Comparative analysis of oral saliva microbiomes and metabolites in Han population at different altitudes.

Objective: This study investigated the differences in oral saliva microbiota composition and metabolic products among Han Chinese populations living at different altitudes, as well as their correlations.

Method: The analysis was conducted using the 16S rRNA gene sequencing method and untargeted metabolomics.

Results: 16S gene sequencing results showed significant differences in bacterial diversity and composition between HH (High altitude Han) group and LH (Low altitude Han) group.