number of attributes in a widely used cognitive diagnosis model, the GDINA model. Under some conditions of cognitive diagnosis models, we prove that there exists a special structure for the covariance matrix of observed data.

A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.

Tau pathogenesis is a hallmark of many neurodegenerative diseases, including Alzheimer's disease (AD). Although the events leading to initial tau misfolding and subsequent tau spreading in patient brains are largely unknown, traumatic brain injury (TBI) may be a risk factor for tau-mediated neurodegeneration. Using a repetitive TBI (rTBI) paradigm, we report that rTBI induced somatic accumulation of phosphorylated and misfolded tau, as well as neurodegeneration across multiple brain areas in 7-month-old tau transgenic PS19 mice but not wild-type (WT) mice.

[Effect of lentivirus-mediated silencing of P75 neurotrophin receptor gene on osteogenic differentiation of bone marrow mesenchymal stem cells in rats].

Objective: To investigate the effect of small interfering RNA (siRNA) lentivirus-mediated silencing of P75 neurotrophin receptor (P75NTR) gene on osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) in rats.

Methods: Three lentivirus-mediated P75NTR gene siRNA sequences (P75NTR-siRNA-1, 2, 3) and negative control (NC)-siRNA were designed and transfected into the 3rd generation Sprague Dawley (SD) rat BMSCs. The cells morphological changes were observed under an inverted microscope, and the expressions of P75NTR gene and protein in cells were detected by real-time fluorescence quantitative PCR and Western blot.